7 files changed, 18 insertions, 18 deletions
diff --git a/metadata/md5-cache/sci-biology/Manifest.gz b/metadata/md5-cache/sci-biology/Manifest.gz
index 08d87ae7ad83..d7ebf8b6ea7f 100644
--- a/metadata/md5-cache/sci-biology/Manifest.gz
+++ b/metadata/md5-cache/sci-biology/Manifest.gz
diff --git a/metadata/md5-cache/sci-biology/biosql-1.0.1-r2 b/metadata/md5-cache/sci-biology/biosql-1.0.1-r2
index 54c0036aa974..2db325d864b6 100644
--- a/metadata/md5-cache/sci-biology/biosql-1.0.1-r2
+++ b/metadata/md5-cache/sci-biology/biosql-1.0.1-r2
@@ -2,11 +2,11 @@ DEFINED_PHASES=install postinst
 DEPEND=mysql? ( dev-perl/DBD-mysql ) postgres? ( dev-perl/DBD-Pg )
 DESCRIPTION=A generic bioinformatics relational database model
 EAPI=8
-HOMEPAGE=http://www.biosql.org/
+HOMEPAGE=https://biosql.org/
 IUSE=mysql postgres
 KEYWORDS=amd64 x86
 LICENSE=LGPL-3
 RDEPEND=mysql? ( dev-perl/DBD-mysql ) postgres? ( dev-perl/DBD-Pg ) dev-lang/perl
 SLOT=0
-SRC_URI=http://biosql.org/DIST/biosql-1.0.1.tar.bz2
-_md5_=6438fefd6b37886a8a237f7e9b0c1258
+SRC_URI=https://biosql.org/DIST/biosql-1.0.1.tar.bz2
+_md5_=17f139bd8463877fe11118d9b9cc16e2
diff --git a/metadata/md5-cache/sci-biology/exonerate-2.2.0-r3 b/metadata/md5-cache/sci-biology/exonerate-2.2.0-r3
index 3de153641c78..90c6b0ae6fc3 100644
--- a/metadata/md5-cache/sci-biology/exonerate-2.2.0-r3
+++ b/metadata/md5-cache/sci-biology/exonerate-2.2.0-r3
@@ -12,6 +12,6 @@ RDEPEND=dev-libs/glib:2
 REQUIRED_USE=test? ( utils )
 RESTRICT=!test? ( test )
 SLOT=0
-SRC_URI=http://ftp.ebi.ac.uk/pub/software/vertebrategenomics/exonerate/exonerate-2.2.0.tar.gz
+SRC_URI=https://ftp.ebi.ac.uk/pub/software/vertebrategenomics/exonerate/exonerate-2.2.0.tar.gz
 _eclasses_=autotools	9e6965bfaa00f52cc61e0d4bc44c87b3	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	5ca4e49abed8e3a2f7b56920eadee157	toolchain-funcs	1542e649be915f43f6908a9e93909961
-_md5_=1e7139985e79a73dd3eda616d23bafc0
+_md5_=4bd132dac9c502e76b3000e9c6d1e897
diff --git a/metadata/md5-cache/sci-biology/iedera-1.05-r2 b/metadata/md5-cache/sci-biology/iedera-1.05-r2
index b5a82162c772..cf1189d6b50b 100644
--- a/metadata/md5-cache/sci-biology/iedera-1.05-r2
+++ b/metadata/md5-cache/sci-biology/iedera-1.05-r2
@@ -1,12 +1,12 @@
 BDEPEND=sys-devel/gnuconfig >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.5:1.16 ) >=sys-devel/autoconf-2.71 >=sys-devel/libtool-2.4
 DEFINED_PHASES=prepare
-DESCRIPTION=A subset seed design tool for DNA sequence alignment
+DESCRIPTION=Subset seed design tool for DNA sequence alignment
 EAPI=8
-HOMEPAGE=http://bioinfo.lifl.fr/yass/iedera.php
+HOMEPAGE=https://bioinfo.lifl.fr/yass/iedera.php
 INHERIT=autotools
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 SLOT=0
-SRC_URI=http://bioinfo.lifl.fr/yass/files/iedera-1.05.tar.gz
+SRC_URI=https://bioinfo.lifl.fr/yass/files/iedera-1.05.tar.gz
 _eclasses_=autotools	9e6965bfaa00f52cc61e0d4bc44c87b3	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	5ca4e49abed8e3a2f7b56920eadee157	toolchain-funcs	1542e649be915f43f6908a9e93909961
-_md5_=a94a95bf7657c616d7b48d8bc45068c7
+_md5_=c1df71458cdeda01ad17b744ef31dc36
diff --git a/metadata/md5-cache/sci-biology/muscle-3.8.31 b/metadata/md5-cache/sci-biology/muscle-3.8.31
index 67f9f261defd..2724c1e3cc8e 100644
--- a/metadata/md5-cache/sci-biology/muscle-3.8.31
+++ b/metadata/md5-cache/sci-biology/muscle-3.8.31
@@ -1,12 +1,12 @@
 DEFINED_PHASES=configure install
 DESCRIPTION=Multiple sequence comparison by log-expectation
 EAPI=7
-HOMEPAGE=http://www.drive5.com/muscle/
+HOMEPAGE=https://www.drive5.com/muscle/
 INHERIT=toolchain-funcs
 KEYWORDS=amd64 ~ppc x86
 LICENSE=public-domain
 RDEPEND=!sci-libs/libmuscle
 SLOT=0
-SRC_URI=http://www.drive5.com/muscle/downloads3.8.31/muscle3.8.31_src.tar.gz
+SRC_URI=https://www.drive5.com/muscle/downloads3.8.31/muscle3.8.31_src.tar.gz
 _eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	toolchain-funcs	1542e649be915f43f6908a9e93909961
-_md5_=70730a85bf27816f07c7b7498e5adc91
+_md5_=373aea64d7c96030dbc1a9c4404f3985
diff --git a/metadata/md5-cache/sci-biology/pals-1.0-r2 b/metadata/md5-cache/sci-biology/pals-1.0-r2
index f25b22a41235..611ad72b2900 100644
--- a/metadata/md5-cache/sci-biology/pals-1.0-r2
+++ b/metadata/md5-cache/sci-biology/pals-1.0-r2
@@ -1,11 +1,11 @@
 DEFINED_PHASES=configure install
 DESCRIPTION=Pairwise Aligner for Long Sequences
 EAPI=8
-HOMEPAGE=http://www.drive5.com/pals/
+HOMEPAGE=https://www.drive5.com/pals/
 INHERIT=toolchain-funcs
 KEYWORDS=amd64 x86
 LICENSE=public-domain
 SLOT=0
-SRC_URI=http://www.drive5.com/pals/pals_source.tar.gz -> pals-1.0.tar.gz
+SRC_URI=https://www.drive5.com/pals/pals_source.tar.gz -> pals-1.0.tar.gz
 _eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	toolchain-funcs	1542e649be915f43f6908a9e93909961
-_md5_=0374a4cc1893f560fdb963ab9e27c56b
+_md5_=03270366228400ac56642b59fb067532
diff --git a/metadata/md5-cache/sci-biology/trf-4.04-r2 b/metadata/md5-cache/sci-biology/trf-4.04-r2
index 30e1962524fe..46eab303fe68 100644
--- a/metadata/md5-cache/sci-biology/trf-4.04-r2
+++ b/metadata/md5-cache/sci-biology/trf-4.04-r2
@@ -1,10 +1,10 @@
 DEFINED_PHASES=install unpack
 DESCRIPTION=Tandem Repeats Finder
 EAPI=8
-HOMEPAGE=http://tandem.bu.edu/trf/trf.html
+HOMEPAGE=https://tandem.bu.edu/trf/trf.html
 KEYWORDS=amd64 x86
 LICENSE=trf
 RESTRICT=mirror bindist
 SLOT=0
-SRC_URI=http://tandem.bu.edu/trf/downloads/trf404.linux
-_md5_=7a6d356b931b70a39c33d922bd23adb1
+SRC_URI=https://tandem.bu.edu/trf/downloads/trf404.linux
+_md5_=44fad2daec87377702c578544bf008e5