gentoo resync : 18.11.2019

32 files changed, 48 insertions, 50 deletions

diff --git a/metadata/md5-cache/sci-biology/HTSeq-0.9.1 b/metadata/md5-cache/sci-biology/HTSeq-0.9.1
index 0c3fe088d9cd..fe956bd77481 100644
--- a/metadata/md5-cache/sci-biology/HTSeq-0.9.1
+++ b/metadata/md5-cache/sci-biology/HTSeq-0.9.1
@@ -10,5 +10,5 @@ RDEPEND=dev-python/numpy[python_targets_python2_7(-)?,python_targets_python3_5(-
 REQUIRED_USE=|| ( python_targets_python2_7 python_targets_python3_5 python_targets_python3_6 )
 SLOT=0
 SRC_URI=mirror://pypi/H/HTSeq/HTSeq-0.9.1.tar.gz
-_eclasses_=distutils-r1	5ef20774410ba92b3fef636ca7945d52	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=distutils-r1	7d3cd47abcaee18ca62edf0d7bb60472	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=41aaefa741e4fde04bbda02ac66eba05
diff --git a/metadata/md5-cache/sci-biology/HTSeq-9999 b/metadata/md5-cache/sci-biology/HTSeq-9999
index 63132d858f67..aeb34165b840 100644
--- a/metadata/md5-cache/sci-biology/HTSeq-9999
+++ b/metadata/md5-cache/sci-biology/HTSeq-9999
@@ -9,5 +9,5 @@ PROPERTIES=live
 RDEPEND=dev-python/numpy[python_targets_python2_7(-)?,python_targets_python3_5(-)?,python_targets_python3_6(-)?,-python_single_target_python2_7(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-)] dev-python/matplotlib[python_targets_python2_7(-)?,python_targets_python3_5(-)?,python_targets_python3_6(-)?,-python_single_target_python2_7(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-)] sci-biology/pysam[python_targets_python2_7(-)?,python_targets_python3_5(-)?,python_targets_python3_6(-)?,-python_single_target_python2_7(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-)] python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) python_targets_python3_5? ( dev-lang/python:3.5 ) python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,python_targets_python3_5(-)?,python_targets_python3_6(-)?,-python_single_target_python2_7(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 python_targets_python3_5 python_targets_python3_6 )
 SLOT=0
-_eclasses_=distutils-r1	5ef20774410ba92b3fef636ca7945d52	git-r3	562b380fc59ae6a8622171d0acb777d1	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=distutils-r1	7d3cd47abcaee18ca62edf0d7bb60472	git-r3	562b380fc59ae6a8622171d0acb777d1	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=41aaefa741e4fde04bbda02ac66eba05
diff --git a/metadata/md5-cache/sci-biology/Manifest.gz b/metadata/md5-cache/sci-biology/Manifest.gz
index 20f1608ba642..2749f8aea753 100644
--- a/metadata/md5-cache/sci-biology/Manifest.gz
+++ b/metadata/md5-cache/sci-biology/Manifest.gz
diff --git a/metadata/md5-cache/sci-biology/amos-3.1.0-r4 b/metadata/md5-cache/sci-biology/amos-3.1.0-r4
index 104e175098df..3403dedb9d0b 100644
--- a/metadata/md5-cache/sci-biology/amos-3.1.0-r4
+++ b/metadata/md5-cache/sci-biology/amos-3.1.0-r4
@@ -6,9 +6,9 @@ HOMEPAGE=http://amos.sourceforge.net/
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=Artistic
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] dev-perl/DBI dev-perl/Statistics-Descriptive sci-biology/mummer
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] dev-perl/DBI dev-perl/Statistics-Descriptive sci-biology/mummer
 REQUIRED_USE=python_targets_python2_7
 SLOT=0
 SRC_URI=mirror://sourceforge/amos/amos-3.1.0.tar.gz https://dev.gentoo.org/~soap/distfiles/amos-3.1.0-fix-c++14.patch.bz2
-_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=aec6d1c76d5ea621c66e803800e2b3c4
diff --git a/metadata/md5-cache/sci-biology/bamtools-2.5.1 b/metadata/md5-cache/sci-biology/bamtools-2.5.1
index ab5514f91cfc..fd0b353476b6 100644
--- a/metadata/md5-cache/sci-biology/bamtools-2.5.1
+++ b/metadata/md5-cache/sci-biology/bamtools-2.5.1
@@ -1,14 +1,13 @@
 BDEPEND=virtual/pkgconfig dev-util/ninja >=dev-util/cmake-3.9.6
-DEFINED_PHASES=compile configure install prepare setup test
+DEFINED_PHASES=compile configure install prepare test
 DEPEND=>=dev-libs/jsoncpp-1.8.0:= sys-libs/zlib:=
 DESCRIPTION=A programmer's API and an end-user's toolkit for handling BAM files
 EAPI=7
 HOMEPAGE=https://github.com/pezmaster31/bamtools
-IUSE=static-libs
 KEYWORDS=~amd64 ~x86
 LICENSE=MIT
 RDEPEND=>=dev-libs/jsoncpp-1.8.0:= sys-libs/zlib:=
 SLOT=0/2.5.1
 SRC_URI=https://github.com/pezmaster31/bamtools/archive/v2.5.1.tar.gz -> bamtools-2.5.1.tar.gz
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
-_md5_=bddaa64daf006313f77c6152fbc41a8b
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_md5_=1243ce3dd09eed43ed1efea1c14e88e2
diff --git a/metadata/md5-cache/sci-biology/bamtools-9999 b/metadata/md5-cache/sci-biology/bamtools-9999
index 299ab216ffc3..0fd84d06e15f 100644
--- a/metadata/md5-cache/sci-biology/bamtools-9999
+++ b/metadata/md5-cache/sci-biology/bamtools-9999
@@ -1,13 +1,12 @@
 BDEPEND=virtual/pkgconfig dev-util/ninja >=dev-util/cmake-3.9.6 >=dev-vcs/git-1.8.2.1[curl]
-DEFINED_PHASES=compile configure install prepare setup test unpack
+DEFINED_PHASES=compile configure install prepare test unpack
 DEPEND=>=dev-libs/jsoncpp-1.8.0:= sys-libs/zlib:=
 DESCRIPTION=A programmer's API and an end-user's toolkit for handling BAM files
 EAPI=7
 HOMEPAGE=https://github.com/pezmaster31/bamtools
-IUSE=static-libs
 LICENSE=MIT
 PROPERTIES=live
 RDEPEND=>=dev-libs/jsoncpp-1.8.0:= sys-libs/zlib:=
 SLOT=0/9999
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	git-r3	562b380fc59ae6a8622171d0acb777d1	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
-_md5_=bddaa64daf006313f77c6152fbc41a8b
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	git-r3	562b380fc59ae6a8622171d0acb777d1	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_md5_=1243ce3dd09eed43ed1efea1c14e88e2
diff --git a/metadata/md5-cache/sci-biology/bcftools-1.5 b/metadata/md5-cache/sci-biology/bcftools-1.5
index 7bccc2b979bb..154e803c344d 100644
--- a/metadata/md5-cache/sci-biology/bcftools-1.5
+++ b/metadata/md5-cache/sci-biology/bcftools-1.5
@@ -10,5 +10,5 @@ RDEPEND=dev-lang/perl =sci-libs/htslib-1.5*:= sys-libs/zlib python_targets_pytho
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=https://github.com/samtools/bcftools/releases/download/1.5/bcftools-1.5.tar.bz2
-_eclasses_=multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=e289371e3fec376baf8fe36c652ca521
diff --git a/metadata/md5-cache/sci-biology/bcftools-1.9 b/metadata/md5-cache/sci-biology/bcftools-1.9
index 07998223d8a1..c9155eb6ceae 100644
--- a/metadata/md5-cache/sci-biology/bcftools-1.9
+++ b/metadata/md5-cache/sci-biology/bcftools-1.9
@@ -1,14 +1,14 @@
 DEFINED_PHASES=configure prepare setup
-DEPEND=dev-lang/perl =sci-libs/htslib-1.9*:= sys-libs/zlib:= python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)]
+DEPEND=dev-lang/perl =sci-libs/htslib-1.9*:= sys-libs/zlib:= python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)]
 DESCRIPTION=Utilities for variant calling and manipulating VCF and BCF files
 EAPI=7
 HOMEPAGE=http://www.htslib.org
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=MIT
-RDEPEND=dev-lang/perl =sci-libs/htslib-1.9*:= sys-libs/zlib:= python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)]
+RDEPEND=dev-lang/perl =sci-libs/htslib-1.9*:= sys-libs/zlib:= python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)]
 REQUIRED_USE=python_targets_python2_7
 SLOT=0
 SRC_URI=https://github.com/samtools/bcftools/releases/download/1.9/bcftools-1.9.tar.bz2
-_eclasses_=multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=67c63191569c3370d6eca3ec783afbea
diff --git a/metadata/md5-cache/sci-biology/bedtools-2.26.0 b/metadata/md5-cache/sci-biology/bedtools-2.26.0
index 6ddba08336e8..f8380911b5cc 100644
--- a/metadata/md5-cache/sci-biology/bedtools-2.26.0
+++ b/metadata/md5-cache/sci-biology/bedtools-2.26.0
@@ -9,5 +9,5 @@ LICENSE=GPL-2
 RDEPEND=sys-libs/zlib
 SLOT=0
 SRC_URI=https://github.com/arq5x/bedtools2/releases/download/v2.26.0/bedtools-2.26.0.tar.gz https://dev.gentoo.org/~mgorny/dist/bedtools-2.26.0-fix-buildsystem.patch.bz2
-_eclasses_=desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=93c7c9cb11de4ad32cab7183dc2e6512
diff --git a/metadata/md5-cache/sci-biology/biopandas-0.2.1 b/metadata/md5-cache/sci-biology/biopandas-0.2.1
index 89c00fdaa6e0..59728036e472 100644
--- a/metadata/md5-cache/sci-biology/biopandas-0.2.1
+++ b/metadata/md5-cache/sci-biology/biopandas-0.2.1
@@ -10,5 +10,5 @@ RDEPEND=dev-python/numpy[python_targets_python2_7(-)?,python_targets_python3_5(-
 REQUIRED_USE=|| ( python_targets_python2_7 python_targets_python3_5 python_targets_python3_6 )
 SLOT=0
 SRC_URI=mirror://pypi/B/BioPandas/biopandas-0.2.1.tar.gz
-_eclasses_=distutils-r1	5ef20774410ba92b3fef636ca7945d52	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=distutils-r1	7d3cd47abcaee18ca62edf0d7bb60472	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=5a0449fad95f6d2e6b0930487808e8ef
diff --git a/metadata/md5-cache/sci-biology/biopython-1.68 b/metadata/md5-cache/sci-biology/biopython-1.68
index f14e3b40aff1..769c92afe28d 100644
--- a/metadata/md5-cache/sci-biology/biopython-1.68
+++ b/metadata/md5-cache/sci-biology/biopython-1.68
@@ -10,5 +10,5 @@ RDEPEND=dev-python/matplotlib[python_targets_python2_7(-)?,-python_single_target
 REQUIRED_USE=|| ( python_targets_pypy python_targets_python2_7 python_targets_python3_5 )
 SLOT=0
 SRC_URI=http://www.biopython.org/DIST/biopython-1.68.tar.gz
-_eclasses_=desktop	b1d22ac8bdd4679ab79c71aca235009d	distutils-r1	5ef20774410ba92b3fef636ca7945d52	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	b1d22ac8bdd4679ab79c71aca235009d	distutils-r1	7d3cd47abcaee18ca62edf0d7bb60472	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=09edbf25123b14fe83187c2577a871a0
diff --git a/metadata/md5-cache/sci-biology/biopython-1.71 b/metadata/md5-cache/sci-biology/biopython-1.71
index 0f557175ef9d..5180ceb20c43 100644
--- a/metadata/md5-cache/sci-biology/biopython-1.71
+++ b/metadata/md5-cache/sci-biology/biopython-1.71
@@ -11,5 +11,5 @@ RDEPEND=dev-python/matplotlib[python_targets_python2_7(-)?,python_targets_python
 REQUIRED_USE=|| ( python_targets_python2_7 python_targets_python3_5 python_targets_python3_6 )
 SLOT=0
 SRC_URI=mirror://pypi/b/biopython/biopython-1.71.tar.gz
-_eclasses_=distutils-r1	5ef20774410ba92b3fef636ca7945d52	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=distutils-r1	7d3cd47abcaee18ca62edf0d7bb60472	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=c8c05d4c9d3dc460d2dbb68c556d1984
diff --git a/metadata/md5-cache/sci-biology/biopython-1.73 b/metadata/md5-cache/sci-biology/biopython-1.73
index 31aedf67f052..21d285c23369 100644
--- a/metadata/md5-cache/sci-biology/biopython-1.73
+++ b/metadata/md5-cache/sci-biology/biopython-1.73
@@ -11,5 +11,5 @@ RDEPEND=dev-python/matplotlib[python_targets_python2_7(-)?,python_targets_python
 REQUIRED_USE=|| ( python_targets_python2_7 python_targets_python3_5 python_targets_python3_6 python_targets_python3_7 )
 SLOT=0
 SRC_URI=mirror://pypi/b/biopython/biopython-1.73.tar.gz
-_eclasses_=distutils-r1	5ef20774410ba92b3fef636ca7945d52	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=distutils-r1	7d3cd47abcaee18ca62edf0d7bb60472	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=c467f0810536bbd7ae60a0ba82fbd422
diff --git a/metadata/md5-cache/sci-biology/express-1.5.1 b/metadata/md5-cache/sci-biology/express-1.5.1
index a934c3c2c870..dd9e41ee18e0 100644
--- a/metadata/md5-cache/sci-biology/express-1.5.1
+++ b/metadata/md5-cache/sci-biology/express-1.5.1
@@ -8,5 +8,5 @@ LICENSE=Artistic
 RDEPEND=>=dev-libs/boost-1.52.0:= dev-libs/protobuf dev-util/google-perftools sci-biology/bamtools sys-libs/zlib
 SLOT=0
 SRC_URI=http://bio.math.berkeley.edu/eXpress/downloads/express-1.5.1/express-1.5.1-src.tgz
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=10c478f1e1a9a533322963cf4c2e92f8
diff --git a/metadata/md5-cache/sci-biology/fasttree-2.1.8 b/metadata/md5-cache/sci-biology/fasttree-2.1.8
index 9cecb46a3073..78c3a726b922 100644
--- a/metadata/md5-cache/sci-biology/fasttree-2.1.8
+++ b/metadata/md5-cache/sci-biology/fasttree-2.1.8
@@ -9,5 +9,5 @@ LICENSE=GPL-2
 REQUIRED_USE=?? ( double-precision cpu_flags_x86_sse3 )
 SLOT=0
 SRC_URI=http://www.microbesonline.org/fasttree/FastTree-2.1.8.c http://www.microbesonline.org/fasttree/FastTreeUPGMA.c -> FastTreeUPGMA-2.1.8.c http://www.microbesonline.org/fasttree/MOTreeComparison.tar.gz -> MOTreeComparison-2.1.8.tar.gz
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=5a3e768febbbadcd5c8a4141dd49e11c
diff --git a/metadata/md5-cache/sci-biology/kallisto-0.43.1 b/metadata/md5-cache/sci-biology/kallisto-0.43.1
index 89735eeb2e78..ab02546790cd 100644
--- a/metadata/md5-cache/sci-biology/kallisto-0.43.1
+++ b/metadata/md5-cache/sci-biology/kallisto-0.43.1
@@ -8,5 +8,5 @@ LICENSE=BSD
 RDEPEND=sci-libs/hdf5:= sys-libs/zlib:=
 SLOT=0
 SRC_URI=https://github.com/pachterlab/kallisto/archive/v0.43.1.tar.gz -> kallisto-0.43.1.tar.gz
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=b5fc562bf49e70db44b86bc5702ae9f2
diff --git a/metadata/md5-cache/sci-biology/kallisto-9999 b/metadata/md5-cache/sci-biology/kallisto-9999
index ddb046721e1f..89eacd71a433 100644
--- a/metadata/md5-cache/sci-biology/kallisto-9999
+++ b/metadata/md5-cache/sci-biology/kallisto-9999
@@ -7,5 +7,5 @@ LICENSE=BSD
 PROPERTIES=live
 RDEPEND=sci-libs/hdf5:= sys-libs/zlib:=
 SLOT=0
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	git-r3	562b380fc59ae6a8622171d0acb777d1	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	git-r3	562b380fc59ae6a8622171d0acb777d1	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=b5fc562bf49e70db44b86bc5702ae9f2
diff --git a/metadata/md5-cache/sci-biology/last-299-r1 b/metadata/md5-cache/sci-biology/last-299-r1
index 6e0fdd404b45..3b46dcf698a1 100644
--- a/metadata/md5-cache/sci-biology/last-299-r1
+++ b/metadata/md5-cache/sci-biology/last-299-r1
@@ -6,9 +6,9 @@ HOMEPAGE=http://last.cbrc.jp/
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-3
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)]
 REQUIRED_USE=python_targets_python2_7
 SLOT=0
 SRC_URI=http://last.cbrc.jp/last-299.zip
-_eclasses_=multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=ec5206661373a6ef6ad77450dfbdb915
diff --git a/metadata/md5-cache/sci-biology/meme-4.11.2_p2 b/metadata/md5-cache/sci-biology/meme-4.11.2_p2
index e99ab1170364..e36a50305d57 100644
--- a/metadata/md5-cache/sci-biology/meme-4.11.2_p2
+++ b/metadata/md5-cache/sci-biology/meme-4.11.2_p2
@@ -1,14 +1,14 @@
 DEFINED_PHASES=configure install prepare setup test
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] app-shells/tcsh dev-libs/libxml2:2 dev-libs/libxslt sys-libs/zlib app-text/ghostscript-gpl media-gfx/imagemagick dev-lang/perl:= dev-perl/HTML-Parser dev-perl/HTML-Template dev-perl/Log-Log4perl dev-perl/Math-CDF dev-perl/XML-Compile-SOAP dev-perl/XML-Compile-WSDL11 dev-perl/XML-Parser dev-perl/XML-Simple virtual/perl-Data-Dumper virtual/perl-Exporter virtual/perl-File-Path virtual/perl-File-Spec virtual/perl-File-Temp virtual/perl-Getopt-Long virtual/perl-Scalar-List-Utils virtual/perl-Time-HiRes mpi? ( virtual/mpi ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] app-shells/tcsh dev-libs/libxml2:2 dev-libs/libxslt sys-libs/zlib app-text/ghostscript-gpl media-gfx/imagemagick dev-lang/perl:= dev-perl/HTML-Parser dev-perl/HTML-Template dev-perl/Log-Log4perl dev-perl/Math-CDF dev-perl/XML-Compile-SOAP dev-perl/XML-Compile-WSDL11 dev-perl/XML-Parser dev-perl/XML-Simple virtual/perl-Data-Dumper virtual/perl-Exporter virtual/perl-File-Path virtual/perl-File-Spec virtual/perl-File-Temp virtual/perl-Getopt-Long virtual/perl-Scalar-List-Utils virtual/perl-Time-HiRes mpi? ( virtual/mpi ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
 DESCRIPTION=The MEME/MAST system - Motif discovery and search
 EAPI=6
 HOMEPAGE=http://meme-suite.org/tools/meme
 IUSE=debug doc examples mpi python_targets_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=meme
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] app-shells/tcsh dev-libs/libxml2:2 dev-libs/libxslt sys-libs/zlib app-text/ghostscript-gpl media-gfx/imagemagick dev-lang/perl:= dev-perl/HTML-Parser dev-perl/HTML-Template dev-perl/Log-Log4perl dev-perl/Math-CDF dev-perl/XML-Compile-SOAP dev-perl/XML-Compile-WSDL11 dev-perl/XML-Parser dev-perl/XML-Simple virtual/perl-Data-Dumper virtual/perl-Exporter virtual/perl-File-Path virtual/perl-File-Spec virtual/perl-File-Temp virtual/perl-Getopt-Long virtual/perl-Scalar-List-Utils virtual/perl-Time-HiRes mpi? ( virtual/mpi )
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] app-shells/tcsh dev-libs/libxml2:2 dev-libs/libxslt sys-libs/zlib app-text/ghostscript-gpl media-gfx/imagemagick dev-lang/perl:= dev-perl/HTML-Parser dev-perl/HTML-Template dev-perl/Log-Log4perl dev-perl/Math-CDF dev-perl/XML-Compile-SOAP dev-perl/XML-Compile-WSDL11 dev-perl/XML-Parser dev-perl/XML-Simple virtual/perl-Data-Dumper virtual/perl-Exporter virtual/perl-File-Path virtual/perl-File-Spec virtual/perl-File-Temp virtual/perl-Getopt-Long virtual/perl-Scalar-List-Utils virtual/perl-Time-HiRes mpi? ( virtual/mpi )
 REQUIRED_USE=python_targets_python2_7
 SLOT=0
 SRC_URI=http://meme-suite.org/meme-software/4.11.2/meme_4.11.2.tar.gz
-_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	estack	43ddf5aaffa7a8d0482df54d25a66a1f	libtool	f143db5a74ccd9ca28c1234deffede96	multilib	1d91b03d42ab6308b5f4f6b598ed110e	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	versionator	2352c3fc97241f6a02042773c8287748
+_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	estack	43ddf5aaffa7a8d0482df54d25a66a1f	libtool	f143db5a74ccd9ca28c1234deffede96	multilib	1d91b03d42ab6308b5f4f6b598ed110e	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	versionator	2352c3fc97241f6a02042773c8287748
 _md5_=a4080439675628436c06de8db9f59c6e
diff --git a/metadata/md5-cache/sci-biology/pysam-0.12.0.1 b/metadata/md5-cache/sci-biology/pysam-0.12.0.1
index 4bd8113eeade..7ec43c69c6e0 100644
--- a/metadata/md5-cache/sci-biology/pysam-0.12.0.1
+++ b/metadata/md5-cache/sci-biology/pysam-0.12.0.1
@@ -10,5 +10,5 @@ RDEPEND==sci-libs/htslib-1.5*:= python_targets_python2_7? ( >=dev-lang/python-2.
 REQUIRED_USE=|| ( python_targets_python2_7 python_targets_python3_5 python_targets_python3_6 )
 SLOT=0
 SRC_URI=mirror://pypi/p/pysam/pysam-0.12.0.1.tar.gz
-_eclasses_=distutils-r1	5ef20774410ba92b3fef636ca7945d52	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=distutils-r1	7d3cd47abcaee18ca62edf0d7bb60472	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=9b1bc42dd99cc41b191559fb7a9fa4c6
diff --git a/metadata/md5-cache/sci-biology/samtools-0.1.20-r3 b/metadata/md5-cache/sci-biology/samtools-0.1.20-r3
index 4fd8371698ae..f060eac1c582 100644
--- a/metadata/md5-cache/sci-biology/samtools-0.1.20-r3
+++ b/metadata/md5-cache/sci-biology/samtools-0.1.20-r3
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile install postinst prepare setup
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] sys-libs/ncurses:0= dev-lang/perl virtual/pkgconfig
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] sys-libs/ncurses:0= dev-lang/perl virtual/pkgconfig
 DESCRIPTION=Utilities for analysing and manipulating the SAM/BAM alignment formats
 EAPI=6
 HOMEPAGE=http://samtools.sourceforge.net/
 IUSE=examples python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=MIT
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] sys-libs/ncurses:0= dev-lang/perl
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] sys-libs/ncurses:0= dev-lang/perl
 REQUIRED_USE=python_targets_python2_7
 SLOT=0.1-legacy
 SRC_URI=https://github.com/samtools/samtools/archive/0.1.20.tar.gz -> samtools-0.1.20.tar.gz
-_eclasses_=multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=fa48f0b2be780a9264eb9d727ec53335
diff --git a/metadata/md5-cache/sci-biology/samtools-1.5 b/metadata/md5-cache/sci-biology/samtools-1.5
index 401a3779907e..6f744a18e666 100644
--- a/metadata/md5-cache/sci-biology/samtools-1.5
+++ b/metadata/md5-cache/sci-biology/samtools-1.5
@@ -10,5 +10,5 @@ RDEPEND=dev-lang/perl =sci-libs/htslib-1.5* sys-libs/ncurses:0= sys-libs/zlib py
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=mirror://sourceforge/samtools/samtools-1.5.tar.bz2
-_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	libtool	f143db5a74ccd9ca28c1234deffede96	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	libtool	f143db5a74ccd9ca28c1234deffede96	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-r1	ce1cd23cfdc1848e8e32743efe34f299	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=8d92b4a814f62eab87bac2be22c2470c
diff --git a/metadata/md5-cache/sci-biology/samtools-1.9 b/metadata/md5-cache/sci-biology/samtools-1.9
index a828dac01c97..5712d1ee23f0 100644
--- a/metadata/md5-cache/sci-biology/samtools-1.9
+++ b/metadata/md5-cache/sci-biology/samtools-1.9
@@ -1,15 +1,15 @@
 BDEPEND=>=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
 DEFINED_PHASES=install prepare setup test
-DEPEND=dev-lang/perl =sci-libs/htslib-1.9* sys-libs/ncurses:0= sys-libs/zlib:= python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] virtual/pkgconfig
+DEPEND=dev-lang/perl =sci-libs/htslib-1.9* sys-libs/ncurses:0= sys-libs/zlib:= python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] virtual/pkgconfig
 DESCRIPTION=Utilities for analysing and manipulating the SAM/BAM alignment formats
 EAPI=7
 HOMEPAGE=http://www.htslib.org/
 IUSE=examples python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=MIT
-RDEPEND=dev-lang/perl =sci-libs/htslib-1.9* sys-libs/ncurses:0= sys-libs/zlib:= python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)]
+RDEPEND=dev-lang/perl =sci-libs/htslib-1.9* sys-libs/ncurses:0= sys-libs/zlib:= python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)]
 REQUIRED_USE=python_targets_python2_7
 SLOT=0
 SRC_URI=mirror://sourceforge/samtools/samtools-1.9.tar.bz2
-_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	libtool	f143db5a74ccd9ca28c1234deffede96	multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	libtool	f143db5a74ccd9ca28c1234deffede96	multilib	1d91b03d42ab6308b5f4f6b598ed110e	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=7e8913a97cbbcf5ee0158a89a42fa92c
diff --git a/metadata/md5-cache/sci-biology/seqan-1.4.2-r1 b/metadata/md5-cache/sci-biology/seqan-1.4.2-r1
index df28f84cf6bb..91196112bd75 100644
--- a/metadata/md5-cache/sci-biology/seqan-1.4.2-r1
+++ b/metadata/md5-cache/sci-biology/seqan-1.4.2-r1
@@ -10,5 +10,5 @@ RDEPEND=app-arch/bzip2 sys-libs/zlib
 REQUIRED_USE=cpu_flags_x86_sse4_1
 SLOT=1.4
 SRC_URI=http://packages.seqan.de/seqan-src/seqan-src-1.4.2.tar.gz
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=1b7be060ecec73f1e66596a71b90a92a
diff --git a/metadata/md5-cache/sci-biology/seqan-2.2.0-r1 b/metadata/md5-cache/sci-biology/seqan-2.2.0-r1
index d3b44ed33f95..fe1f3df84e95 100644
--- a/metadata/md5-cache/sci-biology/seqan-2.2.0-r1
+++ b/metadata/md5-cache/sci-biology/seqan-2.2.0-r1
@@ -10,5 +10,5 @@ RDEPEND=app-arch/bzip2 sys-libs/zlib !!sci-biology/seqan:2.0 !!sci-biology/seqan
 REQUIRED_USE=cpu_flags_x86_sse4_1
 SLOT=0
 SRC_URI=http://packages.seqan.de/seqan-src/seqan-src-2.2.0.tar.gz
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=aaf78a04252c5e6c2b92b04c7211b73c
diff --git a/metadata/md5-cache/sci-biology/seqan-2.4.0 b/metadata/md5-cache/sci-biology/seqan-2.4.0
index 0fa48696dd01..36af479f0660 100644
--- a/metadata/md5-cache/sci-biology/seqan-2.4.0
+++ b/metadata/md5-cache/sci-biology/seqan-2.4.0
@@ -10,5 +10,5 @@ RDEPEND=app-arch/bzip2:= sys-libs/zlib:= !!sci-biology/seqan:2.0 !!sci-biology/s
 REQUIRED_USE=cpu_flags_x86_sse4_1
 SLOT=0
 SRC_URI=https://github.com/seqan/seqan/archive/seqan-v2.4.0.tar.gz
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=ca34cde2b2fc2f8692469a016bc077f6
diff --git a/metadata/md5-cache/sci-biology/seqan-9999 b/metadata/md5-cache/sci-biology/seqan-9999
index 407314d77cef..80cf6c4fd380 100644
--- a/metadata/md5-cache/sci-biology/seqan-9999
+++ b/metadata/md5-cache/sci-biology/seqan-9999
@@ -9,5 +9,5 @@ PROPERTIES=live
 RDEPEND=app-arch/bzip2:= sys-libs/zlib:= !!sci-biology/seqan:2.0 !!sci-biology/seqan:2.1 !!sci-biology/seqan:2.2
 REQUIRED_USE=cpu_flags_x86_sse4_1
 SLOT=0
-_eclasses_=cmake-utils	91d6ef31dc426240577497cacbf2508c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	git-r3	562b380fc59ae6a8622171d0acb777d1	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	a5d9146ee60641275d46a91aab93d02f	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	git-r3	562b380fc59ae6a8622171d0acb777d1	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	b5f01473006ccc2cd78bc3dab20fced4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=954c2a9b05e60f6a61eb27c1cc720117
diff --git a/metadata/md5-cache/sci-biology/shrimp-2.2.3 b/metadata/md5-cache/sci-biology/shrimp-2.2.3
index 7120626f9ac5..f3c70f1f9de8 100644
--- a/metadata/md5-cache/sci-biology/shrimp-2.2.3
+++ b/metadata/md5-cache/sci-biology/shrimp-2.2.3
@@ -6,9 +6,9 @@ HOMEPAGE=http://compbio.cs.toronto.edu/shrimp/
 IUSE=custom-cflags +cpu_flags_x86_sse2 python_targets_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=shrimp
-RDEPEND=!sci-mathematics/cado-nfs python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)]
+RDEPEND=!sci-mathematics/cado-nfs python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)]
 REQUIRED_USE=python_targets_python2_7
 SLOT=0
 SRC_URI=http://compbio.cs.toronto.edu/shrimp/releases/SHRiMP_2_2_3.src.tar.gz
-_eclasses_=desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=98a7a2b9765ad5e245b1b7b9be67060b
diff --git a/metadata/md5-cache/sci-biology/tophat-2.1.1-r4 b/metadata/md5-cache/sci-biology/tophat-2.1.1-r4
index 5bf9e3e7f8c0..ab11763d27c7 100644
--- a/metadata/md5-cache/sci-biology/tophat-2.1.1-r4
+++ b/metadata/md5-cache/sci-biology/tophat-2.1.1-r4
@@ -1,14 +1,14 @@
 DEFINED_PHASES=configure install postinst prepare setup
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] dev-libs/boost:=[threads] dev-python/intervaltree[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] dev-python/sortedcontainers[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] sci-biology/samtools:0.1-legacy sci-biology/bowtie:2 virtual/pkgconfig sci-biology/seqan:1.4 >=sys-devel/autoconf-archive-2016.09.16 >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] dev-libs/boost:=[threads] dev-python/intervaltree[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] dev-python/sortedcontainers[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] sci-biology/samtools:0.1-legacy sci-biology/bowtie:2 virtual/pkgconfig sci-biology/seqan:1.4 >=sys-devel/autoconf-archive-2016.09.16 >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
 DESCRIPTION=Python-based splice junction mapper for RNA-Seq reads using bowtie2
 EAPI=6
 HOMEPAGE=https://ccb.jhu.edu/software/tophat/
 IUSE=debug python_targets_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=Artistic
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] dev-libs/boost:=[threads] dev-python/intervaltree[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] dev-python/sortedcontainers[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),python_single_target_python2_7(+)] sci-biology/samtools:0.1-legacy sci-biology/bowtie:2
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] dev-libs/boost:=[threads] dev-python/intervaltree[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] dev-python/sortedcontainers[python_targets_python2_7(-)?,-python_single_target_jython2_7(-),-python_single_target_pypy(-),-python_single_target_pypy3(-),-python_single_target_python3_5(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),python_single_target_python2_7(+)] sci-biology/samtools:0.1-legacy sci-biology/bowtie:2
 REQUIRED_USE=python_targets_python2_7
 SLOT=0
 SRC_URI=https://ccb.jhu.edu/software/tophat/downloads/tophat-2.1.1.tar.gz
-_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	25291c381052933ddf86bcffbfaff2ed	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=autotools	ea7865c8fba1ea8d3639f355fffe1a3c	desktop	b1d22ac8bdd4679ab79c71aca235009d	epatch	a1bf4756dba418a7238f3be0cb010c54	estack	43ddf5aaffa7a8d0482df54d25a66a1f	eutils	6e6c2737b59a4b982de6fb3ecefd87f8	flag-o-matic	8a43b9830f1e64a7a5fc0a276afa0275	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	3a0fc81f484bfdbd9c2b7448015a36e4	python-utils-r1	93ff6f0f8518926f2951ca70ce36e887	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=efee8069c83c578acac8e57b429ad985
diff --git a/metadata/md5-cache/sci-biology/uchime-4.2.40 b/metadata/md5-cache/sci-biology/uchime-4.2.40
index 8b9124878505..06978b8c2b54 100644
--- a/metadata/md5-cache/sci-biology/uchime-4.2.40
+++ b/metadata/md5-cache/sci-biology/uchime-4.2.40
@@ -8,5 +8,5 @@ KEYWORDS=amd64 x86 ~amd64-linux ~x86-linux
 LICENSE=public-domain
 SLOT=0
 SRC_URI=http://drive5.com/uchime/uchime4.2.40_src.tar.gz
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diff --git a/metadata/md5-cache/sci-biology/vienna-rna-2.1.1 b/metadata/md5-cache/sci-biology/vienna-rna-2.1.1
index 994e48759ab5..9731dc7ecab1 100644
--- a/metadata/md5-cache/sci-biology/vienna-rna-2.1.1
+++ b/metadata/md5-cache/sci-biology/vienna-rna-2.1.1
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 REQUIRED_USE=python? ( || ( python_targets_python2_7 ) )
 SLOT=0
 SRC_URI=http://www.tbi.univie.ac.at/~ronny/RNA/ViennaRNA-2.1.1.tar.gz
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diff --git a/metadata/md5-cache/sci-biology/vienna-rna-2.1.8 b/metadata/md5-cache/sci-biology/vienna-rna-2.1.8
index e4cb9abc7f85..bc7b0a022990 100644
--- a/metadata/md5-cache/sci-biology/vienna-rna-2.1.8
+++ b/metadata/md5-cache/sci-biology/vienna-rna-2.1.8
@@ -10,5 +10,5 @@ RDEPEND=dev-lang/perl media-libs/gd doc? ( dev-texlive/texlive-latex ) python? (
 REQUIRED_USE=python? ( || ( python_targets_python2_7 ) )
 SLOT=0
 SRC_URI=http://www.tbi.univie.ac.at/RNA/packages/source/ViennaRNA-2.1.8.tar.gz
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