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diff --git a/profiles/use.local.desc b/profiles/use.local.desc
index 911ed50c7966..ee8c7b53b213 100644
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+++ b/profiles/use.local.desc
@@ -7398,8 +7398,6 @@ sci-libs/libccd:double-precision - More precise calculations at the expense of s
sci-libs/libgeodecomp:hpx - Enables HPX backend
sci-libs/libgeodecomp:opencv - Enables OpenCV related code
sci-libs/libgeodecomp:silo - Enables SILO related code
-sci-libs/libghemical:mopac7 - Use sci-chemistry/mopac7 for semi-empirical calculations
-sci-libs/libghemical:mpqc - Use sci-chemistry/mpqc for quantum-mechanical calculations
sci-libs/liborigin:tools - Install opj2dat command line util
sci-libs/libqalculate:hardened - Disable unsafe functions like 'command' and variables like 'uptime'.
sci-libs/libsc:romio - Build with support for the ROMIO MPI-IO component