gentoo auto-resync : 14:12:2022 - 15:30:24

31 files changed, 90 insertions, 90 deletions

diff --git a/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.2 b/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.2
index 20fe2a2e662e..ba9290fcc7d4 100644
--- a/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.2
+++ b/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.2
@@ -1,4 +1,4 @@
-BDEPEND=dev-python/six[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-libs/numkit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( >=dev-python/pandas-0.17[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) test? ( dev-python/six[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-libs/numkit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) >=dev-python/gpep517-9[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/wheel-0.38.4[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+BDEPEND=dev-python/six[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-libs/numkit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( >=dev-python/pandas-0.17[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) test? ( dev-python/six[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-libs/numkit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/gpep517-9[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/wheel-0.38.4[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DEFINED_PHASES=compile configure install prepare test unpack
 DESCRIPTION=Python framework for Gromacs
 EAPI=7
@@ -7,10 +7,10 @@ INHERIT=distutils-r1 vcs-snapshot
 IUSE=test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-3 LGPL-3
-RDEPEND=dev-python/six[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-libs/numkit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=dev-python/six[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-libs/numkit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/Becksteinlab/GromacsWrapper/archive/release-0.8.2.tar.gz -> GromacsWrapper-0.8.2.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	vcs-snapshot	eab6d8533446763c2e9777d8bbd1594e
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	vcs-snapshot	eab6d8533446763c2e9777d8bbd1594e
 _md5_=eb9831222a6a2a9fb1f7e59d665e6255
diff --git a/metadata/md5-cache/sci-chemistry/MDAnalysis-1.0.0 b/metadata/md5-cache/sci-chemistry/MDAnalysis-1.0.0
index 942a44cad6b4..0e53b3c5238a 100644
--- a/metadata/md5-cache/sci-chemistry/MDAnalysis-1.0.0
+++ b/metadata/md5-cache/sci-chemistry/MDAnalysis-1.0.0
@@ -1,4 +1,4 @@
-BDEPEND=>=dev-python/numpy-1.13.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/netcdf4-python[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/mock[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/duecredit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/six-1.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( >=dev-python/numpy-1.13.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/netcdf4-python[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/mock[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/duecredit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/six-1.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+BDEPEND=>=dev-python/numpy-1.13.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/netcdf4-python[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/mock[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/duecredit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/six-1.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( >=dev-python/numpy-1.13.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/netcdf4-python[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/mock[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/duecredit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/six-1.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DEFINED_PHASES=compile configure install prepare test
 DESCRIPTION=A python library to analyze and manipulate molecular dynamics trajectories
 EAPI=7
@@ -7,10 +7,10 @@ INHERIT=distutils-r1
 IUSE=test test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-2
-RDEPEND=>=dev-python/numpy-1.13.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/netcdf4-python[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/mock[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/duecredit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/six-1.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=>=dev-python/numpy-1.13.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/netcdf4-python[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/mock[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/duecredit[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/six-1.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=mirror://pypi/M/MDAnalysis/MDAnalysis-1.0.0.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=e07b9d991b0ebdc5253eec932ecf80ed
diff --git a/metadata/md5-cache/sci-chemistry/MDAnalysis-2.0.0 b/metadata/md5-cache/sci-chemistry/MDAnalysis-2.0.0
index 57a6559b8fcb..912376410724 100644
--- a/metadata/md5-cache/sci-chemistry/MDAnalysis-2.0.0
+++ b/metadata/md5-cache/sci-chemistry/MDAnalysis-2.0.0
@@ -1,4 +1,4 @@
-BDEPEND=>=dev-python/numpy-1.16.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/threadpoolctl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( >=dev-python/numpy-1.16.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/threadpoolctl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+BDEPEND=>=dev-python/numpy-1.16.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/threadpoolctl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( >=dev-python/numpy-1.16.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/threadpoolctl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DEFINED_PHASES=compile configure install prepare test
 DESCRIPTION=A python library to analyze and manipulate molecular dynamics trajectories
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=distutils-r1
 IUSE=test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-2
-RDEPEND=>=dev-python/numpy-1.16.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/threadpoolctl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=>=dev-python/numpy-1.16.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/scipy-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=sci-biology/biopython-1.71[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/networkx-1.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/GridDataFormats-0.4.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/joblib-0.12[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/matplotlib-1.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/mmtf-python-1.0.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/tqdm-4.43.0[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/gsd-1.9.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/threadpoolctl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=test !test? ( test )
 SLOT=0
 SRC_URI=mirror://pypi/M/MDAnalysis/MDAnalysis-2.0.0.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=ee1c9d9dd59c78af672cdcd2522e7f83
diff --git a/metadata/md5-cache/sci-chemistry/Manifest.gz b/metadata/md5-cache/sci-chemistry/Manifest.gz
index 49d3efa9cd29..c1d487e076ea 100644
--- a/metadata/md5-cache/sci-chemistry/Manifest.gz
+++ b/metadata/md5-cache/sci-chemistry/Manifest.gz
diff --git a/metadata/md5-cache/sci-chemistry/ParmEd-3.4.3 b/metadata/md5-cache/sci-chemistry/ParmEd-3.4.3
index e2abb07763d6..47fb7525dd0f 100644
--- a/metadata/md5-cache/sci-chemistry/ParmEd-3.4.3
+++ b/metadata/md5-cache/sci-chemistry/ParmEd-3.4.3
@@ -1,4 +1,4 @@
-BDEPEND=test? ( >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+BDEPEND=test? ( >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DEFINED_PHASES=compile configure install prepare test
 DESCRIPTION=Parameter and topology file editor and molecular mechanical simulator engine
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=distutils-r1
 IUSE=test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64
 LICENSE=LGPL-2
-RDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/ParmEd/ParmEd/archive/refs/tags/3.4.3.tar.gz -> ParmEd-3.4.3.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=77692821f30ef48205d108cdfb1a6b77
diff --git a/metadata/md5-cache/sci-chemistry/chemex-2022.0.1-r1 b/metadata/md5-cache/sci-chemistry/chemex-2022.0.1-r1
index 35d64c5cd1c4..14f69e1fe6e8 100644
--- a/metadata/md5-cache/sci-chemistry/chemex-2022.0.1-r1
+++ b/metadata/md5-cache/sci-chemistry/chemex-2022.0.1-r1
@@ -1,4 +1,4 @@
-BDEPEND=test? ( python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_9(-)] >=dev-python/numpy-1.23.3[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_9(-)] >=dev-python/rich-12.5.1[python_targets_python3_9(-)] >=dev-python/scipy-1.9.1[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_10(-)] >=dev-python/numpy-1.23.3[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_10(-)] >=dev-python/rich-12.5.1[python_targets_python3_10(-)] >=dev-python/scipy-1.9.1[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] ) python_single_target_python3_9? ( >=dev-python/pytest-7.1.3[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/pytest-7.1.3[python_targets_python3_10(-)] ) ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_9? ( >=dev-python/gpep517-9[python_targets_python3_9(-)] >=dev-python/poetry-core-1.3.2[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/gpep517-9[python_targets_python3_10(-)] >=dev-python/poetry-core-1.3.2[python_targets_python3_10(-)] )
+BDEPEND=test? ( python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_9(-)] >=dev-python/numpy-1.23.3[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_9(-)] >=dev-python/rich-12.5.1[python_targets_python3_9(-)] >=dev-python/scipy-1.9.1[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_10(-)] >=dev-python/numpy-1.23.3[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_10(-)] >=dev-python/rich-12.5.1[python_targets_python3_10(-)] >=dev-python/scipy-1.9.1[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] ) python_single_target_python3_9? ( >=dev-python/pytest-7.1.3[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/pytest-7.1.3[python_targets_python3_10(-)] ) ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_9? ( >=dev-python/gpep517-9[python_targets_python3_9(-)] >=dev-python/poetry-core-1.3.2[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/gpep517-9[python_targets_python3_10(-)] >=dev-python/poetry-core-1.3.2[python_targets_python3_10(-)] )
 DEFINED_PHASES=compile configure install prepare setup test
 DEPEND=python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_9(-)] >=dev-python/numpy-1.23.3[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_9(-)] >=dev-python/rich-12.5.1[python_targets_python3_9(-)] >=dev-python/scipy-1.9.1[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_10(-)] >=dev-python/numpy-1.23.3[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_10(-)] >=dev-python/rich-12.5.1[python_targets_python3_10(-)] >=dev-python/scipy-1.9.1[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] )
 DESCRIPTION=Program to fit chemical exchange induced shift and relaxation data
@@ -8,10 +8,10 @@ INHERIT=distutils-r1
 IUSE=test test python_single_target_python3_9 python_single_target_python3_10
 KEYWORDS=~amd64
 LICENSE=BSD
-RDEPEND=python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_9(-)] >=dev-python/numpy-1.23.3[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_9(-)] >=dev-python/rich-12.5.1[python_targets_python3_9(-)] >=dev-python/scipy-1.9.1[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_10(-)] >=dev-python/numpy-1.23.3[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_10(-)] >=dev-python/rich-12.5.1[python_targets_python3_10(-)] >=dev-python/scipy-1.9.1[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_9(-)] >=dev-python/numpy-1.23.3[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_9(-)] >=dev-python/rich-12.5.1[python_targets_python3_9(-)] >=dev-python/scipy-1.9.1[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.5.3[python_targets_python3_10(-)] >=dev-python/numpy-1.23.3[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.8.0[python_targets_python3_10(-)] >=dev-python/rich-12.5.1[python_targets_python3_10(-)] >=dev-python/scipy-1.9.1[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=^^ ( python_single_target_python3_9 python_single_target_python3_10 )
 RESTRICT=test !test? ( test )
 SLOT=0
 SRC_URI=https://github.com/gbouvignies/ChemEx/archive/refs/tags/v2022.0.1.tar.gz -> chemex-2022.0.1.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=36af9a222bdf212c884b7064d6025a64
diff --git a/metadata/md5-cache/sci-chemistry/chemex-2022.1.0 b/metadata/md5-cache/sci-chemistry/chemex-2022.1.0
index 1d7ead2412ca..2b78ce2a55fa 100644
--- a/metadata/md5-cache/sci-chemistry/chemex-2022.1.0
+++ b/metadata/md5-cache/sci-chemistry/chemex-2022.1.0
@@ -1,4 +1,4 @@
-BDEPEND=test? ( python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_9(-)] >=dev-python/numpy-1.23.4[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_9(-)] >=dev-python/rich-12.6.0[python_targets_python3_9(-)] >=dev-python/scipy-1.9.3[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_10(-)] >=dev-python/numpy-1.23.4[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_10(-)] >=dev-python/rich-12.6.0[python_targets_python3_10(-)] >=dev-python/scipy-1.9.3[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] ) python_single_target_python3_9? ( >=dev-python/pytest-7.1.3[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/pytest-7.1.3[python_targets_python3_10(-)] ) ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_9? ( >=dev-python/gpep517-9[python_targets_python3_9(-)] >=dev-python/poetry-core-1.3.2[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/gpep517-9[python_targets_python3_10(-)] >=dev-python/poetry-core-1.3.2[python_targets_python3_10(-)] )
+BDEPEND=test? ( python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_9(-)] >=dev-python/numpy-1.23.4[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_9(-)] >=dev-python/rich-12.6.0[python_targets_python3_9(-)] >=dev-python/scipy-1.9.3[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_10(-)] >=dev-python/numpy-1.23.4[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_10(-)] >=dev-python/rich-12.6.0[python_targets_python3_10(-)] >=dev-python/scipy-1.9.3[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] ) python_single_target_python3_9? ( >=dev-python/pytest-7.1.3[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/pytest-7.1.3[python_targets_python3_10(-)] ) ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_9? ( >=dev-python/gpep517-9[python_targets_python3_9(-)] >=dev-python/poetry-core-1.3.2[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/gpep517-9[python_targets_python3_10(-)] >=dev-python/poetry-core-1.3.2[python_targets_python3_10(-)] )
 DEFINED_PHASES=compile configure install prepare setup test
 DEPEND=python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_9(-)] >=dev-python/numpy-1.23.4[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_9(-)] >=dev-python/rich-12.6.0[python_targets_python3_9(-)] >=dev-python/scipy-1.9.3[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_10(-)] >=dev-python/numpy-1.23.4[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_10(-)] >=dev-python/rich-12.6.0[python_targets_python3_10(-)] >=dev-python/scipy-1.9.3[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] )
 DESCRIPTION=Program to fit chemical exchange induced shift and relaxation data
@@ -8,10 +8,10 @@ INHERIT=distutils-r1
 IUSE=test test python_single_target_python3_9 python_single_target_python3_10
 KEYWORDS=~amd64
 LICENSE=BSD
-RDEPEND=python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_9(-)] >=dev-python/numpy-1.23.4[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_9(-)] >=dev-python/rich-12.6.0[python_targets_python3_9(-)] >=dev-python/scipy-1.9.3[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_10(-)] >=dev-python/numpy-1.23.4[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_10(-)] >=dev-python/rich-12.6.0[python_targets_python3_10(-)] >=dev-python/scipy-1.9.3[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=python_single_target_python3_9? ( >=dev-python/asteval-0.9.25[python_targets_python3_9(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_9(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_9(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_9(-)] >=dev-python/numpy-1.23.4[python_targets_python3_9(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_9(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_9(-)] >=dev-python/rich-12.6.0[python_targets_python3_9(-)] >=dev-python/scipy-1.9.3[python_targets_python3_9(-)] >=dev-python/tomli-2.0.1[python_targets_python3_9(-)] ) python_single_target_python3_10? ( >=dev-python/asteval-0.9.25[python_targets_python3_10(-)] >=dev-python/cachetools-5.2.0[python_targets_python3_10(-)] >=dev-python/lmfit-1.0.3[python_targets_python3_10(-)] >=dev-python/matplotlib-3.6.1[python_targets_python3_10(-)] >=dev-python/numpy-1.23.4[python_targets_python3_10(-)] >=dev-python/pydantic-1.10.2[python_targets_python3_10(-)] >=dev-python/rapidfuzz-2.11.0[python_targets_python3_10(-)] >=dev-python/rich-12.6.0[python_targets_python3_10(-)] >=dev-python/scipy-1.9.3[python_targets_python3_10(-)] >=dev-python/tomli-2.0.1[python_targets_python3_10(-)] ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=^^ ( python_single_target_python3_9 python_single_target_python3_10 )
 RESTRICT=test !test? ( test )
 SLOT=0
 SRC_URI=https://github.com/gbouvignies/ChemEx/archive/refs/tags/v2022.1.0.tar.gz -> chemex-2022.1.0.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=baa6d065a5d7949a7225fde3814f578a
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2020.4-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2020.4-r1
index e84417f7e4a0..a2238ab4aad6 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2020.4-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2020.4-r1
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=amd64 arm x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2020.4
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2020.4.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2020.4.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2020.4.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	da32ffc285e9f13313f2387570e35b87	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=a9d58ceefb0bc663f763b817d2cd1717
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2020.7 b/metadata/md5-cache/sci-chemistry/gromacs-2020.7
index 2e8e9d0ac734..e4a8dd6fde36 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2020.7
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2020.7
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 ~arm ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2020.7
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2020.7.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2020.7.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2020.7.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	da32ffc285e9f13313f2387570e35b87	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=a9dec67c45cdabcd7dd00665d56788ef
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1
index 953173ade367..8b3c86876f20 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=amd64 arm x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2021.3
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2021.3.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2021.3.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2021.3.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	da32ffc285e9f13313f2387570e35b87	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=98427c2d71209dc2b36430f4e63099a7
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.5 b/metadata/md5-cache/sci-chemistry/gromacs-2021.5
index 4762dcb0a86d..41fd1bee5d22 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.5
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.5
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 ~arm ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2021.5
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2021.5.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2021.5.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2021.5.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	da32ffc285e9f13313f2387570e35b87	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=2b77d90efe779b2dc01a0b4a2a4fc950
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.6 b/metadata/md5-cache/sci-chemistry/gromacs-2021.6
index 1f89c1fc3a3a..22688097ff75 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.6
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.6
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 ~arm ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2021.6
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2021.6.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2021.6.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2021.6.tar.gz )
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 _md5_=2b77d90efe779b2dc01a0b4a2a4fc950
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.9999 b/metadata/md5-cache/sci-chemistry/gromacs-2021.9999
index b103e982beab..457537cfdec7 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.9999
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,9 +7,9 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
 PROPERTIES=live
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2021.9999
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	da32ffc285e9f13313f2387570e35b87	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=37783db6fed45127d7398fa432dec03d
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.2 b/metadata/md5-cache/sci-chemistry/gromacs-2022.2
index 3d2b0e52b121..3fa447598932 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.2
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2022.2
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=blas clang clang-cuda cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 -arm ~arm64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2022.2
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2022.2.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2022.2.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2022.2.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	da32ffc285e9f13313f2387570e35b87	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=6017ac56695990e60fa079e1286c7ba4
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.3 b/metadata/md5-cache/sci-chemistry/gromacs-2022.3
index 5ad6781c160c..0a4b6a3d45f6 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.3
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2022.3
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=blas clang clang-cuda cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 -arm ~arm64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2022.3
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2022.3.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2022.3.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2022.3.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	da32ffc285e9f13313f2387570e35b87	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=6017ac56695990e60fa079e1286c7ba4
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.9999 b/metadata/md5-cache/sci-chemistry/gromacs-2022.9999
index d3d3431c52c6..db3bdaabf899 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2022.9999
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,9 +7,9 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
 PROPERTIES=live
-RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2022.9999
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	da32ffc285e9f13313f2387570e35b87	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=763d089738fde7ef4f9fa28e4e523094
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-9999 b/metadata/md5-cache/sci-chemistry/gromacs-9999
index ab1510b6d853..bc156e5c1fe0 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-9999
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,9 +7,9 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
 PROPERTIES=live
-RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/9999
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	da32ffc285e9f13313f2387570e35b87	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=763d089738fde7ef4f9fa28e4e523094
diff --git a/metadata/md5-cache/sci-chemistry/mdtraj-1.9.4 b/metadata/md5-cache/sci-chemistry/mdtraj-1.9.4
index d434068afefc..83a4cd1de70f 100644
--- a/metadata/md5-cache/sci-chemistry/mdtraj-1.9.4
+++ b/metadata/md5-cache/sci-chemistry/mdtraj-1.9.4
@@ -1,4 +1,4 @@
-BDEPEND=test? ( dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?]
+BDEPEND=test? ( dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?]
 DEFINED_PHASES=compile configure install prepare test
 DEPEND=dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] test? ( dev-python/jupyter_client[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/nbformat[python_targets_python3_8(-)?,python_targets_python3_9(-)?] )
 DESCRIPTION=Read, write and analyze MD trajectories with only a few lines of Python code
@@ -8,10 +8,10 @@ INHERIT=distutils-r1
 IUSE=test python_targets_python3_8 python_targets_python3_9
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=LGPL-2.1+
-RDEPEND=dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 )
+RDEPEND=dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 )
 RESTRICT=test
 SLOT=0
 SRC_URI=mirror://pypi/m/mdtraj/mdtraj-1.9.4.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=621472da0f799a837b582ddd6dab5396
diff --git a/metadata/md5-cache/sci-chemistry/mdtraj-1.9.7 b/metadata/md5-cache/sci-chemistry/mdtraj-1.9.7
index f9265f0b1392..d16b6d8709b3 100644
--- a/metadata/md5-cache/sci-chemistry/mdtraj-1.9.7
+++ b/metadata/md5-cache/sci-chemistry/mdtraj-1.9.7
@@ -1,4 +1,4 @@
-BDEPEND=test? ( dev-python/astunparse[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pyparsing[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+BDEPEND=test? ( dev-python/astunparse[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pyparsing[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DEFINED_PHASES=compile configure install prepare test
 DEPEND=dev-python/astunparse[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pyparsing[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( dev-python/ipykernel[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/jupyter_client[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/nbformat[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-libs/scikit-learn[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] )
 DESCRIPTION=Read, write and analyze MD trajectories with only a few lines of Python code
@@ -8,10 +8,10 @@ INHERIT=distutils-r1
 IUSE=test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=LGPL-2.1+
-RDEPEND=dev-python/astunparse[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pyparsing[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=dev-python/astunparse[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/astor[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pytables[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pyparsing[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=mirror://pypi/m/mdtraj/mdtraj-1.9.7.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=80c9f058ec0514165bed45017d07dd62
diff --git a/metadata/md5-cache/sci-chemistry/modeller-9.25 b/metadata/md5-cache/sci-chemistry/modeller-9.25
index 72f44c927bd6..6034a180d82f 100644
--- a/metadata/md5-cache/sci-chemistry/modeller-9.25
+++ b/metadata/md5-cache/sci-chemistry/modeller-9.25
@@ -1,4 +1,4 @@
-BDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+BDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 DEFINED_PHASES=compile config configure install postinst postrm prepare setup test
 DEPEND=>=dev-lang/swig-1.3
 DESCRIPTION=Homology or comparative modeling of protein three-dimensional structures
@@ -8,10 +8,10 @@ INHERIT=distutils-r1
 IUSE=doc examples python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=modeller
-RDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=mirror
 SLOT=0
 SRC_URI=https://salilab.org/modeller/9.25/modeller-9.25.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=b95991329a6a5e37067102edc03fc9c6
diff --git a/metadata/md5-cache/sci-chemistry/molequeue-0.9.0-r1 b/metadata/md5-cache/sci-chemistry/molequeue-0.9.0-r1
index 7356c5b215e3..9c855e43364a 100644
--- a/metadata/md5-cache/sci-chemistry/molequeue-0.9.0-r1
+++ b/metadata/md5-cache/sci-chemistry/molequeue-0.9.0-r1
@@ -1,6 +1,6 @@
 BDEPEND=doc? ( app-doc/doxygen ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 test? ( x11-base/xorg-server[xvfb] x11-apps/xhost )
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtwidgets:5 zeromq? ( python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) net-libs/cppzmq:0= )
+DEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtwidgets:5 zeromq? ( python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) net-libs/cppzmq:0= )
 DESCRIPTION=Abstract, manage and coordinate execution of tasks
 EAPI=7
 HOMEPAGE=https://www.openchemistry.org/projects/molequeue/
@@ -8,10 +8,10 @@ INHERIT=cmake python-r1 virtualx
 IUSE=+client doc server test +zeromq python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 python_targets_python3_11 test
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=BSD
-RDEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtwidgets:5 zeromq? ( python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) net-libs/cppzmq:0= )
+RDEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtwidgets:5 zeromq? ( python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) net-libs/cppzmq:0= )
 REQUIRED_USE=server? ( client ) test? ( server ) zeromq? ( || ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 python_targets_python3_11 ) )
 RESTRICT=test
 SLOT=0
 SRC_URI=https://github.com/OpenChemistry/molequeue/archive/0.9.0.tar.gz -> molequeue-0.9.0.tar.gz
-_eclasses_=cmake	646b7a2a63596361551a6c1fabf28057	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	virtualx	644887c82aefdf12001489391fca4f02	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=cmake	646b7a2a63596361551a6c1fabf28057	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	virtualx	644887c82aefdf12001489391fca4f02	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=c514f6a40aa78786545cbc221f21ade3
diff --git a/metadata/md5-cache/sci-chemistry/nmrglue-0.7 b/metadata/md5-cache/sci-chemistry/nmrglue-0.7
index fe5f3acdaf78..a9e901396e82 100644
--- a/metadata/md5-cache/sci-chemistry/nmrglue-0.7
+++ b/metadata/md5-cache/sci-chemistry/nmrglue-0.7
@@ -1,4 +1,4 @@
-BDEPEND=test? ( dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_8(-)?,python_targets_python3_9(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?]
+BDEPEND=test? ( dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_8(-)?,python_targets_python3_9(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?]
 DEFINED_PHASES=compile configure install prepare test
 DEPEND=dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?]
 DESCRIPTION=A module for working with NMR data in Python
@@ -8,10 +8,10 @@ INHERIT=distutils-r1
 IUSE=test python_targets_python3_8 python_targets_python3_9
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=BSD
-RDEPEND=dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 )
+RDEPEND=dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/jjhelmus/nmrglue/releases/download/v0.7/nmrglue-0.7.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=197459a7eef5261de4cf3cb0315254ac
diff --git a/metadata/md5-cache/sci-chemistry/nmrglue-0.9 b/metadata/md5-cache/sci-chemistry/nmrglue-0.9
index df4604db8fc4..3916cdcb9373 100644
--- a/metadata/md5-cache/sci-chemistry/nmrglue-0.9
+++ b/metadata/md5-cache/sci-chemistry/nmrglue-0.9
@@ -1,4 +1,4 @@
-BDEPEND=test? ( app-shells/tcsh ) test? ( dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) doc? ( || ( ( >=dev-lang/python-3.10.8_p3:3.10 >=dev-python/sphinx-5.3.0[python_targets_python3_10(-)] dev-python/sphinx_rtd_theme[python_targets_python3_10(-)] dev-python/numpydoc[python_targets_python3_10(-)] ) ( >=dev-lang/python-3.9.15_p3:3.9 >=dev-python/sphinx-5.3.0[python_targets_python3_9(-)] dev-python/sphinx_rtd_theme[python_targets_python3_9(-)] dev-python/numpydoc[python_targets_python3_9(-)] ) ( >=dev-lang/python-3.8.15_p3:3.8 >=dev-python/sphinx-5.3.0[python_targets_python3_8(-)] dev-python/sphinx_rtd_theme[python_targets_python3_8(-)] dev-python/numpydoc[python_targets_python3_8(-)] ) ) ) python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) >=dev-python/gpep517-9[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/wheel-0.38.4[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+BDEPEND=test? ( app-shells/tcsh ) test? ( dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) doc? ( || ( ( >=dev-lang/python-3.10.9:3.10 >=dev-python/sphinx-5.3.0[python_targets_python3_10(-)] dev-python/sphinx_rtd_theme[python_targets_python3_10(-)] dev-python/numpydoc[python_targets_python3_10(-)] ) ( >=dev-lang/python-3.9.16:3.9 >=dev-python/sphinx-5.3.0[python_targets_python3_9(-)] dev-python/sphinx_rtd_theme[python_targets_python3_9(-)] dev-python/numpydoc[python_targets_python3_9(-)] ) ( >=dev-lang/python-3.8.16:3.8 >=dev-python/sphinx-5.3.0[python_targets_python3_8(-)] dev-python/sphinx_rtd_theme[python_targets_python3_8(-)] dev-python/numpydoc[python_targets_python3_8(-)] ) ) ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/gpep517-9[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/wheel-0.38.4[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DEFINED_PHASES=compile configure install prepare test
 DEPEND=dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DESCRIPTION=A module for working with NMR data in Python
@@ -8,10 +8,10 @@ INHERIT=distutils-r1
 IUSE=test doc python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=BSD
-RDEPEND=dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=test !test? ( test )
 SLOT=0
 SRC_URI=https://github.com/jjhelmus/nmrglue/archive/v0.9.tar.gz -> nmrglue-0.9.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=d295ede89b0452cc2f4fe73e43e8b492
diff --git a/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225 b/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225
index 4a39fe39426f..d910c3367c51 100644
--- a/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225
+++ b/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225
@@ -1,6 +1,6 @@
 BDEPEND=dev-lang/perl doc? ( app-doc/doxygen dev-texlive/texlive-latex ) perl? ( >=dev-lang/swig-2 ) python? ( >=dev-lang/swig-2 ) test? ( dev-lang/python ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst postrm prepare pretend setup test
-DEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) ) wxwidgets? ( x11-libs/wxGTK:3.0-gtk3[X] ) perl? ( dev-lang/perl )
+DEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) ) wxwidgets? ( x11-libs/wxGTK:3.0-gtk3[X] ) perl? ( dev-lang/perl )
 DESCRIPTION=Interconverts file formats used in molecular modeling
 EAPI=8
 HOMEPAGE=https://openbabel.org/
@@ -8,10 +8,10 @@ INHERIT=cmake desktop flag-o-matic perl-functions python-r1 toolchain-funcs wxwi
 IUSE=cpu_flags_arm_neon cpu_flags_x86_sse2 cpu_flags_x86_sse4_2 doc examples +inchi json minimal openmp perl png python test wxwidgets python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=amd64 ~arm x86 ~amd64-linux ~x86-linux ~ppc-macos
 LICENSE=GPL-2
-RDEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) ) wxwidgets? ( x11-libs/wxGTK:3.0-gtk3[X] ) perl? ( dev-lang/perl:= !sci-chemistry/openbabel-perl )
+RDEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) ) wxwidgets? ( x11-libs/wxGTK:3.0-gtk3[X] ) perl? ( dev-lang/perl:= !sci-chemistry/openbabel-perl )
 REQUIRED_USE=python? ( || ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 ) ) test? ( inchi json !minimal wxwidgets )
 RESTRICT=!test? ( test )
 SLOT=0/7.0.0
 SRC_URI=https://github.com/openbabel/openbabel/archive/08e23f39b0cc39b4eebd937a5a2ffc1a7bac3e1b.tar.gz -> openbabel-3.1.1_p20210225.tar.gz https://openbabel.org/docs/dev/_static/babel130.png -> openbabel.png http://openbabel.org/OBTitle.jpg -> openbabel.jpg
-_eclasses_=cmake	646b7a2a63596361551a6c1fabf28057	desktop	7eb20ad915a0a318176d51bc2508ff5c	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wxwidgets	c09e9b94378cadaf6ef86ec1534c0fd6	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=cmake	646b7a2a63596361551a6c1fabf28057	desktop	7eb20ad915a0a318176d51bc2508ff5c	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wxwidgets	c09e9b94378cadaf6ef86ec1534c0fd6	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=219030e81d976d743129dc077888bef8
diff --git a/metadata/md5-cache/sci-chemistry/openbabel-9999 b/metadata/md5-cache/sci-chemistry/openbabel-9999
index 40c2f759ede3..763e7f83e912 100644
--- a/metadata/md5-cache/sci-chemistry/openbabel-9999
+++ b/metadata/md5-cache/sci-chemistry/openbabel-9999
@@ -1,6 +1,6 @@
 BDEPEND=dev-lang/perl doc? ( app-doc/doxygen dev-texlive/texlive-latex ) perl? ( >=dev-lang/swig-2 ) python? ( >=dev-lang/swig-2 ) test? ( dev-lang/python ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst postrm prepare pretend setup test unpack
-DEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) ) wxwidgets? ( x11-libs/wxGTK:3.0-gtk3[X] ) perl? ( dev-lang/perl )
+DEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) ) wxwidgets? ( x11-libs/wxGTK:3.0-gtk3[X] ) perl? ( dev-lang/perl )
 DESCRIPTION=Interconverts file formats used in molecular modeling
 EAPI=8
 HOMEPAGE=https://openbabel.org/
@@ -8,10 +8,10 @@ INHERIT=cmake desktop flag-o-matic perl-functions python-r1 toolchain-funcs wxwi
 IUSE=cpu_flags_arm_neon cpu_flags_x86_sse2 cpu_flags_x86_sse4_2 doc examples +inchi json minimal openmp perl png python test wxwidgets python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 LICENSE=GPL-2
 PROPERTIES=live
-RDEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) ) wxwidgets? ( x11-libs/wxGTK:3.0-gtk3[X] ) perl? ( dev-lang/perl:= !sci-chemistry/openbabel-perl )
+RDEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) ) wxwidgets? ( x11-libs/wxGTK:3.0-gtk3[X] ) perl? ( dev-lang/perl:= !sci-chemistry/openbabel-perl )
 REQUIRED_USE=python? ( || ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 ) ) test? ( inchi json !minimal wxwidgets )
 RESTRICT=!test? ( test )
 SLOT=0/7.0.0
 SRC_URI=https://openbabel.org/docs/dev/_static/babel130.png -> openbabel.png http://openbabel.org/OBTitle.jpg -> openbabel.jpg
-_eclasses_=cmake	646b7a2a63596361551a6c1fabf28057	desktop	7eb20ad915a0a318176d51bc2508ff5c	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wxwidgets	c09e9b94378cadaf6ef86ec1534c0fd6	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=cmake	646b7a2a63596361551a6c1fabf28057	desktop	7eb20ad915a0a318176d51bc2508ff5c	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wxwidgets	c09e9b94378cadaf6ef86ec1534c0fd6	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=b125d73885867c3083da967d79d004a0
diff --git a/metadata/md5-cache/sci-chemistry/propka-3.4.0 b/metadata/md5-cache/sci-chemistry/propka-3.4.0
index 9951f2649529..302fdc6b721a 100644
--- a/metadata/md5-cache/sci-chemistry/propka-3.4.0
+++ b/metadata/md5-cache/sci-chemistry/propka-3.4.0
@@ -1,4 +1,4 @@
-BDEPEND=test? ( dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 ) >=dev-python/gpep517-9[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] >=dev-python/setuptools-65.5.1[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] >=dev-python/wheel-0.38.4[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?]
+BDEPEND=test? ( dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) >=dev-python/gpep517-9[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] >=dev-python/setuptools-65.5.1[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] >=dev-python/wheel-0.38.4[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?]
 DEFINED_PHASES=compile configure install prepare test
 DESCRIPTION=pKa-value prediction of ionizable groups in protein and protein-ligand complexes
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=distutils-r1
 IUSE=test python_targets_python3_9 python_targets_python3_10 python_targets_python3_11
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=LGPL-2.1
-RDEPEND=dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.0_p2:3.11 )
+RDEPEND=dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 REQUIRED_USE=|| ( python_targets_python3_9 python_targets_python3_10 python_targets_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/jensengroup/propka/archive/refs/tags/v3.4.0.tar.gz -> propka-3.4.0.gh.tar.gz
-_eclasses_=distutils-r1	da32ffc285e9f13313f2387570e35b87	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
+_eclasses_=distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491
 _md5_=df9c2734ddc4d3199b2a42247a6a9496
diff --git a/metadata/md5-cache/sci-chemistry/pymol-2.5.0 b/metadata/md5-cache/sci-chemistry/pymol-2.5.0
index d6c7148c19c9..c611c0d430dd 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-2.5.0
+++ b/metadata/md5-cache/sci-chemistry/pymol-2.5.0
@@ -1,4 +1,4 @@
-BDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+BDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 DEFINED_PHASES=compile configure install postinst postrm preinst prepare test
 DEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp dev-python/pyopengl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/PyQt5[opengl,python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pmw[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib netcdf? ( sci-libs/netcdf:0= ) dev-util/desktop-file-utils x11-misc/shared-mime-info
 DESCRIPTION=A Python-extensible molecular graphics system
@@ -8,10 +8,10 @@ INHERIT=desktop flag-o-matic xdg distutils-r1
 IUSE=+netcdf web python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=PSF-2.2
-RDEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp dev-python/pyopengl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/PyQt5[opengl,python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pmw[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib netcdf? ( sci-libs/netcdf:0= ) sci-chemistry/chemical-mime-data python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp dev-python/pyopengl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/PyQt5[opengl,python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pmw[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib netcdf? ( sci-libs/netcdf:0= ) sci-chemistry/chemical-mime-data python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=mirror
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~pacho/pymol/pymol-1.8.4.0.png.xz https://github.com/schrodinger/pymol-open-source/archive/v2.5.0.tar.gz -> pymol-2.5.0.tar.gz
-_eclasses_=desktop	7eb20ad915a0a318176d51bc2508ff5c	distutils-r1	da32ffc285e9f13313f2387570e35b87	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg	6024fbc93167fad782e2032933654857	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=desktop	7eb20ad915a0a318176d51bc2508ff5c	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg	6024fbc93167fad782e2032933654857	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=7bb4d93e554e41f93f1e3959c541e38c
diff --git a/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r1 b/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r1
index 4aeb0129a6ec..199718578b25 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r1
+++ b/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r1
@@ -1,4 +1,4 @@
-BDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+BDEPEND=python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 DEFINED_PHASES=compile configure install postinst postrm preinst prepare test
 DEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp dev-python/pyopengl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/PyQt5[opengl,python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pmw[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib netcdf? ( sci-libs/netcdf:0= )
 DESCRIPTION=A Python-extensible molecular graphics system
@@ -9,9 +9,9 @@ INHERIT=desktop flag-o-matic xdg distutils-r1
 IUSE=+netcdf web python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=BitstreamVera BSD freedist HPND OFL public-domain UoI-NCSA
-RDEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp dev-python/pyopengl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/PyQt5[opengl,python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pmw[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib netcdf? ( sci-libs/netcdf:0= ) sci-chemistry/chemical-mime-data python_targets_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 )
+RDEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp dev-python/pyopengl[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/PyQt5[opengl,python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pmw[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib netcdf? ( sci-libs/netcdf:0= ) sci-chemistry/chemical-mime-data python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~pacho/pymol/pymol-1.8.4.0.png.xz https://github.com/schrodinger/pymol-open-source/archive/v2.5.0.tar.gz -> pymol-2.5.0.tar.gz
-_eclasses_=desktop	7eb20ad915a0a318176d51bc2508ff5c	distutils-r1	da32ffc285e9f13313f2387570e35b87	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg	6024fbc93167fad782e2032933654857	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=desktop	7eb20ad915a0a318176d51bc2508ff5c	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-r1	2d51fd03931e743811ce30d198e4dcfd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg	6024fbc93167fad782e2032933654857	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=8320b4b690e8f97a7400d54894534d09
diff --git a/metadata/md5-cache/sci-chemistry/vmd-1.9.4_alpha57 b/metadata/md5-cache/sci-chemistry/vmd-1.9.4_alpha57
index addb26e5d49a..a6c2e63ef192 100644
--- a/metadata/md5-cache/sci-chemistry/vmd-1.9.4_alpha57
+++ b/metadata/md5-cache/sci-chemistry/vmd-1.9.4_alpha57
@@ -1,6 +1,6 @@
 BDEPEND=virtual/pkgconfig dev-lang/swig
 DEFINED_PHASES=compile configure install nofetch postinst postrm preinst prepare setup
-DEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_8? ( dev-python/numpy[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/numpy[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/numpy[python_targets_python3_10(-)] ) >=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama )
+DEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_8? ( dev-python/numpy[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/numpy[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/numpy[python_targets_python3_10(-)] ) >=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama )
 DESCRIPTION=Visual Molecular Dynamics
 EAPI=8
 HOMEPAGE=http://www.ks.uiuc.edu/Research/vmd/
@@ -9,10 +9,10 @@ INHERIT=cuda desktop flag-o-matic prefix python-single-r1 toolchain-funcs xdg
 IUSE=cuda gromacs msms povray sqlite tachyon xinerama python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=vmd
-RDEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) python_single_target_python3_8? ( dev-python/numpy[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/numpy[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/numpy[python_targets_python3_10(-)] ) >=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/chemical-mime-data sci-chemistry/surf x11-misc/xdg-utils x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
+RDEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_8? ( dev-python/numpy[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/numpy[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/numpy[python_targets_python3_10(-)] ) >=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/chemical-mime-data sci-chemistry/surf x11-misc/xdg-utils x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
 REQUIRED_USE=^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 )
 RESTRICT=fetch
 SLOT=0
 SRC_URI=vmd-1.9.4a57.src.tar.gz fetch+https://dev.gentoo.org/~pacho/vmd/vmd-1.9.4_alpha57-gentoo-patches.tar.xz
-_eclasses_=cuda	bbef1902e3953ff9f3a9947ebf4e56f9	desktop	7eb20ad915a0a318176d51bc2508ff5c	flag-o-matic	69394e25812406faa1f90edaf4969395	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	prefix	eab3c99d77fe00506c109c8a736186f7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg	6024fbc93167fad782e2032933654857	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=cuda	bbef1902e3953ff9f3a9947ebf4e56f9	desktop	7eb20ad915a0a318176d51bc2508ff5c	flag-o-matic	69394e25812406faa1f90edaf4969395	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	prefix	eab3c99d77fe00506c109c8a736186f7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	xdg	6024fbc93167fad782e2032933654857	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=2bbc8350e0b2d9da91e7e20f2c26fbf0
diff --git a/metadata/md5-cache/sci-chemistry/votca-2022 b/metadata/md5-cache/sci-chemistry/votca-2022
index 76c39bf4169b..f312537867e9 100644
--- a/metadata/md5-cache/sci-chemistry/votca-2022
+++ b/metadata/md5-cache/sci-chemistry/votca-2022
@@ -1,6 +1,6 @@
 BDEPEND=virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare setup test
-DEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
+DEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
 DESCRIPTION=Versatile Object-oriented Toolkit for Coarse-graining Applications
 EAPI=7
 HOMEPAGE=https://www.votca.org/
@@ -8,10 +8,10 @@ INHERIT=bash-completion-r1 cmake python-single-r1
 IUSE=+gromacs test python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10
 KEYWORDS=amd64 x86 ~amd64-linux
 LICENSE=Apache-2.0
-RDEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
+RDEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
 REQUIRED_USE=^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/votca/votca/archive/v2022.tar.gz -> votca-2022.tar.gz
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	ac0e315a3688929e34ac75b139e7349a
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	6a75203e8a499f0fb42971452ce15388	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	ac0e315a3688929e34ac75b139e7349a
 _md5_=715c58a911a5aa30ab5e914b627a036d
diff --git a/metadata/md5-cache/sci-chemistry/votca-9999 b/metadata/md5-cache/sci-chemistry/votca-9999
index 4b6b526cc1dd..82be290b83e4 100644
--- a/metadata/md5-cache/sci-chemistry/votca-9999
+++ b/metadata/md5-cache/sci-chemistry/votca-9999
@@ -1,6 +1,6 @@
 BDEPEND=virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare setup test unpack
-DEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
+DEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
 DESCRIPTION=Versatile Object-oriented Toolkit for Coarse-graining Applications
 EAPI=7
 HOMEPAGE=https://www.votca.org/
@@ -8,9 +8,9 @@ INHERIT=bash-completion-r1 cmake python-single-r1 git-r3
 IUSE=+gromacs test python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10
 LICENSE=Apache-2.0
 PROPERTIES=live
-RDEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_8? ( >=dev-lang/python-3.8.15_p3:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.15_p3:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.8_p3:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
+RDEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
 REQUIRED_USE=^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 )
 RESTRICT=!test? ( test )
 SLOT=0
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	646b7a2a63596361551a6c1fabf28057	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	25c880c1db58e21b80b684bacc964958	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	ac0e315a3688929e34ac75b139e7349a
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 _md5_=fa681690dc7c4904899bd6807e2ca434