gentoo auto-resync : 15:12:2023 - 08:46:53

43 files changed, 72 insertions, 72 deletions

diff --git a/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.4 b/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.4
index 470b82916187..27487ebd8a67 100644
--- a/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.4
+++ b/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.4
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( python_targets_python3_10 python_targets_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/Becksteinlab/GromacsWrapper/archive/release-0.8.4.tar.gz -> GromacsWrapper-0.8.4.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	vcs-snapshot	eab6d8533446763c2e9777d8bbd1594e
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	vcs-snapshot	eab6d8533446763c2e9777d8bbd1594e
 _md5_=186a2e983e24b6f2de6e21319f4678d0
diff --git a/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.5 b/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.5
index 0d0d0846d278..7d910a542b37 100644
--- a/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.5
+++ b/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.5
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( python_targets_python3_10 python_targets_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/Becksteinlab/GromacsWrapper/archive/release-0.8.5.tar.gz -> GromacsWrapper-0.8.5.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	vcs-snapshot	eab6d8533446763c2e9777d8bbd1594e
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	vcs-snapshot	eab6d8533446763c2e9777d8bbd1594e
 _md5_=186a2e983e24b6f2de6e21319f4678d0
diff --git a/metadata/md5-cache/sci-chemistry/MDAnalysis-2.6.1 b/metadata/md5-cache/sci-chemistry/MDAnalysis-2.6.1
index 4f3df4b8036f..7e32680f101c 100644
--- a/metadata/md5-cache/sci-chemistry/MDAnalysis-2.6.1
+++ b/metadata/md5-cache/sci-chemistry/MDAnalysis-2.6.1
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( python_targets_python3_10 python_targets_python3_11 )
 RESTRICT=test !test? ( test )
 SLOT=0
 SRC_URI=https://files.pythonhosted.org/packages/source/M/MDAnalysis/MDAnalysis-2.6.1.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	pypi	2eecb475512bc76e5ea9192a681b9e6b	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	pypi	2eecb475512bc76e5ea9192a681b9e6b	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
 _md5_=84dc6666e8c03adb1bb3340b1d1b52f9
diff --git a/metadata/md5-cache/sci-chemistry/Manifest.gz b/metadata/md5-cache/sci-chemistry/Manifest.gz
index 46a632dbdd91..d2adaa7e2403 100644
--- a/metadata/md5-cache/sci-chemistry/Manifest.gz
+++ b/metadata/md5-cache/sci-chemistry/Manifest.gz
diff --git a/metadata/md5-cache/sci-chemistry/ParmEd-3.4.3 b/metadata/md5-cache/sci-chemistry/ParmEd-3.4.3
index aadd62727a1f..855b218a169d 100644
--- a/metadata/md5-cache/sci-chemistry/ParmEd-3.4.3
+++ b/metadata/md5-cache/sci-chemistry/ParmEd-3.4.3
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( python_targets_python3_10 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/ParmEd/ParmEd/archive/refs/tags/3.4.3.tar.gz -> ParmEd-3.4.3.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
 _md5_=9c159ea6d08a10ebaa436af52e048001
diff --git a/metadata/md5-cache/sci-chemistry/avogadro2-1.95.1 b/metadata/md5-cache/sci-chemistry/avogadro2-1.95.1
index b812e750b64e..7ad2cac54d1f 100644
--- a/metadata/md5-cache/sci-chemistry/avogadro2-1.95.1
+++ b/metadata/md5-cache/sci-chemistry/avogadro2-1.95.1
@@ -1,4 +1,4 @@
-BDEPEND=doc? ( app-doc/doxygen media-gfx/graphviz ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=doc? ( app-doc/doxygen media-gfx/graphviz ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst postrm preinst prepare test unpack
 DEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtwidgets:5 >=sci-libs/avogadrolibs-1.95.1[qt5,vtk?] sci-libs/hdf5:= rpc? ( sci-chemistry/molequeue ) dev-cpp/eigen:3 test? ( dev-qt/qttest:5 )
 DESCRIPTION=Advanced molecule editor and visualizer 2
@@ -13,5 +13,5 @@ RDEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtwidgets:5 >=sci-libs/avogadrolib
 RESTRICT=test
 SLOT=0
 SRC_URI=https://github.com/OpenChemistry/avogadroapp/archive/1.95.1.tar.gz -> avogadro2-1.95.1.tar.gz https://github.com/OpenChemistry/avogadro-i18n/archive/3b8a86cc37e988b043d1503d2f11068389b0aca3.tar.gz -> avogadro2-1.95.1-i18n.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	docs	74475974eae5130ba3e19b31b8ae46b8	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	docs	74475974eae5130ba3e19b31b8ae46b8	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=63852b6e1a0d593b6df49dc2b1b457f0
diff --git a/metadata/md5-cache/sci-chemistry/avogadro2-1.97.0 b/metadata/md5-cache/sci-chemistry/avogadro2-1.97.0
index 807a14f0afe9..9698930d793f 100644
--- a/metadata/md5-cache/sci-chemistry/avogadro2-1.97.0
+++ b/metadata/md5-cache/sci-chemistry/avogadro2-1.97.0
@@ -1,4 +1,4 @@
-BDEPEND=doc? ( app-doc/doxygen media-gfx/graphviz ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=doc? ( app-doc/doxygen media-gfx/graphviz ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst postrm preinst prepare test unpack
 DEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtwidgets:5 >=sci-libs/avogadrolibs-1.97.0[qt5,vtk?] sci-libs/hdf5:= rpc? ( sci-chemistry/molequeue ) dev-cpp/eigen:3 test? ( dev-qt/qttest:5 )
 DESCRIPTION=Advanced molecule editor and visualizer 2
@@ -13,5 +13,5 @@ RDEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtwidgets:5 >=sci-libs/avogadrolib
 RESTRICT=test
 SLOT=0
 SRC_URI=https://github.com/OpenChemistry/avogadroapp/archive/1.97.0.tar.gz -> avogadro2-1.97.0.tar.gz https://github.com/OpenChemistry/avogadro-i18n/archive/13c4286102373658cea48a33b86536ab5793da66.tar.gz -> avogadro2-1.97.0-i18n.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	docs	74475974eae5130ba3e19b31b8ae46b8	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	docs	74475974eae5130ba3e19b31b8ae46b8	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=4d16d471e4fb5d4f76219007401eda51
diff --git a/metadata/md5-cache/sci-chemistry/chemex-2022.3.5 b/metadata/md5-cache/sci-chemistry/chemex-2022.3.5
index 497b5776412d..aff459ad5864 100644
--- a/metadata/md5-cache/sci-chemistry/chemex-2022.3.5
+++ b/metadata/md5-cache/sci-chemistry/chemex-2022.3.5
@@ -13,5 +13,5 @@ REQUIRED_USE=^^ ( python_single_target_python3_10 python_single_target_python3_1
 RESTRICT=test !test? ( test )
 SLOT=0
 SRC_URI=https://github.com/gbouvignies/ChemEx/archive/refs/tags/v2022.3.5.tar.gz -> chemex-2022.3.5.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
 _md5_=dbb860f5a52f998720d27b1ad83813ad
diff --git a/metadata/md5-cache/sci-chemistry/chemex-2022.3.6 b/metadata/md5-cache/sci-chemistry/chemex-2022.3.6
index fd1a7063e312..f0370ccb50e8 100644
--- a/metadata/md5-cache/sci-chemistry/chemex-2022.3.6
+++ b/metadata/md5-cache/sci-chemistry/chemex-2022.3.6
@@ -13,5 +13,5 @@ REQUIRED_USE=^^ ( python_single_target_python3_10 python_single_target_python3_1
 RESTRICT=test !test? ( test )
 SLOT=0
 SRC_URI=https://github.com/gbouvignies/ChemEx/archive/refs/tags/2022.3.6.tar.gz -> chemex-2022.3.6.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
 _md5_=af51d45d9331818222891465aa44fac4
diff --git a/metadata/md5-cache/sci-chemistry/dssp-4.3.1 b/metadata/md5-cache/sci-chemistry/dssp-4.3.1
index dc51b1915cbf..92b8dbc134eb 100644
--- a/metadata/md5-cache/sci-chemistry/dssp-4.3.1
+++ b/metadata/md5-cache/sci-chemistry/dssp-4.3.1
@@ -1,4 +1,4 @@
-BDEPEND=dev-libs/boost:=[zlib] >=dev-libs/libmcfp-1.2.2 >=sci-libs/libcifpp-5.1.0 >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=dev-libs/boost:=[zlib] >=dev-libs/libmcfp-1.2.2 >=sci-libs/libcifpp-5.1.0 app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare test
 DESCRIPTION=The protein secondary structure standard
 EAPI=8
@@ -9,5 +9,5 @@ LICENSE=BSD-2
 RDEPEND=dev-libs/boost:=[zlib] >=dev-libs/libmcfp-1.2.2 >=sci-libs/libcifpp-5.1.0
 SLOT=0
 SRC_URI=https://github.com/PDB-REDO/dssp/archive/refs/tags/v4.3.1.tar.gz -> dssp-4.3.1.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=20e3c936771622d32f440399727f136c
diff --git a/metadata/md5-cache/sci-chemistry/dssp-4.4.1 b/metadata/md5-cache/sci-chemistry/dssp-4.4.1
index 69d6008fed5a..e03f66c0f00a 100644
--- a/metadata/md5-cache/sci-chemistry/dssp-4.4.1
+++ b/metadata/md5-cache/sci-chemistry/dssp-4.4.1
@@ -1,4 +1,4 @@
-BDEPEND=dev-libs/boost:=[zlib] >=dev-libs/libmcfp-1.2.2 >=sci-libs/libcifpp-5.1.0 >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=dev-libs/boost:=[zlib] >=dev-libs/libmcfp-1.2.2 >=sci-libs/libcifpp-5.1.0 app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare test
 DESCRIPTION=The protein secondary structure standard
 EAPI=8
@@ -9,5 +9,5 @@ LICENSE=BSD-2
 RDEPEND=dev-libs/boost:=[zlib] >=dev-libs/libmcfp-1.2.2 >=sci-libs/libcifpp-5.1.0
 SLOT=0
 SRC_URI=https://github.com/PDB-REDO/dssp/archive/refs/tags/v4.4.1.tar.gz -> dssp-4.4.1.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=013118d1b74efdd7338221c53cb9cfd2
diff --git a/metadata/md5-cache/sci-chemistry/dssp-4.4.4.1 b/metadata/md5-cache/sci-chemistry/dssp-4.4.4.1
index 22fd53dd4463..82106e8f1203 100644
--- a/metadata/md5-cache/sci-chemistry/dssp-4.4.4.1
+++ b/metadata/md5-cache/sci-chemistry/dssp-4.4.4.1
@@ -1,4 +1,4 @@
-BDEPEND=dev-libs/boost:=[zlib] >=dev-libs/libmcfp-1.2.2 >=sci-libs/libcifpp-5.2.0 >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=dev-libs/boost:=[zlib] >=dev-libs/libmcfp-1.2.2 >=sci-libs/libcifpp-5.2.0 app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare test
 DESCRIPTION=The protein secondary structure standard
 EAPI=8
@@ -9,5 +9,5 @@ LICENSE=BSD-2
 RDEPEND=dev-libs/boost:=[zlib] >=dev-libs/libmcfp-1.2.2 >=sci-libs/libcifpp-5.2.0
 SLOT=0
 SRC_URI=https://github.com/PDB-REDO/dssp/archive/refs/tags/v4.4.4.1.tar.gz -> dssp-4.4.4.1.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=63e550aeee23032d4bfbef6cd6181249
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2018.8-r2 b/metadata/md5-cache/sci-chemistry/gromacs-2018.8-r2
index 35089ab9f1b1..9764c438bfd2 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2018.8-r2
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2018.8-r2
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( <sys-apps/hwloc-2:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( <sys-apps/hwloc-2:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) virtual/pkgconfig app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) cuda? ( single-precision )
 RESTRICT=!test? ( test )
 SLOT=0/2018.8
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2018.8.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2018.8.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2018.8.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=62115051b6cff243b77f66789752bd3f
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2019.6-r3 b/metadata/md5-cache/sci-chemistry/gromacs-2019.6-r3
index 828a6db1b2b1..d4031c2a359c 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2019.6-r3
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2019.6-r3
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14:= ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14:= ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) virtual/pkgconfig app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) cuda? ( single-precision )
 RESTRICT=!test? ( test )
 SLOT=0/2019.6
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2019.6.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2019.6.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2019.6.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=9831218533783189ee2ad99f964b56b4
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2020.7-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2020.7-r1
index d13510387bcf..af96cbd04d57 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2020.7-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2020.7-r1
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14:= ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14:= ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cud
 RESTRICT=!test? ( test )
 SLOT=0/2020.7
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2020.7.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2020.7.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2020.7.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=d40495ba7090c595e2059b309a877501
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.6 b/metadata/md5-cache/sci-chemistry/gromacs-2021.6
index 5efe61c0a60b..2062702fd77b 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.6
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.6
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cud
 RESTRICT=!test? ( test )
 SLOT=0/2021.6
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2021.6.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2021.6.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2021.6.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=a1d35cded4ab63268211d99223aeacf7
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.7-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2021.7-r1
index b0182efcf1ac..35054af1e0da 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.7-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.7-r1
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cud
 RESTRICT=!test? ( test )
 SLOT=0/2021.7
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2021.7.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2021.7.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2021.7.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=4b0aa41558808feac8fca5b8a7590b92
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.5-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2022.5-r1
index 607922cc4930..b204a1e0f760 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.5-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2022.5-r1
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cud
 RESTRICT=!test? ( test )
 SLOT=0/2022.5
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2022.5.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2022.5.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2022.5.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=9c1c98b85f9cd9f4cb653f294a9724b8
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.6 b/metadata/md5-cache/sci-chemistry/gromacs-2022.6
index 6eb42da5e0fe..277495b1bdd1 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.6
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2022.6
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cud
 RESTRICT=!test? ( test )
 SLOT=0/2022.6
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2022.6.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2022.6.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2022.6.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=9c1c98b85f9cd9f4cb653f294a9724b8
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.9999 b/metadata/md5-cache/sci-chemistry/gromacs-2022.9999
index 34174779d613..93b6e06e5745 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2022.9999
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -11,5 +11,5 @@ RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profi
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) opencl? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_10 python_single_target_python3_11 python_single_target_python3_12 )
 RESTRICT=!test? ( test )
 SLOT=0/2022.9999
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=9c1c98b85f9cd9f4cb653f294a9724b8
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2023.1-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2023.1-r1
index 0a1b9d13f9cd..ee7e0c177cc1 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2023.1-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2023.1-r1
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cud
 RESTRICT=!test? ( test )
 SLOT=0/2023.1
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2023.1.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2023.1.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2023.1.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=691421bc1297877922d055d24f7e7e34
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2023.2 b/metadata/md5-cache/sci-chemistry/gromacs-2023.2
index 62c6b2f2701f..43b8d89f1077 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2023.2
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2023.2
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cud
 RESTRICT=!test? ( test )
 SLOT=0/2023.2
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2023.2.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2023.2.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2023.2.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=691421bc1297877922d055d24f7e7e34
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2023.9999 b/metadata/md5-cache/sci-chemistry/gromacs-2023.9999
index 98c4eb6af0f3..8b33d3d3453e 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2023.9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2023.9999
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -11,5 +11,5 @@ RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profi
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) opencl? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_10 python_single_target_python3_11 python_single_target_python3_12 )
 RESTRICT=!test? ( test )
 SLOT=0/2023.9999
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=691421bc1297877922d055d24f7e7e34
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2024.9999 b/metadata/md5-cache/sci-chemistry/gromacs-2024.9999
index 61ed298ab544..36c3700f5c95 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2024.9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2024.9999
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -11,5 +11,5 @@ RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profi
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) opencl? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_10 python_single_target_python3_11 python_single_target_python3_12 )
 RESTRICT=!test? ( test )
 SLOT=0/2024.9999
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=691421bc1297877922d055d24f7e7e34
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2024_beta b/metadata/md5-cache/sci-chemistry/gromacs-2024_beta
index e7593bc893ae..4c6170dcb5a4 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2024_beta
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2024_beta
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cud
 RESTRICT=!test? ( test )
 SLOT=0/2024_beta
 SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2024-beta.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2024-beta.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2024-beta.tar.gz )
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=691421bc1297877922d055d24f7e7e34
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-9999 b/metadata/md5-cache/sci-chemistry/gromacs-9999
index 4b139833050f..c24ef6e80c35 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-9999
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) python_single_target_python3_12? ( dev-lang/python:3.12 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] dev-python/sphinx-copybutton[python_targets_python3_10(-)] dev-python/sphinx-inline-tabs[python_targets_python3_10(-)] dev-python/sphinx-argparse[python_targets_python3_10(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] dev-python/sphinx-copybutton[python_targets_python3_11(-)] dev-python/sphinx-inline-tabs[python_targets_python3_11(-)] dev-python/sphinx-argparse[python_targets_python3_11(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_11(-)] ) python_single_target_python3_12? ( dev-python/sphinx[python_targets_python3_12(-)] dev-python/sphinx-copybutton[python_targets_python3_12(-)] dev-python/sphinx-inline-tabs[python_targets_python3_12(-)] dev-python/sphinx-argparse[python_targets_python3_12(-)] dev-python/sphinxcontrib-autoprogram[python_targets_python3_12(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) app-alternatives/ninja >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -11,5 +11,5 @@ RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11:=[profi
 REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) opencl? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_10 python_single_target_python3_11 python_single_target_python3_12 )
 RESTRICT=!test? ( test )
 SLOT=0/9999
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	cuda	283d0f298f6c196c755a0f8d50daca85	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	readme.gentoo-r1	204091a2cde6179cd9d3db26d09412d3	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=691421bc1297877922d055d24f7e7e34
diff --git a/metadata/md5-cache/sci-chemistry/mdtraj-1.9.7 b/metadata/md5-cache/sci-chemistry/mdtraj-1.9.7
index 68c2da9a7bbc..6b675797060f 100644
--- a/metadata/md5-cache/sci-chemistry/mdtraj-1.9.7
+++ b/metadata/md5-cache/sci-chemistry/mdtraj-1.9.7
@@ -13,5 +13,5 @@ REQUIRED_USE=|| ( python_targets_python3_10 python_targets_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://files.pythonhosted.org/packages/source/m/mdtraj/mdtraj-1.9.7.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	pypi	2eecb475512bc76e5ea9192a681b9e6b	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	pypi	2eecb475512bc76e5ea9192a681b9e6b	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
 _md5_=8c77a7caf33c1c0bf0b66574f9082858
diff --git a/metadata/md5-cache/sci-chemistry/modeller-9.25 b/metadata/md5-cache/sci-chemistry/modeller-9.25
index e3f578df5017..0a89ffecb365 100644
--- a/metadata/md5-cache/sci-chemistry/modeller-9.25
+++ b/metadata/md5-cache/sci-chemistry/modeller-9.25
@@ -13,5 +13,5 @@ REQUIRED_USE=|| ( python_targets_python3_10 )
 RESTRICT=mirror
 SLOT=0
 SRC_URI=https://salilab.org/modeller/9.25/modeller-9.25.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
 _md5_=1c68117b2425090a258fc04144469ec6
diff --git a/metadata/md5-cache/sci-chemistry/molequeue-0.9.0-r1 b/metadata/md5-cache/sci-chemistry/molequeue-0.9.0-r1
index c550785c5db1..1490a74d6fed 100644
--- a/metadata/md5-cache/sci-chemistry/molequeue-0.9.0-r1
+++ b/metadata/md5-cache/sci-chemistry/molequeue-0.9.0-r1
@@ -1,4 +1,4 @@
-BDEPEND=doc? ( app-doc/doxygen ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 test? ( x11-base/xorg-server[xvfb] x11-apps/xhost )
+BDEPEND=doc? ( app-doc/doxygen ) app-alternatives/ninja >=dev-util/cmake-3.20.5 test? ( x11-base/xorg-server[xvfb] x11-apps/xhost )
 DEFINED_PHASES=compile configure install prepare test
 DEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtwidgets:5 zeromq? ( python_targets_python3_10? ( dev-lang/python:3.10 ) python_targets_python3_11? ( dev-lang/python:3.11 ) net-libs/cppzmq:0= )
 DESCRIPTION=Abstract, manage and coordinate execution of tasks
@@ -13,5 +13,5 @@ REQUIRED_USE=server? ( client ) test? ( server ) zeromq? ( || ( python_targets_p
 RESTRICT=test !test? ( test )
 SLOT=0
 SRC_URI=https://github.com/OpenChemistry/molequeue/archive/0.9.0.tar.gz -> molequeue-0.9.0.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	virtualx	817571665ee28575da44ee08135089e5	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	virtualx	817571665ee28575da44ee08135089e5	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=1315f8fda2c7190895e00c847be437be
diff --git a/metadata/md5-cache/sci-chemistry/molsketch-0.7.2-r1 b/metadata/md5-cache/sci-chemistry/molsketch-0.7.2-r1
index 8589c25cbb80..23a0ee6dc175 100644
--- a/metadata/md5-cache/sci-chemistry/molsketch-0.7.2-r1
+++ b/metadata/md5-cache/sci-chemistry/molsketch-0.7.2-r1
@@ -1,4 +1,4 @@
-BDEPEND=dev-qt/linguist-tools:5 >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=dev-qt/linguist-tools:5 app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst postrm preinst prepare test
 DEPEND=>=sci-chemistry/openbabel-3:= dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtprintsupport:5 dev-qt/qtsvg:5 dev-qt/qtwidgets:5
 DESCRIPTION=A drawing tool for 2D molecular structures
@@ -11,5 +11,5 @@ LICENSE=GPL-2
 RDEPEND=>=sci-chemistry/openbabel-3:= dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtprintsupport:5 dev-qt/qtsvg:5 dev-qt/qtwidgets:5
 SLOT=0
 SRC_URI=mirror://sourceforge/project/molsketch/Molsketch/Molsketch-0.7.2-src.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=bfb3b4e082b1e506b991cf3510a50f16
diff --git a/metadata/md5-cache/sci-chemistry/nmrglue-0.9 b/metadata/md5-cache/sci-chemistry/nmrglue-0.9
index 8d325b20f541..4decbf216b06 100644
--- a/metadata/md5-cache/sci-chemistry/nmrglue-0.9
+++ b/metadata/md5-cache/sci-chemistry/nmrglue-0.9
@@ -13,5 +13,5 @@ REQUIRED_USE=|| ( python_targets_python3_10 python_targets_python3_11 )
 RESTRICT=test !test? ( test )
 SLOT=0
 SRC_URI=https://github.com/jjhelmus/nmrglue/archive/v0.9.tar.gz -> nmrglue-0.9.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
 _md5_=35402f3cad87acaf5206a404dff8d4ae
diff --git a/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225 b/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225
index 34dd150bc1c1..f97e43854cef 100644
--- a/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225
+++ b/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225
@@ -1,4 +1,4 @@
-BDEPEND=dev-lang/perl doc? ( app-doc/doxygen dev-texlive/texlive-latex ) perl? ( >=dev-lang/swig-2 ) python? ( >=dev-lang/swig-2 ) test? ( dev-lang/python ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=dev-lang/perl doc? ( app-doc/doxygen dev-texlive/texlive-latex ) perl? ( >=dev-lang/swig-2 ) python? ( >=dev-lang/swig-2 ) test? ( dev-lang/python ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst postrm prepare pretend setup test
 DEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_10? ( dev-lang/python:3.10 ) python_targets_python3_11? ( dev-lang/python:3.11 ) ) wxwidgets? ( x11-libs/wxGTK:3.0-gtk3[X] ) perl? ( dev-lang/perl )
 DESCRIPTION=Interconverts file formats used in molecular modeling
@@ -13,5 +13,5 @@ REQUIRED_USE=python? ( || ( python_targets_python3_10 python_targets_python3_11
 RESTRICT=!test? ( test )
 SLOT=0/7.0.0
 SRC_URI=https://github.com/openbabel/openbabel/archive/08e23f39b0cc39b4eebd937a5a2ffc1a7bac3e1b.tar.gz -> openbabel-3.1.1_p20210225.tar.gz https://openbabel.org/docs/dev/_static/babel130.png -> openbabel.png https://openbabel.org/OBTitle.jpg -> openbabel.jpg
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	wxwidgets	9a707a3f9f1ea7aa703b1e46552291e5	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	wxwidgets	9a707a3f9f1ea7aa703b1e46552291e5	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=41842cb4d1179218c4eab2269054b02f
diff --git a/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225-r1 b/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225-r1
index e22233b0579c..8a3b49748b1e 100644
--- a/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225-r1
+++ b/metadata/md5-cache/sci-chemistry/openbabel-3.1.1_p20210225-r1
@@ -1,4 +1,4 @@
-BDEPEND=dev-lang/perl doc? ( app-doc/doxygen dev-texlive/texlive-latex ) perl? ( >=dev-lang/swig-2 ) python? ( >=dev-lang/swig-2 ) test? ( dev-lang/python ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=dev-lang/perl doc? ( app-doc/doxygen dev-texlive/texlive-latex ) perl? ( >=dev-lang/swig-2 ) python? ( >=dev-lang/swig-2 ) test? ( dev-lang/python ) app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst postrm prepare pretend setup test
 DEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_10? ( dev-lang/python:3.10 ) python_targets_python3_11? ( dev-lang/python:3.11 ) ) wxwidgets? ( x11-libs/wxGTK:3.2-gtk3[X] ) perl? ( dev-lang/perl )
 DESCRIPTION=Interconverts file formats used in molecular modeling
@@ -13,5 +13,5 @@ REQUIRED_USE=python? ( || ( python_targets_python3_10 python_targets_python3_11
 RESTRICT=!test? ( test )
 SLOT=0/7.0.0
 SRC_URI=https://github.com/openbabel/openbabel/archive/08e23f39b0cc39b4eebd937a5a2ffc1a7bac3e1b.tar.gz -> openbabel-3.1.1_p20210225.tar.gz https://openbabel.org/docs/dev/_static/babel130.png -> openbabel.png https://openbabel.org/OBTitle.jpg -> openbabel.jpg
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	wxwidgets	9a707a3f9f1ea7aa703b1e46552291e5	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	wxwidgets	9a707a3f9f1ea7aa703b1e46552291e5	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=9594ff6dc68f04bbd2bda927caa395f8
diff --git a/metadata/md5-cache/sci-chemistry/openbabel-9999 b/metadata/md5-cache/sci-chemistry/openbabel-9999
index 2cb47ca62ff2..46c177742633 100644
--- a/metadata/md5-cache/sci-chemistry/openbabel-9999
+++ b/metadata/md5-cache/sci-chemistry/openbabel-9999
@@ -1,4 +1,4 @@
-BDEPEND=dev-lang/perl doc? ( app-doc/doxygen dev-texlive/texlive-latex ) perl? ( >=dev-lang/swig-2 ) python? ( >=dev-lang/swig-2 ) test? ( dev-lang/python ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=dev-lang/perl doc? ( app-doc/doxygen dev-texlive/texlive-latex ) perl? ( >=dev-lang/swig-2 ) python? ( >=dev-lang/swig-2 ) test? ( dev-lang/python ) app-alternatives/ninja >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst postrm prepare pretend setup test unpack
 DEPEND=dev-cpp/eigen:3 dev-libs/libxml2:2 sys-libs/zlib:= inchi? ( sci-libs/inchi ) json? ( >=dev-libs/rapidjson-1.1.0 ) png? ( x11-libs/cairo ) python? ( python_targets_python3_10? ( dev-lang/python:3.10 ) python_targets_python3_11? ( dev-lang/python:3.11 ) ) wxwidgets? ( x11-libs/wxGTK:3.2-gtk3[X] ) perl? ( dev-lang/perl )
 DESCRIPTION=Interconverts file formats used in molecular modeling
@@ -13,5 +13,5 @@ REQUIRED_USE=python? ( || ( python_targets_python3_10 python_targets_python3_11
 RESTRICT=!test? ( test )
 SLOT=0/7.0.0
 SRC_URI=https://openbabel.org/docs/dev/_static/babel130.png -> openbabel.png https://openbabel.org/OBTitle.jpg -> openbabel.jpg
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	wxwidgets	9a707a3f9f1ea7aa703b1e46552291e5	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	desktop	021728fdc1b03b36357dbc89489e0f0d	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	perl-functions	c3fca037246e877693badea0df3b0ef8	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	wxwidgets	9a707a3f9f1ea7aa703b1e46552291e5	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=cc921fcb387fcad7c0f237cd5dbf4812
diff --git a/metadata/md5-cache/sci-chemistry/pdbcat-1.3-r1 b/metadata/md5-cache/sci-chemistry/pdbcat-1.3-r1
index 52908112c300..f853d0e35454 100644
--- a/metadata/md5-cache/sci-chemistry/pdbcat-1.3-r1
+++ b/metadata/md5-cache/sci-chemistry/pdbcat-1.3-r1
@@ -1,4 +1,4 @@
-BDEPEND=>=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install prepare test
 DESCRIPTION=Manipulate and process PDB files using tools such as Perl, awk, etc
 EAPI=8
@@ -8,5 +8,5 @@ KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=free-noncomm
 SLOT=0
 SRC_URI=http://www.ks.uiuc.edu/Development/MDTools/pdbcat/files/pdbcat-1.3.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=468efdc0276a4b9606711e3ba7fc6d8f
diff --git a/metadata/md5-cache/sci-chemistry/pdbmat-3.89-r1 b/metadata/md5-cache/sci-chemistry/pdbmat-3.89-r1
index ea5cc903ce38..c90fa63dfeee 100644
--- a/metadata/md5-cache/sci-chemistry/pdbmat-3.89-r1
+++ b/metadata/md5-cache/sci-chemistry/pdbmat-3.89-r1
@@ -1,4 +1,4 @@
-BDEPEND=>=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 virtual/fortran
+BDEPEND=app-alternatives/ninja >=dev-util/cmake-3.20.5 virtual/fortran
 DEFINED_PHASES=compile configure install prepare setup test
 DEPEND=virtual/fortran
 DESCRIPTION=Calculate Tirion's model from pdb structures
@@ -11,5 +11,5 @@ LICENSE=CeCILL-2
 RDEPEND=virtual/fortran
 SLOT=0
 SRC_URI=http://ecole.modelisation.free.fr/enm2011.tar.gz -> pdbmat-3.89.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	fortran-2	40c4450f1c4ecb2ee694d96e1958d4ea	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	fortran-2	40c4450f1c4ecb2ee694d96e1958d4ea	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=d9c289801412f2ea4102c59abe9d1df7
diff --git a/metadata/md5-cache/sci-chemistry/propka-3.4.0 b/metadata/md5-cache/sci-chemistry/propka-3.4.0
index 307335ce7c04..be1b554910b0 100644
--- a/metadata/md5-cache/sci-chemistry/propka-3.4.0
+++ b/metadata/md5-cache/sci-chemistry/propka-3.4.0
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( python_targets_python3_10 python_targets_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/jensengroup/propka/archive/refs/tags/v3.4.0.tar.gz -> propka-3.4.0.gh.tar.gz
-_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
+_eclasses_=distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc
 _md5_=df9c2734ddc4d3199b2a42247a6a9496
diff --git a/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r3 b/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r3
index 776a775eb7c6..b160416f596a 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r3
+++ b/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r3
@@ -13,5 +13,5 @@ RDEPEND=dev-cpp/msgpack-cxx dev-libs/mmtf-cpp dev-python/pyopengl[python_targets
 REQUIRED_USE=|| ( python_targets_python3_10 python_targets_python3_11 )
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~pacho/pymol/pymol-1.8.4.0.png.xz https://github.com/schrodinger/pymol-open-source/archive/v2.5.0.tar.gz -> pymol-2.5.0.tar.gz
-_eclasses_=desktop	021728fdc1b03b36357dbc89489e0f0d	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=desktop	021728fdc1b03b36357dbc89489e0f0d	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=f210230d3c07b2116be882b67561c483
diff --git a/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r4 b/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r4
index 9ef939efc87b..3e80b42870c2 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r4
+++ b/metadata/md5-cache/sci-chemistry/pymol-2.5.0-r4
@@ -13,5 +13,5 @@ RDEPEND=dev-cpp/msgpack-cxx dev-libs/mmtf-cpp dev-python/pyopengl[python_targets
 REQUIRED_USE=|| ( python_targets_python3_10 python_targets_python3_11 )
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~pacho/pymol/pymol-1.8.4.0.png.xz https://github.com/schrodinger/pymol-open-source/archive/v2.5.0.tar.gz -> pymol-2.5.0.tar.gz
-_eclasses_=desktop	021728fdc1b03b36357dbc89489e0f0d	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=desktop	021728fdc1b03b36357dbc89489e0f0d	distutils-r1	2329ddf7eec9f8177aec51648249d790	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multibuild	d67e78a235f541871c7dfe4cf7931489	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	8a28fa6d3e3bc96ff8a7eff2badbe71f	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg	4a14c5c24f121e7da66e5aab4a168c6e	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=16905c83a0ecc4cab75abb99c0910ff0
diff --git a/metadata/md5-cache/sci-chemistry/tm-align-20150914-r1 b/metadata/md5-cache/sci-chemistry/tm-align-20150914-r1
index 6173eeacd395..7976c6cb9cc6 100644
--- a/metadata/md5-cache/sci-chemistry/tm-align-20150914-r1
+++ b/metadata/md5-cache/sci-chemistry/tm-align-20150914-r1
@@ -1,4 +1,4 @@
-BDEPEND=>=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 virtual/fortran
+BDEPEND=app-alternatives/ninja >=dev-util/cmake-3.20.5 virtual/fortran
 DEFINED_PHASES=compile configure install prepare setup test
 DEPEND=virtual/fortran
 DESCRIPTION=Quick & Accurate Structural Alignment
@@ -11,5 +11,5 @@ LICENSE=tm-align
 RDEPEND=virtual/fortran
 SLOT=0
 SRC_URI=http://zhanglab.ccmb.med.umich.edu/TM-align/TMtools20150914.tar.gz
-_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	fortran-2	40c4450f1c4ecb2ee694d96e1958d4ea	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=cmake	0f2e0c197fad0312f3c4765c9cf36271	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	fortran-2	40c4450f1c4ecb2ee694d96e1958d4ea	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=cfa1e63224fea8203e5337a0c285b503
diff --git a/metadata/md5-cache/sci-chemistry/votca-2022 b/metadata/md5-cache/sci-chemistry/votca-2022
index 194561dda603..4422f2ebc6e1 100644
--- a/metadata/md5-cache/sci-chemistry/votca-2022
+++ b/metadata/md5-cache/sci-chemistry/votca-2022
@@ -1,4 +1,4 @@
-BDEPEND=virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=virtual/pkgconfig app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare setup test
 DEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_10? ( dev-lang/python:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
 DESCRIPTION=Versatile Object-oriented Toolkit for Coarse-graining Applications
@@ -13,5 +13,5 @@ REQUIRED_USE=^^ ( python_single_target_python3_10 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/votca/votca/archive/v2022.tar.gz -> votca-2022.tar.gz
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=90500ca97973846d4fd670f0c29932ac
diff --git a/metadata/md5-cache/sci-chemistry/votca-2022.1 b/metadata/md5-cache/sci-chemistry/votca-2022.1
index 6aded9ae0c20..c9ab94b73fde 100644
--- a/metadata/md5-cache/sci-chemistry/votca-2022.1
+++ b/metadata/md5-cache/sci-chemistry/votca-2022.1
@@ -1,4 +1,4 @@
-BDEPEND=virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+BDEPEND=virtual/pkgconfig app-alternatives/ninja >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare setup test
 DEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_10? ( dev-lang/python:3.10 ) python_single_target_python3_11? ( dev-lang/python:3.11 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
 DESCRIPTION=Versatile Object-oriented Toolkit for Coarse-graining Applications
@@ -13,5 +13,5 @@ REQUIRED_USE=^^ ( python_single_target_python3_10 python_single_target_python3_1
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/votca/votca/archive/v2022.1.tar.gz -> votca-2022.1.tar.gz
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=f241004ff74b0729ca815c59c824e20a
diff --git a/metadata/md5-cache/sci-chemistry/votca-9999 b/metadata/md5-cache/sci-chemistry/votca-9999
index 11726c5cbb12..68404e4d0ab7 100644
--- a/metadata/md5-cache/sci-chemistry/votca-9999
+++ b/metadata/md5-cache/sci-chemistry/votca-9999
@@ -1,4 +1,4 @@
-BDEPEND=virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=virtual/pkgconfig app-alternatives/ninja >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare setup test unpack
 DEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp python_single_target_python3_10? ( dev-lang/python:3.10 ) app-shells/bash:* >=dev-cpp/eigen-3.3 dev-libs/boost:= dev-libs/expat sci-libs/fftw:3.0= dev-lang/perl gromacs? ( sci-chemistry/gromacs:=[gmxapi-legacy(+)] ) sci-libs/hdf5[cxx] sci-libs/libxc sci-libs/libint:2
 DESCRIPTION=Versatile Object-oriented Toolkit for Coarse-graining Applications
@@ -12,5 +12,5 @@ RDEPEND=!sci-libs/votca-tools !sci-chemistry/votca-csg !sci-chemistry/votca-xtp
 REQUIRED_USE=^^ ( python_single_target_python3_10 )
 RESTRICT=!test? ( test )
 SLOT=0
-_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	39e7a84b06eff4efd9f2e0c3d1668b98	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
+_eclasses_=bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	cmake	0f2e0c197fad0312f3c4765c9cf36271	eapi8-dosym	5ac4857ad078256d939c44f7c64197a9	flag-o-matic	c816c598969cbaf38cc02d2496ad2e98	git-r3	5133e393e8717a3a093660f990801dc1	multilib	c19072c3cd7ac5cb21de013f7e9832e0	multiprocessing	30ead54fa2e2b5f9cd4e612ffc34d0fe	ninja-utils	c8951c1dfcc1d43e3f967f61fd0ec59c	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	474cb53a7d1b62721a91809a1d702661	toolchain-funcs	eed10cf5e5a06916e654d31f5a1925cc	xdg-utils	baea6080dd821f5562d715887954c9d3
 _md5_=4652fac7d0d919a31b5394224c0f9960