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diff --git a/metadata/md5-cache/sci-chemistry/Manifest.gz b/metadata/md5-cache/sci-chemistry/Manifest.gz
index b8da20a6bac2..426c17d2375e 100644
--- a/metadata/md5-cache/sci-chemistry/Manifest.gz
+++ b/metadata/md5-cache/sci-chemistry/Manifest.gz
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2019.6-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2019.6-r1
deleted file mode 100644
index 9f8f20c8e024..000000000000
--- a/metadata/md5-cache/sci-chemistry/gromacs-2019.6-r1
+++ /dev/null
@@ -1,16 +0,0 @@
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deleted file mode 100644
index 3162280bbff6..000000000000
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diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1
deleted file mode 100644
index 0ccc5e0f6d9e..000000000000
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1
+++ /dev/null
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diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.5 b/metadata/md5-cache/sci-chemistry/gromacs-2021.5
deleted file mode 100644
index dc19b9729738..000000000000
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.5
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diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.3 b/metadata/md5-cache/sci-chemistry/gromacs-2022.3
deleted file mode 100644
index 244989cfc293..000000000000
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.3
+++ /dev/null
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-SLOT=0/2022.3
-SRC_URI=https://ftp.gromacs.org/gromacs/gromacs-2022.3.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2022.3.pdf ) test? ( https://ftp.gromacs.org/regressiontests/regressiontests-2022.3.tar.gz )
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-_md5_=cdd826a94c74837171c33e5212e21e04