gentoo resync : 14.05.2020

27 files changed, 58 insertions, 58 deletions

diff --git a/metadata/md5-cache/sci-biology/GBrowse-2.48-r1 b/metadata/md5-cache/sci-biology/GBrowse-2.48-r1
index 50bebb04d140..83927b94931f 100644
--- a/metadata/md5-cache/sci-biology/GBrowse-2.48-r1
+++ b/metadata/md5-cache/sci-biology/GBrowse-2.48-r1
@@ -9,5 +9,5 @@ LICENSE=|| ( Artistic GPL-1+ )
 RDEPEND=!<sci-biology/GBrowse-2.44-r1 >=sci-biology/bioperl-1.6.9 >=dev-perl/Bio-Graphics-2.09 >=dev-perl/GD-2.07 >=dev-perl/CGI-Session-4.02 dev-perl/IO-String dev-perl/JSON dev-perl/libwww-perl dev-perl/Statistics-Descriptive !minimal? ( dev-perl/Bio-Das >=dev-perl/Bio-SamTools-1.20 dev-perl/Crypt-SSLeay dev-perl/DB_File-Lock dev-perl/DBI mysql? ( dev-perl/DBD-mysql ) postgres? ( dev-perl/DBD-Pg ) sqlite? ( dev-perl/DBD-SQLite ) dev-perl/FCGI dev-perl/File-NFSLock dev-perl/GD-SVG dev-perl/Net-OpenID-Consumer dev-perl/Net-SMTP-SSL ) dev-lang/perl:=[-build(-)] >=app-admin/webapp-config-1.50.15
 SLOT=0
 SRC_URI=mirror://cpan/authors/id/L/LD/LDS/GBrowse-2.48.tar.gz
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	3cd8bad0d31e525cd26be1bfa4e61631	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	webapp	16783e418aca3ffa461d68310bf7ab12
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	b5891c9326ad2e7905c011d44c927c34	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	webapp	16783e418aca3ffa461d68310bf7ab12
 _md5_=bccaeef3292f6df307fc14fb5a2a74b2
diff --git a/metadata/md5-cache/sci-biology/HTSeq-0.9.1 b/metadata/md5-cache/sci-biology/HTSeq-0.9.1
index 23e7dd9d312c..fdb81fe2e82e 100644
--- a/metadata/md5-cache/sci-biology/HTSeq-0.9.1
+++ b/metadata/md5-cache/sci-biology/HTSeq-0.9.1
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-biology/pysam[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-lang/swig-3.0.8 dev-python/cython[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-biology/pysam[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-lang/swig-3.0.8 dev-python/cython[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 DESCRIPTION=Python support for SAM/BAM/Bowtie/FASTA/Q/GFF/GTF files
 EAPI=6
 HOMEPAGE=https://htseq.readthedocs.io/
 IUSE=python_targets_python3_6
 KEYWORDS=~amd64
 LICENSE=GPL-3+
-RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-biology/pysam[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-biology/pysam[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 )
 SLOT=0
 SRC_URI=mirror://pypi/H/HTSeq/HTSeq-0.9.1.tar.gz
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	distutils-r1	b33fa13a5178ad9bf895a5190d20cdc7	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	distutils-r1	054fa5f0442c7ccb4d4a05410d92123b	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=1a7e20f6705425c8dc29ce2c240db0b2
diff --git a/metadata/md5-cache/sci-biology/HTSeq-9999 b/metadata/md5-cache/sci-biology/HTSeq-9999
index 466307539a7b..322b382cdc12 100644
--- a/metadata/md5-cache/sci-biology/HTSeq-9999
+++ b/metadata/md5-cache/sci-biology/HTSeq-9999
@@ -1,13 +1,13 @@
 DEFINED_PHASES=compile configure install prepare test unpack
-DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-biology/pysam[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-lang/swig-3.0.8 dev-python/cython[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-vcs/git-1.8.2.1[curl]
+DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-biology/pysam[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-lang/swig-3.0.8 dev-python/cython[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-vcs/git-1.8.2.1[curl]
 DESCRIPTION=Python support for SAM/BAM/Bowtie/FASTA/Q/GFF/GTF files
 EAPI=6
 HOMEPAGE=https://htseq.readthedocs.io/
 IUSE=python_targets_python3_6
 LICENSE=GPL-3+
 PROPERTIES=live
-RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-biology/pysam[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-biology/pysam[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 )
 SLOT=0
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	distutils-r1	b33fa13a5178ad9bf895a5190d20cdc7	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	git-r3	86a0188f2ad9eb3d65e4d031ab8a0422	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	distutils-r1	054fa5f0442c7ccb4d4a05410d92123b	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	git-r3	86a0188f2ad9eb3d65e4d031ab8a0422	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=1a7e20f6705425c8dc29ce2c240db0b2
diff --git a/metadata/md5-cache/sci-biology/Manifest.gz b/metadata/md5-cache/sci-biology/Manifest.gz
index 0049094e3c86..9a85be79869a 100644
--- a/metadata/md5-cache/sci-biology/Manifest.gz
+++ b/metadata/md5-cache/sci-biology/Manifest.gz
diff --git a/metadata/md5-cache/sci-biology/amos-3.1.0-r4 b/metadata/md5-cache/sci-biology/amos-3.1.0-r4
index 50d5e0ea80ac..763ff21f0a72 100644
--- a/metadata/md5-cache/sci-biology/amos-3.1.0-r4
+++ b/metadata/md5-cache/sci-biology/amos-3.1.0-r4
@@ -6,9 +6,9 @@ HOMEPAGE=http://amos.sourceforge.net/
 IUSE=+python_single_target_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=Artistic
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) dev-perl/DBI dev-perl/Statistics-Descriptive sci-biology/mummer
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) dev-perl/DBI dev-perl/Statistics-Descriptive sci-biology/mummer
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=mirror://sourceforge/amos/amos-3.1.0.tar.gz https://dev.gentoo.org/~soap/distfiles/amos-3.1.0-fix-c++14.patch.bz2
-_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=aec6d1c76d5ea621c66e803800e2b3c4
diff --git a/metadata/md5-cache/sci-biology/bcftools-1.5 b/metadata/md5-cache/sci-biology/bcftools-1.5
index 3b01f32f50a5..ae6b7418ffcd 100644
--- a/metadata/md5-cache/sci-biology/bcftools-1.5
+++ b/metadata/md5-cache/sci-biology/bcftools-1.5
@@ -1,14 +1,14 @@
 DEFINED_PHASES=configure prepare
-DEPEND=dev-lang/perl =sci-libs/htslib-1.5*:= sys-libs/zlib python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+DEPEND=dev-lang/perl =sci-libs/htslib-1.5*:= sys-libs/zlib python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DESCRIPTION=Utilities for variant calling and manipulating VCF and BCF files
 EAPI=6
 HOMEPAGE=http://www.htslib.org
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=MIT
-RDEPEND=dev-lang/perl =sci-libs/htslib-1.5*:= sys-libs/zlib python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=dev-lang/perl =sci-libs/htslib-1.5*:= sys-libs/zlib python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=https://github.com/samtools/bcftools/releases/download/1.5/bcftools-1.5.tar.bz2
-_eclasses_=multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=e289371e3fec376baf8fe36c652ca521
diff --git a/metadata/md5-cache/sci-biology/bcftools-1.9-r2 b/metadata/md5-cache/sci-biology/bcftools-1.9-r2
index 3781a805d051..495922c6122c 100644
--- a/metadata/md5-cache/sci-biology/bcftools-1.9-r2
+++ b/metadata/md5-cache/sci-biology/bcftools-1.9-r2
@@ -1,14 +1,14 @@
 DEFINED_PHASES=configure prepare setup
-DEPEND=dev-lang/perl python_single_target_python3_6? ( dev-python/matplotlib[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/matplotlib[python_targets_python3_7(-)] ) =sci-libs/htslib-1.9*:= sys-libs/zlib:= python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.7-r1:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
+DEPEND=dev-lang/perl python_single_target_python3_6? ( dev-python/matplotlib[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/matplotlib[python_targets_python3_7(-)] ) =sci-libs/htslib-1.9*:= sys-libs/zlib:= python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
 DESCRIPTION=Utilities for variant calling and manipulating VCF and BCF files
 EAPI=7
 HOMEPAGE=http://www.htslib.org
 IUSE=python_single_target_python3_6 python_single_target_python3_7
 KEYWORDS=~amd64 ~x86
 LICENSE=MIT
-RDEPEND=dev-lang/perl python_single_target_python3_6? ( dev-python/matplotlib[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/matplotlib[python_targets_python3_7(-)] ) =sci-libs/htslib-1.9*:= sys-libs/zlib:= python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.7-r1:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
+RDEPEND=dev-lang/perl python_single_target_python3_6? ( dev-python/matplotlib[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/matplotlib[python_targets_python3_7(-)] ) =sci-libs/htslib-1.9*:= sys-libs/zlib:= python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
 REQUIRED_USE=^^ ( python_single_target_python3_6 python_single_target_python3_7 )
 SLOT=0
 SRC_URI=https://github.com/samtools/bcftools/releases/download/1.9/bcftools-1.9.tar.bz2
-_eclasses_=multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=3bd4e9294012ee3e5fdd9e07796a4cc2
diff --git a/metadata/md5-cache/sci-biology/bedtools-2.26.0 b/metadata/md5-cache/sci-biology/bedtools-2.26.0
index 7a9ec6f06cb0..7abd3bc531b7 100644
--- a/metadata/md5-cache/sci-biology/bedtools-2.26.0
+++ b/metadata/md5-cache/sci-biology/bedtools-2.26.0
@@ -1,5 +1,5 @@
 DEFINED_PHASES=configure install setup
-DEPEND=|| ( >=dev-lang/python-3.6.10:3.6 ) test? ( sci-libs/htslib sci-biology/samtools:0 )
+DEPEND=|| ( dev-lang/python:3.6 ) test? ( sci-libs/htslib sci-biology/samtools:0 )
 DESCRIPTION=Tools for manipulation and analysis of BED, GFF/GTF, VCF, SAM/BAM file formats
 EAPI=6
 HOMEPAGE=https://bedtools.readthedocs.io/
@@ -10,5 +10,5 @@ RDEPEND=sys-libs/zlib
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/arq5x/bedtools2/releases/download/v2.26.0/bedtools-2.26.0.tar.gz https://dev.gentoo.org/~mgorny/dist/bedtools-2.26.0-fix-buildsystem.patch.bz2
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=1b65bed58bf80baf59cb7772dbdb6023
diff --git a/metadata/md5-cache/sci-biology/biopandas-0.2.1 b/metadata/md5-cache/sci-biology/biopandas-0.2.1
index eb597ab3d753..d3e93c36c1fc 100644
--- a/metadata/md5-cache/sci-biology/biopandas-0.2.1
+++ b/metadata/md5-cache/sci-biology/biopandas-0.2.1
@@ -1,15 +1,15 @@
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pandas[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/setuptools[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] test? ( dev-python/nose[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] ) python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pandas[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/setuptools[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] test? ( dev-python/nose[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] ) python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 DESCRIPTION=Molecular Structures in Pandas DataFrames
 EAPI=6
 HOMEPAGE=https://rasbt.github.io/biopandas/ https://github.com/rasbt/biopandas https://pypi.org/project/BioPandas/
 IUSE=test python_targets_python3_6
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=BSD
-RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pandas[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pandas[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=mirror://pypi/B/BioPandas/biopandas-0.2.1.tar.gz
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	distutils-r1	b33fa13a5178ad9bf895a5190d20cdc7	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	distutils-r1	054fa5f0442c7ccb4d4a05410d92123b	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=9aa50282a8f020366a788665165393c5
diff --git a/metadata/md5-cache/sci-biology/bioperl-1.6.9 b/metadata/md5-cache/sci-biology/bioperl-1.6.9
index 975bdfb4666b..1e6e2aa47dc2 100644
--- a/metadata/md5-cache/sci-biology/bioperl-1.6.9
+++ b/metadata/md5-cache/sci-biology/bioperl-1.6.9
@@ -11,5 +11,5 @@ RDEPEND=dev-perl/libwww-perl !minimal? ( dev-perl/Algorithm-Munkres dev-perl/Arr
 REQUIRED_USE=minimal? ( !graphviz )
 SLOT=0
 SRC_URI=mirror://cpan/authors/id/C/CJ/CJFIELDS/BioPerl-1.6.901.tar.gz
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	3cd8bad0d31e525cd26be1bfa4e61631	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	b5891c9326ad2e7905c011d44c927c34	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=be22a76392a6e5c121e4b6d388045faa
diff --git a/metadata/md5-cache/sci-biology/bioperl-db-1.6.9 b/metadata/md5-cache/sci-biology/bioperl-db-1.6.9
index 4f2cfdebaeac..67ef6be0812c 100644
--- a/metadata/md5-cache/sci-biology/bioperl-db-1.6.9
+++ b/metadata/md5-cache/sci-biology/bioperl-db-1.6.9
@@ -10,5 +10,5 @@ RDEPEND=>=sci-biology/bioperl-1.6.9 dev-perl/DBD-mysql dev-perl/DBI sci-biology/
 RESTRICT=test
 SLOT=0
 SRC_URI=mirror://cpan/authors/id/C/CJ/CJFIELDS/BioPerl-DB-1.006900.tar.gz
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	3cd8bad0d31e525cd26be1bfa4e61631	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	b5891c9326ad2e7905c011d44c927c34	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=2470d7ecf1b6ff1902a8d74057748480
diff --git a/metadata/md5-cache/sci-biology/bioperl-network-1.6.9 b/metadata/md5-cache/sci-biology/bioperl-network-1.6.9
index d8a74821e4bf..9b8d483dda6d 100644
--- a/metadata/md5-cache/sci-biology/bioperl-network-1.6.9
+++ b/metadata/md5-cache/sci-biology/bioperl-network-1.6.9
@@ -10,5 +10,5 @@ RDEPEND=>=sci-biology/bioperl-1.6.9 >=dev-perl/Graph-0.86 dev-lang/perl:=[-build
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=mirror://cpan/authors/id/C/CJ/CJFIELDS/BioPerl-Network-1.006900.tar.gz
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	3cd8bad0d31e525cd26be1bfa4e61631	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	b5891c9326ad2e7905c011d44c927c34	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=8f7c4053ffbec76cfad29cca2d99847b
diff --git a/metadata/md5-cache/sci-biology/bioperl-run-1.6.9 b/metadata/md5-cache/sci-biology/bioperl-run-1.6.9
index 540c5422e6e3..fac196a49d16 100644
--- a/metadata/md5-cache/sci-biology/bioperl-run-1.6.9
+++ b/metadata/md5-cache/sci-biology/bioperl-run-1.6.9
@@ -10,5 +10,5 @@ RDEPEND=>=sci-biology/bioperl-1.6.9 !minimal? ( dev-perl/Algorithm-Diff dev-perl
 RESTRICT=test
 SLOT=0
 SRC_URI=mirror://cpan/authors/id/C/CJ/CJFIELDS/BioPerl-Run-1.006900.tar.gz
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	3cd8bad0d31e525cd26be1bfa4e61631	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	b5891c9326ad2e7905c011d44c927c34	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=9caec4e5b47cbf306a1689903f2a018a
diff --git a/metadata/md5-cache/sci-biology/biopython-1.73 b/metadata/md5-cache/sci-biology/biopython-1.73
index 95209b4254ec..01044c846a74 100644
--- a/metadata/md5-cache/sci-biology/biopython-1.73
+++ b/metadata/md5-cache/sci-biology/biopython-1.73
@@ -1,4 +1,4 @@
-BDEPEND=python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.7-r1:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
+BDEPEND=python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
 DEFINED_PHASES=compile configure install postinst prepare test
 DEPEND=dev-python/matplotlib[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/networkx[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/rdflib[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/pygraphviz[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/reportlab-3.5.13-r1[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/pydot[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/setuptools[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sys-devel/flex
 DESCRIPTION=Python modules for computational molecular biology
@@ -7,9 +7,9 @@ HOMEPAGE=https://www.biopython.org/ https://pypi.org/project/biopython/
 IUSE=python_targets_python3_6 python_targets_python3_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=HPND
-RDEPEND=dev-python/matplotlib[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/networkx[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/rdflib[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/pygraphviz[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/reportlab-3.5.13-r1[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/pydot[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.7-r1:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
+RDEPEND=dev-python/matplotlib[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/networkx[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/rdflib[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/pygraphviz[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/reportlab-3.5.13-r1[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/pydot[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 python_targets_python3_7 )
 SLOT=0
 SRC_URI=mirror://pypi/b/biopython/biopython-1.73.tar.gz
-_eclasses_=distutils-r1	b33fa13a5178ad9bf895a5190d20cdc7	eutils	fcb2aa98e1948b835b5ae66ca52868c5	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=distutils-r1	054fa5f0442c7ccb4d4a05410d92123b	eutils	fcb2aa98e1948b835b5ae66ca52868c5	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=a7d43dcf81616b69a0167851abcbe227
diff --git a/metadata/md5-cache/sci-biology/diya-1.0_rc4 b/metadata/md5-cache/sci-biology/diya-1.0_rc4
index 9868f3f7a6cd..0cf1b382bece 100644
--- a/metadata/md5-cache/sci-biology/diya-1.0_rc4
+++ b/metadata/md5-cache/sci-biology/diya-1.0_rc4
@@ -9,5 +9,5 @@ LICENSE=GPL-3
 RDEPEND=sci-biology/bioperl dev-perl/Data-Utilities dev-perl/XML-Simple !minimal? ( sci-biology/mummer sci-biology/glimmer sci-biology/trnascan-se sci-biology/infernal ) dev-lang/perl:=[-build(-)]
 SLOT=0
 SRC_URI=mirror://sourceforge/diyg/files/diya/diya-1.0/diya-1.0-rc4.tar.gz
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	3cd8bad0d31e525cd26be1bfa4e61631	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	perl-module	97206c028d9bdc9f248e022ac5c9fc83	preserve-libs	ef207dc62baddfddfd39a164d9797648	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	unpacker	b5891c9326ad2e7905c011d44c927c34	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=5d4639d7c08c43e2c2208492508fd56c
diff --git a/metadata/md5-cache/sci-biology/last-299-r1 b/metadata/md5-cache/sci-biology/last-299-r1
index 7fb01355a8c9..dec8a1e04ee6 100644
--- a/metadata/md5-cache/sci-biology/last-299-r1
+++ b/metadata/md5-cache/sci-biology/last-299-r1
@@ -6,9 +6,9 @@ HOMEPAGE=http://last.cbrc.jp/
 IUSE=+python_single_target_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-3
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=http://last.cbrc.jp/last-299.zip
-_eclasses_=multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=ec5206661373a6ef6ad77450dfbdb915
diff --git a/metadata/md5-cache/sci-biology/meme-4.11.2_p2 b/metadata/md5-cache/sci-biology/meme-4.11.2_p2
index c5091a550f90..1e9269c95569 100644
--- a/metadata/md5-cache/sci-biology/meme-4.11.2_p2
+++ b/metadata/md5-cache/sci-biology/meme-4.11.2_p2
@@ -1,14 +1,14 @@
 DEFINED_PHASES=configure install prepare setup test
-DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) app-shells/tcsh dev-libs/libxml2:2 dev-libs/libxslt sys-libs/zlib app-text/ghostscript-gpl media-gfx/imagemagick dev-lang/perl:= dev-perl/HTML-Parser dev-perl/HTML-Template dev-perl/Log-Log4perl dev-perl/Math-CDF dev-perl/XML-Compile-SOAP dev-perl/XML-Compile-WSDL11 dev-perl/XML-Parser dev-perl/XML-Simple virtual/perl-Data-Dumper virtual/perl-Exporter virtual/perl-File-Path virtual/perl-File-Spec virtual/perl-File-Temp virtual/perl-Getopt-Long virtual/perl-Scalar-List-Utils virtual/perl-Time-HiRes mpi? ( virtual/mpi ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
+DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) app-shells/tcsh dev-libs/libxml2:2 dev-libs/libxslt sys-libs/zlib app-text/ghostscript-gpl media-gfx/imagemagick dev-lang/perl:= dev-perl/HTML-Parser dev-perl/HTML-Template dev-perl/Log-Log4perl dev-perl/Math-CDF dev-perl/XML-Compile-SOAP dev-perl/XML-Compile-WSDL11 dev-perl/XML-Parser dev-perl/XML-Simple virtual/perl-Data-Dumper virtual/perl-Exporter virtual/perl-File-Path virtual/perl-File-Spec virtual/perl-File-Temp virtual/perl-Getopt-Long virtual/perl-Scalar-List-Utils virtual/perl-Time-HiRes mpi? ( virtual/mpi ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
 DESCRIPTION=The MEME/MAST system - Motif discovery and search
 EAPI=6
 HOMEPAGE=http://meme-suite.org/tools/meme
 IUSE=debug doc examples mpi +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=meme
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) app-shells/tcsh dev-libs/libxml2:2 dev-libs/libxslt sys-libs/zlib app-text/ghostscript-gpl media-gfx/imagemagick dev-lang/perl:= dev-perl/HTML-Parser dev-perl/HTML-Template dev-perl/Log-Log4perl dev-perl/Math-CDF dev-perl/XML-Compile-SOAP dev-perl/XML-Compile-WSDL11 dev-perl/XML-Parser dev-perl/XML-Simple virtual/perl-Data-Dumper virtual/perl-Exporter virtual/perl-File-Path virtual/perl-File-Spec virtual/perl-File-Temp virtual/perl-Getopt-Long virtual/perl-Scalar-List-Utils virtual/perl-Time-HiRes mpi? ( virtual/mpi )
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) app-shells/tcsh dev-libs/libxml2:2 dev-libs/libxslt sys-libs/zlib app-text/ghostscript-gpl media-gfx/imagemagick dev-lang/perl:= dev-perl/HTML-Parser dev-perl/HTML-Template dev-perl/Log-Log4perl dev-perl/Math-CDF dev-perl/XML-Compile-SOAP dev-perl/XML-Compile-WSDL11 dev-perl/XML-Parser dev-perl/XML-Simple virtual/perl-Data-Dumper virtual/perl-Exporter virtual/perl-File-Path virtual/perl-File-Spec virtual/perl-File-Temp virtual/perl-Getopt-Long virtual/perl-Scalar-List-Utils virtual/perl-Time-HiRes mpi? ( virtual/mpi )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=http://meme-suite.org/meme-software/4.11.2/meme_4.11.2.tar.gz
-_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	estack	686eaab303305a908fd57b2fd7617800	libtool	f143db5a74ccd9ca28c1234deffede96	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	versionator	2352c3fc97241f6a02042773c8287748
+_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	estack	686eaab303305a908fd57b2fd7617800	libtool	f143db5a74ccd9ca28c1234deffede96	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	perl-functions	6ec4c4d8fc8324200f1c14e8d158c59b	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	versionator	2352c3fc97241f6a02042773c8287748
 _md5_=a4080439675628436c06de8db9f59c6e
diff --git a/metadata/md5-cache/sci-biology/pysam-0.12.0.1 b/metadata/md5-cache/sci-biology/pysam-0.12.0.1
index 3d6f67e5c369..94bfee027ba2 100644
--- a/metadata/md5-cache/sci-biology/pysam-0.12.0.1
+++ b/metadata/md5-cache/sci-biology/pysam-0.12.0.1
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare test
-DEPEND==sci-libs/htslib-1.5*:= dev-python/cython[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/setuptools[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+DEPEND==sci-libs/htslib-1.5*:= dev-python/cython[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/setuptools[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 DESCRIPTION=Python interface for the SAM/BAM sequence alignment and mapping format
 EAPI=6
 HOMEPAGE=https://github.com/pysam-developers/pysam https://pypi.org/project/pysam/
 IUSE=python_targets_python3_6
 KEYWORDS=~amd64 ~x86
 LICENSE=MIT
-RDEPEND==sci-libs/htslib-1.5*:= python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+RDEPEND==sci-libs/htslib-1.5*:= python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 )
 SLOT=0
 SRC_URI=mirror://pypi/p/pysam/pysam-0.12.0.1.tar.gz
-_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	distutils-r1	b33fa13a5178ad9bf895a5190d20cdc7	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	distutils-r1	054fa5f0442c7ccb4d4a05410d92123b	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=73a20e2f0964572bf64b569361b1235c
diff --git a/metadata/md5-cache/sci-biology/samtools-0.1.20-r3 b/metadata/md5-cache/sci-biology/samtools-0.1.20-r3
index 6475ef7be3e4..c6b9726f2bd8 100644
--- a/metadata/md5-cache/sci-biology/samtools-0.1.20-r3
+++ b/metadata/md5-cache/sci-biology/samtools-0.1.20-r3
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile install postinst prepare setup
-DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) sys-libs/ncurses:0= dev-lang/perl virtual/pkgconfig
+DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) sys-libs/ncurses:0= dev-lang/perl virtual/pkgconfig
 DESCRIPTION=Utilities for analysing and manipulating the SAM/BAM alignment formats
 EAPI=6
 HOMEPAGE=http://samtools.sourceforge.net/
 IUSE=examples +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=MIT
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) sys-libs/ncurses:0= dev-lang/perl
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) sys-libs/ncurses:0= dev-lang/perl
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0.1-legacy
 SRC_URI=https://github.com/samtools/samtools/archive/0.1.20.tar.gz -> samtools-0.1.20.tar.gz
-_eclasses_=multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=fa48f0b2be780a9264eb9d727ec53335
diff --git a/metadata/md5-cache/sci-biology/samtools-1.5 b/metadata/md5-cache/sci-biology/samtools-1.5
index 25f365c8f20c..3c4c881f14ce 100644
--- a/metadata/md5-cache/sci-biology/samtools-1.5
+++ b/metadata/md5-cache/sci-biology/samtools-1.5
@@ -1,14 +1,14 @@
 DEFINED_PHASES=install prepare test
-DEPEND=dev-lang/perl =sci-libs/htslib-1.5* sys-libs/ncurses:0= sys-libs/zlib python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] virtual/pkgconfig >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
+DEPEND=dev-lang/perl =sci-libs/htslib-1.5* sys-libs/ncurses:0= sys-libs/zlib python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] virtual/pkgconfig >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
 DESCRIPTION=Utilities for analysing and manipulating the SAM/BAM alignment formats
 EAPI=6
 HOMEPAGE=http://www.htslib.org/
 IUSE=examples python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=MIT
-RDEPEND=dev-lang/perl =sci-libs/htslib-1.5* sys-libs/ncurses:0= sys-libs/zlib python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=dev-lang/perl =sci-libs/htslib-1.5* sys-libs/ncurses:0= sys-libs/zlib python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=mirror://sourceforge/samtools/samtools-1.5.tar.bz2
-_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	libtool	f143db5a74ccd9ca28c1234deffede96	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	libtool	f143db5a74ccd9ca28c1234deffede96	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=8d92b4a814f62eab87bac2be22c2470c
diff --git a/metadata/md5-cache/sci-biology/seqan-1.4.2-r1 b/metadata/md5-cache/sci-biology/seqan-1.4.2-r1
index 35bfd2378a9e..38a203932c45 100644
--- a/metadata/md5-cache/sci-biology/seqan-1.4.2-r1
+++ b/metadata/md5-cache/sci-biology/seqan-1.4.2-r1
@@ -1,5 +1,5 @@
 DEFINED_PHASES=compile configure install postinst prepare setup test
-DEPEND=app-arch/bzip2 sys-libs/zlib test? ( || ( ( >=dev-lang/python-2.7.17-r1:2.7 dev-python/nose[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.17-r1:2.7 ) ) sys-devel/make >=dev-util/cmake-3.9.6
+DEPEND=app-arch/bzip2 sys-libs/zlib test? ( || ( ( >=dev-lang/python-2.7.5-r2:2.7 dev-python/nose[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.5-r2:2.7 ) ) sys-devel/make >=dev-util/cmake-3.9.6
 DESCRIPTION=C++ Sequence Analysis Library
 EAPI=6
 HOMEPAGE=http://www.seqan.de/
@@ -11,5 +11,5 @@ REQUIRED_USE=cpu_flags_x86_sse4_1
 RESTRICT=!test? ( test )
 SLOT=1.4
 SRC_URI=http://packages.seqan.de/seqan-src/seqan-src-1.4.2.tar.gz
-_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=1f1cf11ee07a7961e6fa23345e516b65
diff --git a/metadata/md5-cache/sci-biology/seqan-2.2.0-r1 b/metadata/md5-cache/sci-biology/seqan-2.2.0-r1
index ec2e860da44a..9a2fc8347f52 100644
--- a/metadata/md5-cache/sci-biology/seqan-2.2.0-r1
+++ b/metadata/md5-cache/sci-biology/seqan-2.2.0-r1
@@ -1,5 +1,5 @@
 DEFINED_PHASES=compile configure install prepare setup test
-DEPEND=app-arch/bzip2 sys-libs/zlib !!sci-biology/seqan:2.0 !!sci-biology/seqan:2.1 !!sci-biology/seqan:2.2 doc? ( || ( ( >=dev-lang/python-2.7.17-r1:2.7 dev-python/sphinx[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.17-r1:2.7 ) ) test? ( || ( ( >=dev-lang/python-2.7.17-r1:2.7 dev-python/nose[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.17-r1:2.7 ) ) sys-devel/make >=dev-util/cmake-3.9.6
+DEPEND=app-arch/bzip2 sys-libs/zlib !!sci-biology/seqan:2.0 !!sci-biology/seqan:2.1 !!sci-biology/seqan:2.2 doc? ( || ( ( >=dev-lang/python-2.7.5-r2:2.7 dev-python/sphinx[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.5-r2:2.7 ) ) test? ( || ( ( >=dev-lang/python-2.7.5-r2:2.7 dev-python/nose[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.5-r2:2.7 ) ) sys-devel/make >=dev-util/cmake-3.9.6
 DESCRIPTION=C++ Sequence Analysis Library
 EAPI=6
 HOMEPAGE=http://www.seqan.de/
@@ -11,5 +11,5 @@ REQUIRED_USE=cpu_flags_x86_sse4_1
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=http://packages.seqan.de/seqan-src/seqan-src-2.2.0.tar.gz
-_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=16bcf021b05ae673eb5878cdcefd8d8c
diff --git a/metadata/md5-cache/sci-biology/seqan-2.4.0 b/metadata/md5-cache/sci-biology/seqan-2.4.0
index 1ce2a5f10f76..73fce6c01471 100644
--- a/metadata/md5-cache/sci-biology/seqan-2.4.0
+++ b/metadata/md5-cache/sci-biology/seqan-2.4.0
@@ -1,5 +1,5 @@
 DEFINED_PHASES=compile configure install prepare setup test
-DEPEND=app-arch/bzip2:= sys-libs/zlib:= !!sci-biology/seqan:2.0 !!sci-biology/seqan:2.1 !!sci-biology/seqan:2.2 doc? ( || ( ( >=dev-lang/python-2.7.17-r1:2.7 dev-python/sphinx[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.17-r1:2.7 ) ) dev-util/ninja >=dev-util/cmake-3.9.6
+DEPEND=app-arch/bzip2:= sys-libs/zlib:= !!sci-biology/seqan:2.0 !!sci-biology/seqan:2.1 !!sci-biology/seqan:2.2 doc? ( || ( ( >=dev-lang/python-2.7.5-r2:2.7 dev-python/sphinx[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.5-r2:2.7 ) ) dev-util/ninja >=dev-util/cmake-3.9.6
 DESCRIPTION=C++ Sequence Analysis Library
 EAPI=6
 HOMEPAGE=http://www.seqan.de/
@@ -10,5 +10,5 @@ RDEPEND=app-arch/bzip2:= sys-libs/zlib:= !!sci-biology/seqan:2.0 !!sci-biology/s
 REQUIRED_USE=cpu_flags_x86_sse4_1
 SLOT=0
 SRC_URI=https://github.com/seqan/seqan/archive/seqan-v2.4.0.tar.gz
-_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	727554821dab8292d3a8198893c2ef8b	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=ca34cde2b2fc2f8692469a016bc077f6
diff --git a/metadata/md5-cache/sci-biology/seqan-9999 b/metadata/md5-cache/sci-biology/seqan-9999
index 35d5707c3aa3..6a420c92c826 100644
--- a/metadata/md5-cache/sci-biology/seqan-9999
+++ b/metadata/md5-cache/sci-biology/seqan-9999
@@ -1,5 +1,5 @@
 DEFINED_PHASES=compile configure install prepare setup test unpack
-DEPEND=app-arch/bzip2:= sys-libs/zlib:= !!sci-biology/seqan:2.0 !!sci-biology/seqan:2.1 !!sci-biology/seqan:2.2 doc? ( || ( ( >=dev-lang/python-2.7.17-r1:2.7 dev-python/sphinx[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.17-r1:2.7 ) ) dev-util/ninja >=dev-util/cmake-3.9.6 >=dev-vcs/git-1.8.2.1[curl]
+DEPEND=app-arch/bzip2:= sys-libs/zlib:= !!sci-biology/seqan:2.0 !!sci-biology/seqan:2.1 !!sci-biology/seqan:2.2 doc? ( || ( ( >=dev-lang/python-2.7.5-r2:2.7 dev-python/sphinx[python_targets_python2_7(-),python_single_target_python2_7(+)] ) ) || ( >=dev-lang/python-2.7.5-r2:2.7 ) ) dev-util/ninja >=dev-util/cmake-3.9.6 >=dev-vcs/git-1.8.2.1[curl]
 DESCRIPTION=C++ Sequence Analysis Library
 EAPI=6
 HOMEPAGE=http://www.seqan.de/
@@ -9,5 +9,5 @@ PROPERTIES=live
 RDEPEND=app-arch/bzip2:= sys-libs/zlib:= !!sci-biology/seqan:2.0 !!sci-biology/seqan:2.1 !!sci-biology/seqan:2.2
 REQUIRED_USE=cpu_flags_x86_sse4_1
 SLOT=0
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+_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	git-r3	86a0188f2ad9eb3d65e4d031ab8a0422	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=954c2a9b05e60f6a61eb27c1cc720117
diff --git a/metadata/md5-cache/sci-biology/shrimp-2.2.3 b/metadata/md5-cache/sci-biology/shrimp-2.2.3
index 685dabecd64a..3a9fb370a898 100644
--- a/metadata/md5-cache/sci-biology/shrimp-2.2.3
+++ b/metadata/md5-cache/sci-biology/shrimp-2.2.3
@@ -6,9 +6,9 @@ HOMEPAGE=http://compbio.cs.toronto.edu/shrimp/
 IUSE=custom-cflags +cpu_flags_x86_sse2 +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=shrimp
-RDEPEND=!sci-mathematics/cado-nfs python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+RDEPEND=!sci-mathematics/cado-nfs python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=http://compbio.cs.toronto.edu/shrimp/releases/SHRiMP_2_2_3.src.tar.gz
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+_eclasses_=desktop	7fd20552ce4cc97e8acb132a499a7dd8	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	f1194291b9a1baca337c1c89b5f7f365	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	318e8ae683e57fd3ccd0d31a769d8ee8	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	2d2617a730e75e491e1d17af87841ec5	python-utils-r1	dd532a387632f19bfc5523fc2289a9a0	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=98a7a2b9765ad5e245b1b7b9be67060b
diff --git a/metadata/md5-cache/sci-biology/vienna-rna-2.1.1 b/metadata/md5-cache/sci-biology/vienna-rna-2.1.1
index 2a71bb4c8c49..d5e43890989e 100644
--- a/metadata/md5-cache/sci-biology/vienna-rna-2.1.1
+++ b/metadata/md5-cache/sci-biology/vienna-rna-2.1.1
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare test unpack
-DEPEND=dev-lang/perl media-libs/gd doc? ( dev-texlive/texlive-latex ) python? ( python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) python? ( dev-lang/swig:0 ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4 dev-lang/perl:=[-build(-)]
+DEPEND=dev-lang/perl media-libs/gd doc? ( dev-texlive/texlive-latex ) python? ( python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) python? ( dev-lang/swig:0 ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4 dev-lang/perl:=[-build(-)]
 DESCRIPTION=RNA secondary structure prediction and comparison
 EAPI=5
 HOMEPAGE=http://www.tbi.univie.ac.at/~ivo/RNA/
 IUSE=doc openmp python static-libs python_targets_python2_7
 KEYWORDS=amd64 ppc x86
 LICENSE=vienna-rna
-RDEPEND=dev-lang/perl media-libs/gd doc? ( dev-texlive/texlive-latex ) python? ( python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) dev-lang/perl:=[-build(-)]
+RDEPEND=dev-lang/perl media-libs/gd doc? ( dev-texlive/texlive-latex ) python? ( python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) dev-lang/perl:=[-build(-)]
 REQUIRED_USE=python? ( || ( python_targets_python2_7 ) )
 SLOT=0
 SRC_URI=http://www.tbi.univie.ac.at/~ronny/RNA/ViennaRNA-2.1.1.tar.gz
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 _md5_=1e58c830b49ced05ae9960fcc2dead13
diff --git a/metadata/md5-cache/sci-biology/vienna-rna-2.1.8 b/metadata/md5-cache/sci-biology/vienna-rna-2.1.8
index 3dfc9282b98d..51581872b44d 100644
--- a/metadata/md5-cache/sci-biology/vienna-rna-2.1.8
+++ b/metadata/md5-cache/sci-biology/vienna-rna-2.1.8
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare test unpack
-DEPEND=dev-lang/perl media-libs/gd doc? ( dev-texlive/texlive-latex ) python? ( python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) python? ( dev-lang/swig:0 ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4 dev-lang/perl:=[-build(-)]
+DEPEND=dev-lang/perl media-libs/gd doc? ( dev-texlive/texlive-latex ) python? ( python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) python? ( dev-lang/swig:0 ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4 dev-lang/perl:=[-build(-)]
 DESCRIPTION=RNA secondary structure prediction and comparison
 EAPI=5
 HOMEPAGE=http://www.tbi.univie.ac.at/~ivo/RNA/
 IUSE=doc openmp python static-libs python_targets_python2_7
 KEYWORDS=~amd64 ~ppc ~x86
 LICENSE=vienna-rna
-RDEPEND=dev-lang/perl media-libs/gd doc? ( dev-texlive/texlive-latex ) python? ( python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) dev-lang/perl:=[-build(-)]
+RDEPEND=dev-lang/perl media-libs/gd doc? ( dev-texlive/texlive-latex ) python? ( python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) dev-lang/perl:=[-build(-)]
 REQUIRED_USE=python? ( || ( python_targets_python2_7 ) )
 SLOT=0
 SRC_URI=http://www.tbi.univie.ac.at/RNA/packages/source/ViennaRNA-2.1.8.tar.gz
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 _md5_=b2a6486af275e75c6365ab7eeba1e0bd