gentoo resync : 29.12.2022

author: V3n3RiX <venerix@koprulu.sector> 2022-06-29 12:04:12 +0100
committer: V3n3RiX <venerix@koprulu.sector> 2022-06-29 12:04:12 +0100
commit: 0f558761aa2dee1017b4751e4017205e015a9560 (patch)
tree: 037df795519468a25d9362b4e95cdaeb84eb1cf9 /metadata/md5-cache/sci-biology
parent: 752d6256e5204b958b0ef7905675a940b5e9172f (diff)
120 files changed, 274 insertions, 233 deletions
diff --git a/metadata/md5-cache/sci-biology/HTSeq-0.12.4 b/metadata/md5-cache/sci-biology/HTSeq-0.12.4
index 4d1c38842427..3c01f20f4b96 100644
--- a/metadata/md5-cache/sci-biology/HTSeq-0.12.4
+++ b/metadata/md5-cache/sci-biology/HTSeq-0.12.4
@@ -12,5 +12,5 @@ RDEPEND=dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 )
 SLOT=0
 SRC_URI=https://github.com/htseq/htseq/archive/release_0.12.4.tar.gz -> HTSeq-0.12.4.tar.gz
-_eclasses_=distutils-r1	3b871cf4724e3abc9b4ff059289f0d45	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-r1	8638751691200e941f26fe0ac3aef1d1	python-utils-r1	5dc84801daa87406aafaf535cb947a64	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=distutils-r1	10a93585889c3ca7651cbcd2ee831e47	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-r1	e2883e4f04f0503cdf7f2954e2bf5e15	python-utils-r1	648fe6a039e87233d7f48da72cadb76f	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=ae9941d3e3234244619fdcb2b46c8e90
diff --git a/metadata/md5-cache/sci-biology/HTSeq-9999 b/metadata/md5-cache/sci-biology/HTSeq-9999
index 0c8562b81561..e1b2d0e5b143 100644
--- a/metadata/md5-cache/sci-biology/HTSeq-9999
+++ b/metadata/md5-cache/sci-biology/HTSeq-9999
@@ -11,5 +11,5 @@ PROPERTIES=live
 RDEPEND=dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?] dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?] sci-biology/pysam[python_targets_python3_8(-)?,python_targets_python3_9(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 )
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 )
 SLOT=0
-_eclasses_=distutils-r1	3b871cf4724e3abc9b4ff059289f0d45	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	git-r3	b9ac6f96d2a88edb5b351df634dc5e53	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-r1	8638751691200e941f26fe0ac3aef1d1	python-utils-r1	5dc84801daa87406aafaf535cb947a64	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=distutils-r1	10a93585889c3ca7651cbcd2ee831e47	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	git-r3	b9ac6f96d2a88edb5b351df634dc5e53	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-r1	e2883e4f04f0503cdf7f2954e2bf5e15	python-utils-r1	648fe6a039e87233d7f48da72cadb76f	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=ae9941d3e3234244619fdcb2b46c8e90
diff --git a/metadata/md5-cache/sci-biology/Manifest.gz b/metadata/md5-cache/sci-biology/Manifest.gz
index 103ec1a965d2..6eb70f15b235 100644
--- a/metadata/md5-cache/sci-biology/Manifest.gz
+++ b/metadata/md5-cache/sci-biology/Manifest.gz
diff --git a/metadata/md5-cache/sci-biology/STAR-2.7.10a b/metadata/md5-cache/sci-biology/STAR-2.7.10a
index 71cbe1d3070e..094941fb89b2 100644
--- a/metadata/md5-cache/sci-biology/STAR-2.7.10a
+++ b/metadata/md5-cache/sci-biology/STAR-2.7.10a
@@ -10,5 +10,5 @@ LICENSE=GPL-3
 RDEPEND=sci-libs/htslib:=
 SLOT=0
 SRC_URI=https://github.com/alexdobin/STAR/archive/2.7.10a.tar.gz -> STAR-2.7.10a.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=521aed057c81cfa841ab4b2dcf63e65b
diff --git a/metadata/md5-cache/sci-biology/aaindex-9.1-r1 b/metadata/md5-cache/sci-biology/aaindex-9.1-r2
index 618805eb016b..6ba6ecc0082a 100644
--- a/metadata/md5-cache/sci-biology/aaindex-9.1-r1
+++ b/metadata/md5-cache/sci-biology/aaindex-9.1-r2
@@ -1,7 +1,7 @@
+BDEPEND=emboss? ( sci-biology/emboss )
 DEFINED_PHASES=compile install
-DEPEND=emboss? ( sci-biology/emboss )
 DESCRIPTION=Amino acid indices and similarity matrices
-EAPI=6
+EAPI=8
 HOMEPAGE=https://www.genome.jp/aaindex/
 IUSE=emboss minimal
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
@@ -9,4 +9,4 @@ LICENSE=public-domain
 RDEPEND=emboss? ( sci-biology/emboss )
 SLOT=0
 SRC_URI=mirror://gentoo/aaindex-9.1.tar.bz2
-_md5_=8636229aaffdb1c6d95611b06d3cd161
+_md5_=881d3a5590b0d557e474f7686f0ab42c
diff --git a/metadata/md5-cache/sci-biology/abyss-2.3.4 b/metadata/md5-cache/sci-biology/abyss-2.3.4
index 60bce26029b1..f754db4cdc31 100644
--- a/metadata/md5-cache/sci-biology/abyss-2.3.4
+++ b/metadata/md5-cache/sci-biology/abyss-2.3.4
@@ -4,11 +4,12 @@ DEPEND=dev-cpp/sparsehash dev-libs/boost:= misc-haskell? ( dev-libs/gmp:0= dev-l
 DESCRIPTION=Assembly By Short Sequences - a de novo, parallel, paired-end sequence assembler
 EAPI=8
 HOMEPAGE=https://www.bcgsc.ca/resources/software/abyss/
+INHERIT=autotools toolchain-funcs
 IUSE=openmp misc-haskell
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-3
 RDEPEND=dev-cpp/sparsehash dev-libs/boost:= misc-haskell? ( dev-libs/gmp:0= dev-libs/libffi:0= ) sys-cluster/openmpi dev-db/sqlite:3
 SLOT=0
 SRC_URI=https://github.com/bcgsc/abyss/archive/2.3.4.tar.gz -> abyss-2.3.4.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=9a708eff89b221551fbb0bcc299ccfa3
diff --git a/metadata/md5-cache/sci-biology/amap-2.2-r4 b/metadata/md5-cache/sci-biology/amap-2.2-r4
index c6b35d13ff51..48a186797165 100644
--- a/metadata/md5-cache/sci-biology/amap-2.2-r4
+++ b/metadata/md5-cache/sci-biology/amap-2.2-r4
@@ -10,5 +10,5 @@ LICENSE=GPL-2
 RDEPEND=java? ( >=virtual/jre-1.8:* ) java? ( >=dev-java/java-config-2.2.0-r3 )
 SLOT=0
 SRC_URI=http://baboon.math.berkeley.edu/amap/download/amap.2.2.tar.gz
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28	eapi7-ver	1a0a60ad07c8b32d2faba2d085dc0f24	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	java-ant-2	5cf479aa9e0ac9cc55899f2762c2aaa0	java-pkg-opt-2	a71433e535af8faae0c0f6c861a32054	java-utils-2	e38ea02d8ed864a74078ecf46aa06f30	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	versionator	d3fb3ba33acc3bbbdc4d7970227c100d	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=desktop	22952d8f27cac191d75529d4c38e6bfa	eapi7-ver	1a0a60ad07c8b32d2faba2d085dc0f24	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	java-ant-2	5cf479aa9e0ac9cc55899f2762c2aaa0	java-pkg-opt-2	a71433e535af8faae0c0f6c861a32054	java-utils-2	cfb5f6911bb70204c94ceafd0372c716	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	versionator	d3fb3ba33acc3bbbdc4d7970227c100d	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=857434504156a8892f1335babe24f9f0
diff --git a/metadata/md5-cache/sci-biology/augustus-2.5.5 b/metadata/md5-cache/sci-biology/augustus-2.5.5
index 475b45b98127..52582ced614b 100644
--- a/metadata/md5-cache/sci-biology/augustus-2.5.5
+++ b/metadata/md5-cache/sci-biology/augustus-2.5.5
@@ -2,10 +2,11 @@ DEFINED_PHASES=compile configure install
 DESCRIPTION=Eukaryotic gene predictor
 EAPI=7
 HOMEPAGE=http://augustus.gobics.de/
+INHERIT=toolchain-funcs
 IUSE=examples
 KEYWORDS=amd64 x86
 LICENSE=Artistic
 SLOT=0
 SRC_URI=http://augustus.gobics.de/binaries/augustus.2.5.5.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=80962b244c7531e320f35904727b5bd5
diff --git a/metadata/md5-cache/sci-biology/bamtools-2.5.2 b/metadata/md5-cache/sci-biology/bamtools-2.5.2
index fc6b49b34c9b..6107be36046e 100644
--- a/metadata/md5-cache/sci-biology/bamtools-2.5.2
+++ b/metadata/md5-cache/sci-biology/bamtools-2.5.2
@@ -1,4 +1,4 @@
-BDEPEND=virtual/pkgconfig dev-util/ninja >=dev-util/cmake-3.20.5
+BDEPEND=virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install prepare test
 DEPEND=>=dev-libs/jsoncpp-1.8.0:= sys-libs/zlib:=
 DESCRIPTION=A programmer's API and an end-user's toolkit for handling BAM files
@@ -10,5 +10,5 @@ LICENSE=MIT
 RDEPEND=>=dev-libs/jsoncpp-1.8.0:= sys-libs/zlib:=
 SLOT=0/2.5.2
 SRC_URI=https://github.com/pezmaster31/bamtools/archive/v2.5.2.tar.gz -> bamtools-2.5.2.tar.gz
-_eclasses_=cmake	90e2b29417d53718328f3a95227137a0	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
+_eclasses_=cmake	44afbf15c35884f7c840470f1cf05d0d	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
 _md5_=efdfbdbf4181a018ee9965d5c16be71f
diff --git a/metadata/md5-cache/sci-biology/bamtools-9999 b/metadata/md5-cache/sci-biology/bamtools-9999
index e3abb5a825ed..82af37e192ee 100644
--- a/metadata/md5-cache/sci-biology/bamtools-9999
+++ b/metadata/md5-cache/sci-biology/bamtools-9999
@@ -1,4 +1,4 @@
-BDEPEND=virtual/pkgconfig dev-util/ninja >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install prepare test unpack
 DEPEND=>=dev-libs/jsoncpp-1.8.0:= sys-libs/zlib:=
 DESCRIPTION=A programmer's API and an end-user's toolkit for handling BAM files
@@ -9,5 +9,5 @@ LICENSE=MIT
 PROPERTIES=live
 RDEPEND=>=dev-libs/jsoncpp-1.8.0:= sys-libs/zlib:=
 SLOT=0/9999
-_eclasses_=cmake	90e2b29417d53718328f3a95227137a0	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	git-r3	b9ac6f96d2a88edb5b351df634dc5e53	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
+_eclasses_=cmake	44afbf15c35884f7c840470f1cf05d0d	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	git-r3	b9ac6f96d2a88edb5b351df634dc5e53	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
 _md5_=a2299dc6ca850c1c25582656d7586681
diff --git a/metadata/md5-cache/sci-biology/bcftools-1.15 b/metadata/md5-cache/sci-biology/bcftools-1.15
deleted file mode 100644
index c2dce0ab8942..000000000000
--- a/metadata/md5-cache/sci-biology/bcftools-1.15
+++ /dev/null
@@ -1,16 +0,0 @@
-BDEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 )
-DEFINED_PHASES=configure prepare setup
-DEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.15*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 )
-DESCRIPTION=Utilities for variant calling and manipulating VCF and BCF files
-EAPI=8
-HOMEPAGE=http://www.htslib.org
-INHERIT=python-single-r1
-IUSE=python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10
-KEYWORDS=~amd64 ~x86
-LICENSE=MIT
-RDEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.15*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 )
-REQUIRED_USE=^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 )
-SLOT=0
-SRC_URI=https://github.com/samtools/bcftools/releases/download/1.15/bcftools-1.15.tar.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	5dc84801daa87406aafaf535cb947a64	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
-_md5_=2b2091a43195aec58a417e5334bfa2fc
diff --git a/metadata/md5-cache/sci-biology/bcftools-1.13 b/metadata/md5-cache/sci-biology/bcftools-1.15.1
index 18de037e70c2..9bc416ae1125 100644
--- a/metadata/md5-cache/sci-biology/bcftools-1.13
+++ b/metadata/md5-cache/sci-biology/bcftools-1.15.1
@@ -1,6 +1,6 @@
 BDEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 )
 DEFINED_PHASES=configure prepare setup
-DEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.13*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 )
+DEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.15.1*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 )
 DESCRIPTION=Utilities for variant calling and manipulating VCF and BCF files
 EAPI=8
 HOMEPAGE=http://www.htslib.org
@@ -8,9 +8,9 @@ INHERIT=python-single-r1
 IUSE=python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10
 KEYWORDS=~amd64 ~x86
 LICENSE=MIT
-RDEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.13*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 )
+RDEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.15.1*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 )
 REQUIRED_USE=^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 )
 SLOT=0
-SRC_URI=https://github.com/samtools/bcftools/releases/download/1.13/bcftools-1.13.tar.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	5dc84801daa87406aafaf535cb947a64	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
-_md5_=a7d6aa14a25dfbfd5fa4547dea06070c
+SRC_URI=https://github.com/samtools/bcftools/releases/download/1.15.1/bcftools-1.15.1.tar.bz2
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	648fe6a039e87233d7f48da72cadb76f	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
+_md5_=a991b200539f7c26af7f584fe62e90f5
diff --git a/metadata/md5-cache/sci-biology/bedtools-2.30.0 b/metadata/md5-cache/sci-biology/bedtools-2.30.0
index 5e26675ace14..fab2aa2e9e4e 100644
--- a/metadata/md5-cache/sci-biology/bedtools-2.30.0
+++ b/metadata/md5-cache/sci-biology/bedtools-2.30.0
@@ -12,5 +12,5 @@ RDEPEND=app-arch/bzip2 app-arch/xz-utils sys-libs/zlib
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/arq5x/bedtools2/releases/download/v2.30.0/bedtools-2.30.0.tar.gz
-_eclasses_=eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-any-r1	9006edf4b9c90f9ba1dc9ea9fee1b0bd	python-utils-r1	5dc84801daa87406aafaf535cb947a64	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-any-r1	a3e9c0524a795d7f2767a2cf12a2e8c0	python-utils-r1	648fe6a039e87233d7f48da72cadb76f	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=14bf1e3697276975f4e8b47a297b1bf5
diff --git a/metadata/md5-cache/sci-biology/bfast-0.7.0a b/metadata/md5-cache/sci-biology/bfast-0.7.0a
index beda105a62b0..688e20431a7c 100644
--- a/metadata/md5-cache/sci-biology/bfast-0.7.0a
+++ b/metadata/md5-cache/sci-biology/bfast-0.7.0a
@@ -3,6 +3,7 @@ DEFINED_PHASES=prepare
 DESCRIPTION=Blat-like Fast Accurate Search Tool
 EAPI=7
 HOMEPAGE=https://sourceforge.net/projects/bfast/
+INHERIT=autotools
 IUSE=test
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
@@ -10,5 +11,5 @@ RDEPEND=dev-perl/XML-Simple
 RESTRICT=test
 SLOT=0
 SRC_URI=mirror://sourceforge/bfast/bfast-0.7.0a.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=e64abecddb86e9860edc80410f299d83
diff --git a/metadata/md5-cache/sci-biology/biogrep-1.0-r2 b/metadata/md5-cache/sci-biology/biogrep-1.0-r2
index 06ae0ae14a63..08808dbdd644 100644
--- a/metadata/md5-cache/sci-biology/biogrep-1.0-r2
+++ b/metadata/md5-cache/sci-biology/biogrep-1.0-r2
@@ -9,5 +9,5 @@ KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=http://www.openwetware.org/images/3/3d/Biogrep-1.0.tar.gz -> biogrep-1.0.tar.gz doc? ( http://www.openwetware.org/images/4/49/Biogrep.pdf -> biogrep-1.0.pdf )
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=9731727dae2a2514bcaa486b0059272e
diff --git a/metadata/md5-cache/sci-biology/biopandas-0.2.7 b/metadata/md5-cache/sci-biology/biopandas-0.2.7
index 9abd60aaffe3..157de29dd193 100644
--- a/metadata/md5-cache/sci-biology/biopandas-0.2.7
+++ b/metadata/md5-cache/sci-biology/biopandas-0.2.7
@@ -12,5 +12,5 @@ REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 )
 RESTRICT=!test? ( test ) !test? ( test )
 SLOT=0
 SRC_URI=mirror://pypi/B/BioPandas/biopandas-0.2.7.tar.gz
-_eclasses_=distutils-r1	3b871cf4724e3abc9b4ff059289f0d45	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-r1	8638751691200e941f26fe0ac3aef1d1	python-utils-r1	5dc84801daa87406aafaf535cb947a64	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=distutils-r1	10a93585889c3ca7651cbcd2ee831e47	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-r1	e2883e4f04f0503cdf7f2954e2bf5e15	python-utils-r1	648fe6a039e87233d7f48da72cadb76f	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=6e4b8600d4f3c3ac26b099a9c4577ca0
diff --git a/metadata/md5-cache/sci-biology/biopython-1.79 b/metadata/md5-cache/sci-biology/biopython-1.79
index b250703d720d..a49efa928d5a 100644
--- a/metadata/md5-cache/sci-biology/biopython-1.79
+++ b/metadata/md5-cache/sci-biology/biopython-1.79
@@ -12,5 +12,5 @@ RDEPEND=dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python
 REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
 SLOT=0
 SRC_URI=mirror://pypi/b/biopython/biopython-1.79.tar.gz
-_eclasses_=distutils-r1	3b871cf4724e3abc9b4ff059289f0d45	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	optfeature	d524f291c80f9d21ad80fe978e3ca760	python-r1	8638751691200e941f26fe0ac3aef1d1	python-utils-r1	5dc84801daa87406aafaf535cb947a64	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
-_md5_=4e2a43ec127b152970bd1c43306e9418
+_eclasses_=distutils-r1	10a93585889c3ca7651cbcd2ee831e47	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	optfeature	d524f291c80f9d21ad80fe978e3ca760	python-r1	e2883e4f04f0503cdf7f2954e2bf5e15	python-utils-r1	648fe6a039e87233d7f48da72cadb76f	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
+_md5_=89d2124a2c9f76eda9c399f23c96a8b8
diff --git a/metadata/md5-cache/sci-biology/blat-34-r2 b/metadata/md5-cache/sci-biology/blat-34-r2
index d33a5f151ebf..f059302301d8 100644
--- a/metadata/md5-cache/sci-biology/blat-34-r2
+++ b/metadata/md5-cache/sci-biology/blat-34-r2
@@ -3,9 +3,10 @@ DEPEND=app-arch/unzip
 DESCRIPTION=The BLAST-Like Alignment Tool, a fast genomic sequence aligner
 EAPI=6
 HOMEPAGE=http://www.cse.ucsc.edu/~kent/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=blat
 SLOT=0
 SRC_URI=http://www.soe.ucsc.edu/~kent/src/blatSrc34.zip
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=9fb0b819fe1d2fa16c86c748d885fc84
diff --git a/metadata/md5-cache/sci-biology/bowtie-2.4.4 b/metadata/md5-cache/sci-biology/bowtie-2.4.4
index f5ca79e86148..5ef261c838d1 100644
--- a/metadata/md5-cache/sci-biology/bowtie-2.4.4
+++ b/metadata/md5-cache/sci-biology/bowtie-2.4.4
@@ -12,5 +12,5 @@ RDEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) p
 REQUIRED_USE=cpu_flags_x86_sse2 ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 )
 SLOT=2
 SRC_URI=mirror://sourceforge/project/bowtie-bio/bowtie2/2.4.4/bowtie2-2.4.4-source.zip
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	5dc84801daa87406aafaf535cb947a64	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	python-utils-r1	648fe6a039e87233d7f48da72cadb76f	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=a169406c93e64d9cae6cbb8ad262f62b
diff --git a/metadata/md5-cache/sci-biology/bwa-0.7.17 b/metadata/md5-cache/sci-biology/bwa-0.7.17
index 284063a43466..585c0a067d4a 100644
--- a/metadata/md5-cache/sci-biology/bwa-0.7.17
+++ b/metadata/md5-cache/sci-biology/bwa-0.7.17
@@ -3,10 +3,11 @@ DEPEND=sys-libs/zlib
 DESCRIPTION=Burrows-Wheeler Alignment Tool, a fast short genomic sequence aligner
 EAPI=7
 HOMEPAGE=https://github.com/lh3/bwa/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86 ~x64-macos
 LICENSE=GPL-3
 RDEPEND=sys-libs/zlib dev-lang/perl
 SLOT=0
 SRC_URI=https://github.com/lh3/bwa/archive/v0.7.17.tar.gz -> bwa-0.7.17.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=620c3569e8293303737f7844385c7e82
diff --git a/metadata/md5-cache/sci-biology/cd-hit-4.6.6 b/metadata/md5-cache/sci-biology/cd-hit-4.6.6
index bda89bdcc232..eeaa83c15f5e 100644
--- a/metadata/md5-cache/sci-biology/cd-hit-4.6.6
+++ b/metadata/md5-cache/sci-biology/cd-hit-4.6.6
@@ -9,5 +9,5 @@ LICENSE=GPL-2
 RDEPEND=dev-lang/perl
 SLOT=0
 SRC_URI=https://github.com/weizhongli/cdhit/releases/download/V4.6.6/cd-hit-v4.6.6-2016-0711.tar.gz -> cd-hit-4.6.6.tar.gz
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=bbe0ae10275a73485487e08f19f4ac1b
diff --git a/metadata/md5-cache/sci-biology/clustal-omega-1.2.4 b/metadata/md5-cache/sci-biology/clustal-omega-1.2.4
index 50dca567ec7b..b7f312ff11b9 100644
--- a/metadata/md5-cache/sci-biology/clustal-omega-1.2.4
+++ b/metadata/md5-cache/sci-biology/clustal-omega-1.2.4
@@ -10,5 +10,5 @@ LICENSE=GPL-2
 RDEPEND=dev-libs/argtable
 SLOT=0
 SRC_URI=http://www.clustal.org/omega/clustal-omega-1.2.4.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=9ade45d2e283bc5fcc7eef16725e18ae
diff --git a/metadata/md5-cache/sci-biology/clustalw-1.83-r4 b/metadata/md5-cache/sci-biology/clustalw-1.83-r4
index 23c2f3a9fc55..6616885bb2b3 100644
--- a/metadata/md5-cache/sci-biology/clustalw-1.83-r4
+++ b/metadata/md5-cache/sci-biology/clustalw-1.83-r4
@@ -2,9 +2,10 @@ DEFINED_PHASES=install prepare
 DESCRIPTION=General purpose multiple alignment program for DNA and proteins
 EAPI=6
 HOMEPAGE=http://www.embl-heidelberg.de/~seqanal/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 ~ppc ppc64 sparc x86 ~amd64-linux ~x86-linux ~ppc-macos ~sparc-solaris
 LICENSE=clustalw
 SLOT=1
 SRC_URI=ftp://ftp.ebi.ac.uk/pub/software/unix/clustalw/clustalw1.83.UNIX.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=0bc3b2f2f4e07f1d81ee076b0fbe6c60
diff --git a/metadata/md5-cache/sci-biology/clustalw-mpi-0.13-r3 b/metadata/md5-cache/sci-biology/clustalw-mpi-0.13-r3
index d521c2906fdb..1a9e9e12372e 100644
--- a/metadata/md5-cache/sci-biology/clustalw-mpi-0.13-r3
+++ b/metadata/md5-cache/sci-biology/clustalw-mpi-0.13-r3
@@ -3,11 +3,12 @@ DEPEND=virtual/mpi
 DESCRIPTION=An MPI implemention of the ClustalW general purpose multiple alignment algorithm
 EAPI=7
 HOMEPAGE=http://www.bii.a-star.edu.sg/achievements/applications/clustalw/index.php
+INHERIT=toolchain-funcs
 IUSE=mpi-njtree static-pairalign
 KEYWORDS=~amd64 ~x86
 LICENSE=public-domain
 RDEPEND=virtual/mpi
 SLOT=0
 SRC_URI=http://web.bii.a-star.edu.sg/~kuobin/clustalw-mpi/clustalw-mpi-0.13.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=689841db0e3b7d6629b51049a2942165
diff --git a/metadata/md5-cache/sci-biology/clustalx-2.1-r3 b/metadata/md5-cache/sci-biology/clustalx-2.1-r3
index 5459284860a9..9bd6e79e604f 100644
--- a/metadata/md5-cache/sci-biology/clustalx-2.1-r3
+++ b/metadata/md5-cache/sci-biology/clustalx-2.1-r3
@@ -9,5 +9,5 @@ LICENSE=GPL-3 LGPL-3
 RDEPEND=dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtwidgets:5 dev-qt/qtxml:5 >=sci-biology/clustalw-2.1
 SLOT=0
 SRC_URI=http://www.clustal.org/download/current/clustalx-2.1.tar.gz https://dev.gentoo.org/~jlec/distfiles/clustalx.png.xz
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	qmake-utils	59420c906278d16deaaa629f9d115707	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=desktop	22952d8f27cac191d75529d4c38e6bfa	multilib	4fbbbc98f236f1b43acd99476bc3cd85	qmake-utils	59420c906278d16deaaa629f9d115707	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=3f60f1952758458fc3cd4e2789a942f5
diff --git a/metadata/md5-cache/sci-biology/consed-29 b/metadata/md5-cache/sci-biology/consed-29
index b7e62081cec8..d9ae32363001 100644
--- a/metadata/md5-cache/sci-biology/consed-29
+++ b/metadata/md5-cache/sci-biology/consed-29
@@ -11,5 +11,5 @@ RDEPEND=x11-libs/libX11 x11-libs/motif:0 sci-biology/samtools:0.1-legacy dev-lan
 RESTRICT=fetch
 SLOT=0
 SRC_URI=consed-29-sources.tar.gz consed-29-linux.tar.gz
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=1e30f1827727dab34c75c8c026745369
diff --git a/metadata/md5-cache/sci-biology/cutg-160-r1 b/metadata/md5-cache/sci-biology/cutg-160-r1
index 014099bad9f1..439eebf601f7 100644
--- a/metadata/md5-cache/sci-biology/cutg-160-r1
+++ b/metadata/md5-cache/sci-biology/cutg-160-r1
@@ -10,4 +10,4 @@ RDEPEND=emboss? ( sci-biology/emboss )
 RESTRICT=binchecks strip
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/cutg-160.tar.xz
-_md5_=b2140a376a1ceedf750f2cdd153309cf
+_md5_=f85abfb1030988c2814b5f00d0d171b0
diff --git a/metadata/md5-cache/sci-biology/dialign-tx-1.0.2-r2 b/metadata/md5-cache/sci-biology/dialign-tx-1.0.2-r2
index 1b031a187b98..9e36b8985be4 100644
--- a/metadata/md5-cache/sci-biology/dialign-tx-1.0.2-r2
+++ b/metadata/md5-cache/sci-biology/dialign-tx-1.0.2-r2
@@ -2,9 +2,10 @@ DEFINED_PHASES=compile configure install postinst
 DESCRIPTION=Greedy and progressive approaches for segment-based multiple sequence alignment
 EAPI=7
 HOMEPAGE=http://dialign-tx.gobics.de/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=LGPL-2.1
 SLOT=0
 SRC_URI=http://dialign-tx.gobics.de/DIALIGN-TX_1.0.2.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=b2a78c4cfa60eb348ae63d076ecb5fba
diff --git a/metadata/md5-cache/sci-biology/dialign2-2.2.1 b/metadata/md5-cache/sci-biology/dialign2-2.2.1
index e644593b97d8..a8d66d62dd0f 100644
--- a/metadata/md5-cache/sci-biology/dialign2-2.2.1
+++ b/metadata/md5-cache/sci-biology/dialign2-2.2.1
@@ -7,5 +7,5 @@ KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=LGPL-2.1
 SLOT=0
 SRC_URI=http://bibiserv.techfak.uni-bielefeld.de/applications/dialign/resources/downloads/dialign-2.2.1-src.tar.gz
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=3761a69a47f38308f54ae0b051361ed6
diff --git a/metadata/md5-cache/sci-biology/elph-1.0.1-r1 b/metadata/md5-cache/sci-biology/elph-1.0.1-r1
index 4edfa625bab8..2886618e63da 100644
--- a/metadata/md5-cache/sci-biology/elph-1.0.1-r1
+++ b/metadata/md5-cache/sci-biology/elph-1.0.1-r1
@@ -2,9 +2,10 @@ DEFINED_PHASES=configure install
 DESCRIPTION=Estimated Locations of Pattern Hits - Motif finder program
 EAPI=6
 HOMEPAGE=http://cbcb.umd.edu/software/ELPH/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~ppc-macos
 LICENSE=Artistic
 SLOT=0
 SRC_URI=ftp://ftp.cbcb.umd.edu/pub/software/elph/ELPH-1.0.1.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=dbee2f511488caf9eadadb20d043a2da
diff --git a/metadata/md5-cache/sci-biology/embassy-cbstools-1.0.0.660-r1 b/metadata/md5-cache/sci-biology/embassy-cbstools-1.0.0.660-r1
index 71800c1fa506..10d55ccff044 100644
--- a/metadata/md5-cache/sci-biology/embassy-cbstools-1.0.0.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-cbstools-1.0.0.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of Applications from the CBS group
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/CBSTOOLS-1.0.0.660.tar.gz -> embassy-cbstools-1.0.0.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=56469e1c3bb7c4baac8ad99638b59ff0
diff --git a/metadata/md5-cache/sci-biology/embassy-clustalomega-1.1.0.660-r1 b/metadata/md5-cache/sci-biology/embassy-clustalomega-1.1.0.660-r1
index dd5fb76df3fd..d4cf7b557344 100644
--- a/metadata/md5-cache/sci-biology/embassy-clustalomega-1.1.0.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-clustalomega-1.1.0.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of Clustal Omega - Multiple Sequence Alignment
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=sci-biology/clustal-omega dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/CLUSTALOMEGA-1.1.0.660.tar.gz -> embassy-clustalomega-1.1.0.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=864a13621791118f794da4601dcde749
diff --git a/metadata/md5-cache/sci-biology/embassy-domainatrix-0.1.660-r1 b/metadata/md5-cache/sci-biology/embassy-domainatrix-0.1.660-r1
index c98f800555d3..6d5257dce61d 100644
--- a/metadata/md5-cache/sci-biology/embassy-domainatrix-0.1.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-domainatrix-0.1.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of Protein domain analysis add-on package
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/DOMAINATRIX-0.1.660.tar.gz -> embassy-domainatrix-0.1.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=af29c98cab7134ba05c6d874e37d95dc
diff --git a/metadata/md5-cache/sci-biology/embassy-domalign-0.1.660-r1 b/metadata/md5-cache/sci-biology/embassy-domalign-0.1.660-r1
index add209e7262a..177bf066ef83 100644
--- a/metadata/md5-cache/sci-biology/embassy-domalign-0.1.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-domalign-0.1.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of Protein domain alignment add-on package
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/DOMALIGN-0.1.660.tar.gz -> embassy-domalign-0.1.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=677a5e171c80e94969c1ab9c0b55e283
diff --git a/metadata/md5-cache/sci-biology/embassy-domsearch-0.1.660-r1 b/metadata/md5-cache/sci-biology/embassy-domsearch-0.1.660-r1
index 50fcf2b70f0e..9e079f2b506f 100644
--- a/metadata/md5-cache/sci-biology/embassy-domsearch-0.1.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-domsearch-0.1.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of Protein domain search add-on package
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/DOMSEARCH-0.1.660.tar.gz -> embassy-domsearch-0.1.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=e0ca10c2776835b0cd20c1b0f0721a1a
diff --git a/metadata/md5-cache/sci-biology/embassy-emnu-1.05.660-r1 b/metadata/md5-cache/sci-biology/embassy-emnu-1.05.660-r1
index 4450b0a5fd04..2a7cd9a0be6c 100644
--- a/metadata/md5-cache/sci-biology/embassy-emnu-1.05.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-emnu-1.05.660-r1
@@ -4,11 +4,12 @@ DEPEND=sys-libs/ncurses:0= dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= s
 DESCRIPTION=EMBOSS integrated version of Simple menu of EMBOSS applications
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=sys-libs/ncurses:0= dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/EMNU-1.05.660.tar.gz -> embassy-emnu-1.05.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=a33d45b5be798e7ebfcef8c59a300c88
diff --git a/metadata/md5-cache/sci-biology/embassy-esim4-1.0.0.660-r1 b/metadata/md5-cache/sci-biology/embassy-esim4-1.0.0.660-r1
index 0fa3e24ef873..cdbfd38e32c5 100644
--- a/metadata/md5-cache/sci-biology/embassy-esim4-1.0.0.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-esim4-1.0.0.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of sim4 - Alignment of cDNA and genomic DNA
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/ESIM4-1.0.0.660.tar.gz -> embassy-esim4-1.0.0.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=95026ca22c2bacedf52a70b4428e7753
diff --git a/metadata/md5-cache/sci-biology/embassy-hmmer-2.3.2.660-r1 b/metadata/md5-cache/sci-biology/embassy-hmmer-2.3.2.660-r1
index 2fcce8122664..f5f2d34fcc60 100644
--- a/metadata/md5-cache/sci-biology/embassy-hmmer-2.3.2.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-hmmer-2.3.2.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of HMMER wrapper - sequence analysis with profile HMMs
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=sci-biology/hmmer:2 dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/HMMER-2.3.2.660.tar.gz -> embassy-hmmer-2.3.2.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=fb64fb071ec661ab550e0b33bc78b536
diff --git a/metadata/md5-cache/sci-biology/embassy-iprscan-4.3.1.660-r1 b/metadata/md5-cache/sci-biology/embassy-iprscan-4.3.1.660-r1
index b072308440ac..cced827d3eaf 100644
--- a/metadata/md5-cache/sci-biology/embassy-iprscan-4.3.1.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-iprscan-4.3.1.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of InterProScan motif detection add-on package
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/IPRSCAN-4.3.1.660.tar.gz -> embassy-iprscan-4.3.1.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=06b3cb4ecb53ada6b96c0f8fe91680e9
diff --git a/metadata/md5-cache/sci-biology/embassy-mse-3.0.0.660-r1 b/metadata/md5-cache/sci-biology/embassy-mse-3.0.0.660-r1
index 386cf6cc9f8d..4303277ccdc0 100644
--- a/metadata/md5-cache/sci-biology/embassy-mse-3.0.0.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-mse-3.0.0.660-r1
@@ -4,11 +4,12 @@ DEPEND=sys-libs/ncurses:= dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sy
 DESCRIPTION=EMBOSS integrated version of MSE - Multiple Sequence Screen Editor
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=sys-libs/ncurses:= dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/MSE-3.0.0.660.tar.gz -> embassy-mse-3.0.0.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=b6d66fbfe89f6c64f635551357dc90f4
diff --git a/metadata/md5-cache/sci-biology/embassy-phylipnew-3.69.660-r1 b/metadata/md5-cache/sci-biology/embassy-phylipnew-3.69.660-r1
index 4279a18be629..f12cc0af0050 100644
--- a/metadata/md5-cache/sci-biology/embassy-phylipnew-3.69.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-phylipnew-3.69.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of The Phylogeny Inference Package
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2 free-noncomm
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/PHYLIPNEW-3.69.660.tar.gz -> embassy-phylipnew-3.69.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=93c762366f9cfe8fbfdffd0fdc0483d5
diff --git a/metadata/md5-cache/sci-biology/embassy-signature-0.1.660-r1 b/metadata/md5-cache/sci-biology/embassy-signature-0.1.660-r1
index 978cc14dc4de..8fc16177c7b0 100644
--- a/metadata/md5-cache/sci-biology/embassy-signature-0.1.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-signature-0.1.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of Protein signature add-on package
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/SIGNATURE-0.1.660.tar.gz -> embassy-signature-0.1.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=193e23282bfd7f7751d7e37988a0ec44
diff --git a/metadata/md5-cache/sci-biology/embassy-structure-0.1.660-r1 b/metadata/md5-cache/sci-biology/embassy-structure-0.1.660-r1
index 0f5b0658c7ae..06c20cb10683 100644
--- a/metadata/md5-cache/sci-biology/embassy-structure-0.1.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-structure-0.1.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of Protein structure add-on package
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/STRUCTURE-0.1.660.tar.gz -> embassy-structure-0.1.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=c54138383c80476f9d515e5e2a33acaf
diff --git a/metadata/md5-cache/sci-biology/embassy-topo-2.0.660-r1 b/metadata/md5-cache/sci-biology/embassy-topo-2.0.660-r1
index 922b7af0a4f5..b61c57001d8b 100644
--- a/metadata/md5-cache/sci-biology/embassy-topo-2.0.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-topo-2.0.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of Transmembrane protein display
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/TOPO-2.0.660.tar.gz -> embassy-topo-2.0.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=30ddf1c7471e11d692477ffa5a3a9956
diff --git a/metadata/md5-cache/sci-biology/embassy-vienna-1.7.2.660-r1 b/metadata/md5-cache/sci-biology/embassy-vienna-1.7.2.660-r1
index 738438195736..abd7243e1690 100644
--- a/metadata/md5-cache/sci-biology/embassy-vienna-1.7.2.660-r1
+++ b/metadata/md5-cache/sci-biology/embassy-vienna-1.7.2.660-r1
@@ -4,11 +4,12 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=EMBOSS integrated version of Vienna RNA package - RNA folding
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3
 IUSE=mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=LGPL-2 GPL-2
 RDEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt ) >=sci-biology/emboss-6.6.0-r1[mysql=,pdf=,png=,postgres=,X=]
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/VIENNA-1.7.2.660.tar.gz -> embassy-vienna-1.7.2.660.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=ba0cdfe4fa4ef35b15cb45a53f81f3b7
diff --git a/metadata/md5-cache/sci-biology/emboss-6.6.0-r2 b/metadata/md5-cache/sci-biology/emboss-6.6.0-r2
index e7fb978de95f..8619727c1291 100644
--- a/metadata/md5-cache/sci-biology/emboss-6.6.0-r2
+++ b/metadata/md5-cache/sci-biology/emboss-6.6.0-r2
@@ -4,6 +4,7 @@ DEPEND=dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql?
 DESCRIPTION=The European Molecular Biology Open Software Suite - A sequence analysis package
 EAPI=8
 HOMEPAGE=http://emboss.sourceforge.net/
+INHERIT=autotools emboss-r3 readme.gentoo-r1
 IUSE=minimal mysql pdf png postgres X
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=LGPL-2 GPL-2 Apache-2.0 GPL-3+ CC-BY-3.0
@@ -11,5 +12,5 @@ PDEPEND=!minimal? ( sci-biology/aaindex sci-biology/cutg sci-biology/primer3 sci
 RDEPEND=!games-action/xbomber !sys-devel/cons dev-libs/expat dev-libs/libpcre:3 sci-libs/plplot:= sys-libs/zlib mysql? ( dev-db/mysql-connector-c:0= ) pdf? ( media-libs/libharu:= ) png? ( media-libs/gd:2=[png] ) postgres? ( dev-db/postgresql:= ) X? ( x11-libs/libXt )
 SLOT=0
 SRC_URI=ftp://emboss.open-bio.org/pub/EMBOSS/EMBOSS-6.6.0.tar.gz https://dev.gentoo.org/~soap/distfiles/emboss-6.6.0-patches-r1.tar.xz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	emboss-r3	ed4c0b270092039c992b771a26ca322a	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=9856dbbe227d34ba8fd5a46c30dc912f
diff --git a/metadata/md5-cache/sci-biology/eugene-4.1d b/metadata/md5-cache/sci-biology/eugene-4.1d
index 8bcf01bad788..b8cd28293f13 100644
--- a/metadata/md5-cache/sci-biology/eugene-4.1d
+++ b/metadata/md5-cache/sci-biology/eugene-4.1d
@@ -10,5 +10,5 @@ RDEPEND=media-libs/gd[png] media-libs/libpng:0=
 RESTRICT=test
 SLOT=0
 SRC_URI=https://mulcyber.toulouse.inra.fr/frs/download.php/1359/eugene-4.1d.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=683d1e7f9daeda6cd20b92117330ea81
diff --git a/metadata/md5-cache/sci-biology/exonerate-2.2.0-r2 b/metadata/md5-cache/sci-biology/exonerate-2.2.0-r2
index f5648549c8f4..203901830e49 100644
--- a/metadata/md5-cache/sci-biology/exonerate-2.2.0-r2
+++ b/metadata/md5-cache/sci-biology/exonerate-2.2.0-r2
@@ -12,5 +12,5 @@ REQUIRED_USE=test? ( utils )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=http://ftp.ebi.ac.uk/pub/software/vertebrategenomics/exonerate/exonerate-2.2.0.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=05c99b447503c7a3fae4594cd126939a
diff --git a/metadata/md5-cache/sci-biology/express-1.5.1 b/metadata/md5-cache/sci-biology/express-1.5.1
index e05154cd349f..76405a494802 100644
--- a/metadata/md5-cache/sci-biology/express-1.5.1
+++ b/metadata/md5-cache/sci-biology/express-1.5.1
@@ -1,4 +1,4 @@
-BDEPEND=dev-util/ninja >=dev-util/cmake-3.20.5
+BDEPEND=>=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install prepare test
 DEPEND=>=dev-libs/boost-1.52.0:= dev-libs/protobuf dev-util/google-perftools sci-biology/bamtools sys-libs/zlib
 DESCRIPTION=Streaming RNA-Seq Analysis
@@ -10,5 +10,5 @@ LICENSE=Artistic
 RDEPEND=>=dev-libs/boost-1.52.0:= dev-libs/protobuf dev-util/google-perftools sci-biology/bamtools sys-libs/zlib
 SLOT=0
 SRC_URI=https://pachterlab.github.io/eXpress/downloads/express-1.5.1/express-1.5.1-src.tgz
-_eclasses_=cmake	90e2b29417d53718328f3a95227137a0	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
+_eclasses_=cmake	44afbf15c35884f7c840470f1cf05d0d	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
 _md5_=b4fcbc714ea460615318f4baa4bc347a
diff --git a/metadata/md5-cache/sci-biology/fasta-36.3.8h-r1 b/metadata/md5-cache/sci-biology/fasta-36.3.8h-r1
index b9150daadeb6..e8e9dbcf89bb 100644
--- a/metadata/md5-cache/sci-biology/fasta-36.3.8h-r1
+++ b/metadata/md5-cache/sci-biology/fasta-36.3.8h-r1
@@ -3,11 +3,12 @@ DEFINED_PHASES=compile install prepare test
 DESCRIPTION=FASTA is a DNA and Protein sequence alignment software package
 EAPI=8
 HOMEPAGE=https://fasta.bioch.virginia.edu/fasta_www2/fasta_down.shtml
+INHERIT=flag-o-matic toolchain-funcs
 IUSE=debug cpu_flags_x86_sse2 test
 KEYWORDS=~amd64 ~ppc ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=fasta
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/wrpearson/fasta36/archive/refs/tags/v36.3.8h_04-May-2020.tar.gz -> fasta-36.3.8h.tar.gz
-_eclasses_=flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=741f3be1a17b816aabab39443236f37b
diff --git a/metadata/md5-cache/sci-biology/fasttree-2.1.11 b/metadata/md5-cache/sci-biology/fasttree-2.1.11
index 0c46b56fffa1..4c535ede7212 100644
--- a/metadata/md5-cache/sci-biology/fasttree-2.1.11
+++ b/metadata/md5-cache/sci-biology/fasttree-2.1.11
@@ -1,4 +1,4 @@
-BDEPEND=dev-util/ninja >=dev-util/cmake-3.20.5
+BDEPEND=>=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install prepare test unpack
 DESCRIPTION=Fast inference of approximately-maximum-likelihood phylogenetic trees
 EAPI=7
@@ -10,5 +10,5 @@ LICENSE=GPL-2
 REQUIRED_USE=?? ( double-precision cpu_flags_x86_sse3 )
 SLOT=0
 SRC_URI=http://www.microbesonline.org/fasttree/FastTree-2.1.11.c http://www.microbesonline.org/fasttree/FastTreeUPGMA.c -> FastTreeUPGMA-2.1.11.c http://www.microbesonline.org/fasttree/MOTreeComparison.tar.gz -> MOTreeComparison-2.1.11.tar.gz
-_eclasses_=cmake	90e2b29417d53718328f3a95227137a0	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
+_eclasses_=cmake	44afbf15c35884f7c840470f1cf05d0d	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
 _md5_=4a94b8db43f0aadb5ece67757ccbe635
diff --git a/metadata/md5-cache/sci-biology/fastx_toolkit-0.0.14 b/metadata/md5-cache/sci-biology/fastx_toolkit-0.0.14
deleted file mode 100644
index 85c33284ab20..000000000000
--- a/metadata/md5-cache/sci-biology/fastx_toolkit-0.0.14
+++ /dev/null
@@ -1,13 +0,0 @@
-DEFINED_PHASES=prepare
-DEPEND=sci-biology/libgtextutils virtual/pkgconfig sys-devel/gnuconfig >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.5:1.16 ) >=sys-devel/autoconf-2.71 >=sys-devel/libtool-2.4
-DESCRIPTION=Tools for Short Read FASTA/FASTQ file processing
-EAPI=6
-HOMEPAGE=http://hannonlab.cshl.edu/fastx_toolkit
-INHERIT=autotools
-KEYWORDS=~amd64 ~x86
-LICENSE=AGPL-3
-RDEPEND=dev-perl/PerlIO-gzip dev-perl/GDGraph sci-biology/libgtextutils:= sci-visualization/gnuplot
-SLOT=0
-SRC_URI=https://github.com/agordon/fastx_toolkit/releases/download/0.0.14/fastx_toolkit-0.0.14.tar.bz2
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
-_md5_=c3bb0edd6b01a31019cf5fd59e22122a
diff --git a/metadata/md5-cache/sci-biology/fastx_toolkit-0.0.14-r1 b/metadata/md5-cache/sci-biology/fastx_toolkit-0.0.14-r1
new file mode 100644
index 000000000000..df0e6a15f6e0
--- /dev/null
+++ b/metadata/md5-cache/sci-biology/fastx_toolkit-0.0.14-r1
@@ -0,0 +1,14 @@
+BDEPEND=virtual/pkgconfig sys-devel/gnuconfig >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.5:1.16 ) >=sys-devel/autoconf-2.71 >=sys-devel/libtool-2.4
+DEFINED_PHASES=prepare
+DEPEND=sci-biology/libgtextutils:=
+DESCRIPTION=Tools for Short Read FASTA/FASTQ file processing
+EAPI=8
+HOMEPAGE=http://hannonlab.cshl.edu/fastx_toolkit
+INHERIT=autotools
+KEYWORDS=~amd64 ~x86
+LICENSE=AGPL-3
+RDEPEND=sci-biology/libgtextutils:= dev-perl/PerlIO-gzip dev-perl/GDGraph sci-visualization/gnuplot
+SLOT=0
+SRC_URI=https://github.com/agordon/fastx_toolkit/releases/download/0.0.14/fastx_toolkit-0.0.14.tar.bz2
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
+_md5_=e0ed8e935eca944dc874fee38c4435ad
diff --git a/metadata/md5-cache/sci-biology/finchtv-1.3.1-r3 b/metadata/md5-cache/sci-biology/finchtv-1.3.1-r3
index 95de424d961e..61be013913ee 100644
--- a/metadata/md5-cache/sci-biology/finchtv-1.3.1-r3
+++ b/metadata/md5-cache/sci-biology/finchtv-1.3.1-r3
@@ -2,9 +2,10 @@ DEFINED_PHASES=install
 DESCRIPTION=Graphical viewer for chromatogram files
 EAPI=7
 HOMEPAGE=http://www.geospiza.com/finchtv/
+INHERIT=desktop
 KEYWORDS=amd64 x86 ~amd64-linux ~x86-linux
 LICENSE=finchtv
 SLOT=0
 SRC_URI=http://www.geospiza.com/finchtv/download/programs/linux/finchtv_1_3_1.tar.gz
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28
+_eclasses_=desktop	22952d8f27cac191d75529d4c38e6bfa
 _md5_=26ca9e399e95eecb3e72d2d0092706d3
diff --git a/metadata/md5-cache/sci-biology/foldingathome-7.6.13-r1 b/metadata/md5-cache/sci-biology/foldingathome-7.6.13-r1
index 9de2360f151d..9411204b7cbf 100644
--- a/metadata/md5-cache/sci-biology/foldingathome-7.6.13-r1
+++ b/metadata/md5-cache/sci-biology/foldingathome-7.6.13-r1
@@ -4,11 +4,12 @@ DEPEND=dev-util/patchelf
 DESCRIPTION=Folding@Home is a distributed computing project for protein folding
 EAPI=7
 HOMEPAGE=https://foldingathome.org/
+INHERIT=systemd
 KEYWORDS=~amd64
 LICENSE=FAH-EULA-2014 FAH-special-permission
 RDEPEND=acct-group/foldingathome acct-group/video acct-user/foldingathome app-arch/bzip2 || ( dev-libs/openssl-compat:1.0.0 =dev-libs/openssl-1.0*:* ) sys-devel/gcc sys-libs/glibc sys-libs/zlib
 RESTRICT=mirror bindist strip
 SLOT=0
 SRC_URI=https://download.foldingathome.org/releases/public/release/fahclient/centos-6.7-64bit/v7.6/fahclient_7.6.13-64bit-release.tar.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	systemd	2736b403a83f194b59b767f3b344c2c1	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	systemd	2736b403a83f194b59b767f3b344c2c1	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=f2ef46b617dbd53a6e9dbdd86ff70bf1
diff --git a/metadata/md5-cache/sci-biology/foldingathome-7.6.21 b/metadata/md5-cache/sci-biology/foldingathome-7.6.21
index a50b3bf30362..affdafdce866 100644
--- a/metadata/md5-cache/sci-biology/foldingathome-7.6.21
+++ b/metadata/md5-cache/sci-biology/foldingathome-7.6.21
@@ -4,11 +4,12 @@ DEPEND=dev-util/patchelf
 DESCRIPTION=Folding@Home is a distributed computing project for protein folding
 EAPI=8
 HOMEPAGE=https://foldingathome.org/
+INHERIT=systemd
 KEYWORDS=~amd64
 LICENSE=FAH-EULA-2014 FAH-special-permission
 RDEPEND=acct-group/foldingathome acct-group/video acct-user/foldingathome app-arch/bzip2 || ( dev-libs/openssl-compat:1.0.0 =dev-libs/openssl-1.0*:* ) sys-devel/gcc sys-libs/glibc sys-libs/zlib
 RESTRICT=mirror bindist strip
 SLOT=0
 SRC_URI=https://download.foldingathome.org/releases/public/release/fahclient/centos-6.7-64bit/v7.6/fahclient_7.6.21-64bit-release.tar.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	systemd	2736b403a83f194b59b767f3b344c2c1	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	systemd	2736b403a83f194b59b767f3b344c2c1	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=50de4ff6faf3b5ac3ed140d8e1653c23
diff --git a/metadata/md5-cache/sci-biology/glimmer-3.02b b/metadata/md5-cache/sci-biology/glimmer-3.02b
index 9f222feca53b..e5da458fa9a9 100644
--- a/metadata/md5-cache/sci-biology/glimmer-3.02b
+++ b/metadata/md5-cache/sci-biology/glimmer-3.02b
@@ -2,10 +2,11 @@ DEFINED_PHASES=compile install prepare
 DESCRIPTION=An HMM-based microbial gene finding system from TIGR
 EAPI=7
 HOMEPAGE=https://ccb.jhu.edu/software/glimmer/index.shtml
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=Artistic
 RDEPEND=app-shells/tcsh sci-biology/elph
 SLOT=0
 SRC_URI=https://ccb.jhu.edu/software/glimmer/glimmer302b.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=a7e8ed9c8bc30ed68f4fc465709c2e3d
diff --git a/metadata/md5-cache/sci-biology/glimmerhmm-3.0.1-r1 b/metadata/md5-cache/sci-biology/glimmerhmm-3.0.1-r1
index e1cb5b7d6b4d..af13ea5a9990 100644
--- a/metadata/md5-cache/sci-biology/glimmerhmm-3.0.1-r1
+++ b/metadata/md5-cache/sci-biology/glimmerhmm-3.0.1-r1
@@ -2,9 +2,10 @@ DEFINED_PHASES=compile configure install
 DESCRIPTION=A eukaryotic gene finding system from TIGR
 EAPI=7
 HOMEPAGE=http://www.cbcb.umd.edu/software/GlimmerHMM/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 x86
 LICENSE=Artistic
 SLOT=0
 SRC_URI=ftp://ftp.cbcb.umd.edu/pub/software/glimmerhmm/GlimmerHMM-3.0.1.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=9fc33629a982f35b93c18da772894fdd
diff --git a/metadata/md5-cache/sci-biology/iedera-1.05-r1 b/metadata/md5-cache/sci-biology/iedera-1.05-r1
index 2f685df34b73..17964bdb426c 100644
--- a/metadata/md5-cache/sci-biology/iedera-1.05-r1
+++ b/metadata/md5-cache/sci-biology/iedera-1.05-r1
@@ -8,5 +8,5 @@ KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=http://bioinfo.lifl.fr/yass/files/iedera-1.05.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=ce77e1e27bd52fed2fd2af52744d6288
diff --git a/metadata/md5-cache/sci-biology/infernal-1.0.2-r1 b/metadata/md5-cache/sci-biology/infernal-1.0.2-r1
index 12933fcab50e..7243c366bd6d 100644
--- a/metadata/md5-cache/sci-biology/infernal-1.0.2-r1
+++ b/metadata/md5-cache/sci-biology/infernal-1.0.2-r1
@@ -3,11 +3,12 @@ DEPEND=mpi? ( virtual/mpi )
 DESCRIPTION=Inference of RNA alignments
 EAPI=7
 HOMEPAGE=http://infernal.janelia.org/
+INHERIT=toolchain-funcs
 IUSE=mpi
 KEYWORDS=amd64 x86
 LICENSE=GPL-3
 RDEPEND=mpi? ( virtual/mpi )
 SLOT=0
 SRC_URI=ftp://selab.janelia.org/pub/software/infernal/infernal-1.0.2.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=a3b1f788e8f5b38e41b3a9e38f91fe88
diff --git a/metadata/md5-cache/sci-biology/kalign-2.03-r2 b/metadata/md5-cache/sci-biology/kalign-2.03-r2
index 5cba14569012..00c2b282957b 100644
--- a/metadata/md5-cache/sci-biology/kalign-2.03-r2
+++ b/metadata/md5-cache/sci-biology/kalign-2.03-r2
@@ -2,9 +2,10 @@ DEFINED_PHASES=compile install prepare
 DESCRIPTION=Global and progressive multiple sequence alignment
 EAPI=6
 HOMEPAGE=http://msa.cgb.ki.se/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=mirror://debian/pool/main/k/kalign/kalign_2.03.orig.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=175d26382226c7bed2b44be485b01d01
diff --git a/metadata/md5-cache/sci-biology/kallisto-0.46.2 b/metadata/md5-cache/sci-biology/kallisto-0.46.2
index 36d918938ae6..895da23800ba 100644
--- a/metadata/md5-cache/sci-biology/kallisto-0.46.2
+++ b/metadata/md5-cache/sci-biology/kallisto-0.46.2
@@ -1,4 +1,4 @@
-BDEPEND=virtual/pkgconfig dev-util/ninja >=dev-util/cmake-3.20.5
+BDEPEND=virtual/pkgconfig >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install prepare test
 DEPEND=sci-libs/htslib:= sys-libs/zlib:= hdf5? ( sci-libs/hdf5:= ) test? ( dev-cpp/catch:0 sci-libs/hdf5 )
 DESCRIPTION=Near-optimal RNA-Seq quantification
@@ -12,5 +12,5 @@ RDEPEND=sci-libs/htslib:= sys-libs/zlib:= hdf5? ( sci-libs/hdf5:= )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/pachterlab/kallisto/archive/v0.46.2.tar.gz -> kallisto-0.46.2.tar.gz
-_eclasses_=cmake	90e2b29417d53718328f3a95227137a0	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
+_eclasses_=cmake	44afbf15c35884f7c840470f1cf05d0d	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
 _md5_=1b739cad0275e6dc5a320723611b78e9
diff --git a/metadata/md5-cache/sci-biology/lagan-2.0-r4 b/metadata/md5-cache/sci-biology/lagan-2.0-r4
index d4f6396b6c3b..a67e7ee16bc6 100644
--- a/metadata/md5-cache/sci-biology/lagan-2.0-r4
+++ b/metadata/md5-cache/sci-biology/lagan-2.0-r4
@@ -2,10 +2,11 @@ DEFINED_PHASES=configure install prepare
 DESCRIPTION=The LAGAN suite of tools for whole-genome multiple alignment of genomic DNA
 EAPI=7
 HOMEPAGE=http://lagan.stanford.edu/lagan_web/index.shtml
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 RDEPEND=dev-lang/perl
 SLOT=0
 SRC_URI=http://lagan.stanford.edu/lagan_web/lagan20.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=c4b4e347541c85d423cac28e03a104d4
diff --git a/metadata/md5-cache/sci-biology/libgtextutils-0.6.1 b/metadata/md5-cache/sci-biology/libgtextutils-0.6.1
deleted file mode 100644
index 5331c57d89ed..000000000000
--- a/metadata/md5-cache/sci-biology/libgtextutils-0.6.1
+++ /dev/null
@@ -1,12 +0,0 @@
-DEFINED_PHASES=configure install prepare
-DEPEND=sys-devel/gnuconfig >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.5:1.16 ) >=sys-devel/autoconf-2.71 >=sys-devel/libtool-2.4
-DESCRIPTION=Gordon Text utils Library
-EAPI=6
-HOMEPAGE=http://hannonlab.cshl.edu/fastx_toolkit/
-INHERIT=autotools
-KEYWORDS=~amd64 ~x86
-LICENSE=AGPL-3
-SLOT=0/0
-SRC_URI=http://hannonlab.cshl.edu/fastx_toolkit/libgtextutils-0.6.1.tar.bz2
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
-_md5_=867c9b9e4eee26ad2a76ff6ff0594f52
diff --git a/metadata/md5-cache/sci-biology/libgtextutils-0.6.1-r1 b/metadata/md5-cache/sci-biology/libgtextutils-0.6.1-r1
new file mode 100644
index 000000000000..4eb11089d93a
--- /dev/null
+++ b/metadata/md5-cache/sci-biology/libgtextutils-0.6.1-r1
@@ -0,0 +1,12 @@
+BDEPEND=sys-devel/gnuconfig >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.5:1.16 ) >=sys-devel/autoconf-2.71 >=sys-devel/libtool-2.4
+DEFINED_PHASES=install prepare
+DESCRIPTION=Gordon Text utils Library
+EAPI=8
+HOMEPAGE=http://hannonlab.cshl.edu/fastx_toolkit/
+INHERIT=autotools
+KEYWORDS=~amd64 ~x86
+LICENSE=AGPL-3
+SLOT=0/0
+SRC_URI=http://hannonlab.cshl.edu/fastx_toolkit/libgtextutils-0.6.1.tar.bz2
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
+_md5_=bf69c3370f31858d1ff072c30305ca99
diff --git a/metadata/md5-cache/sci-biology/mafft-7.305 b/metadata/md5-cache/sci-biology/mafft-7.305
deleted file mode 100644
index 31193fbffb29..000000000000
--- a/metadata/md5-cache/sci-biology/mafft-7.305
+++ /dev/null
@@ -1,12 +0,0 @@
-DEFINED_PHASES=compile install prepare test
-DESCRIPTION=Multiple sequence alignments using a variety of algorithms
-EAPI=6
-HOMEPAGE=https://mafft.cbrc.jp/alignment/software/index.html
-INHERIT=flag-o-matic toolchain-funcs
-IUSE=threads
-KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
-LICENSE=BSD
-SLOT=0
-SRC_URI=https://mafft.cbrc.jp/alignment/software/mafft-7.305-without-extensions-src.tgz
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
-_md5_=0f3bc4071e292477254a6b10ab15b328
diff --git a/metadata/md5-cache/sci-biology/mafft-7.490 b/metadata/md5-cache/sci-biology/mafft-7.490
new file mode 100644
index 000000000000..695dddcc98d6
--- /dev/null
+++ b/metadata/md5-cache/sci-biology/mafft-7.490
@@ -0,0 +1,11 @@
+DEFINED_PHASES=compile configure install prepare test
+DESCRIPTION=Multiple sequence alignments using a variety of algorithms
+EAPI=8
+HOMEPAGE=https://mafft.cbrc.jp/alignment/software/index.html
+INHERIT=flag-o-matic toolchain-funcs
+KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
+LICENSE=BSD
+SLOT=0
+SRC_URI=https://mafft.cbrc.jp/alignment/software/mafft-7.490-without-extensions-src.tgz
+_eclasses_=flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
+_md5_=04971be2bc4044a9c136d12a7e51b23d
diff --git a/metadata/md5-cache/sci-biology/maq-0.7.1-r2 b/metadata/md5-cache/sci-biology/maq-0.7.1-r2
index 33a7ed2f89ae..c17f54cc216a 100644
--- a/metadata/md5-cache/sci-biology/maq-0.7.1-r2
+++ b/metadata/md5-cache/sci-biology/maq-0.7.1-r2
@@ -9,5 +9,5 @@ LICENSE=GPL-3
 RDEPEND=sys-libs/zlib
 SLOT=0
 SRC_URI=mirror://sourceforge/maq/maq-0.7.1.tar.bz2 mirror://sourceforge/maq/calib-36.dat.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=39ffb0025210075a8d7d7f6f81f8da56
diff --git a/metadata/md5-cache/sci-biology/maqview-0.2.5-r3 b/metadata/md5-cache/sci-biology/maqview-0.2.5-r3
index 20b8c654dd41..a60b0e13e116 100644
--- a/metadata/md5-cache/sci-biology/maqview-0.2.5-r3
+++ b/metadata/md5-cache/sci-biology/maqview-0.2.5-r3
@@ -9,5 +9,5 @@ LICENSE=GPL-3
 RDEPEND=media-libs/freeglut sys-libs/zlib sci-biology/maq
 SLOT=0
 SRC_URI=mirror://sourceforge/maq/maqview-0.2.5.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=dee50558d10e75ff9e96f4c3f177c55f
diff --git a/metadata/md5-cache/sci-biology/mcl-14.137 b/metadata/md5-cache/sci-biology/mcl-14.137
index bb7e6ba6bf54..c797da2af65c 100644
--- a/metadata/md5-cache/sci-biology/mcl-14.137
+++ b/metadata/md5-cache/sci-biology/mcl-14.137
@@ -3,10 +3,11 @@ DEFINED_PHASES=configure prepare
 DESCRIPTION=A Markov Cluster Algorithm implementation
 EAPI=7
 HOMEPAGE=http://micans.org/mcl/
+INHERIT=autotools
 IUSE=+blast
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=http://micans.org/mcl/src/mcl-14-137.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=9779366f51f2fea08274072a9a019159
diff --git a/metadata/md5-cache/sci-biology/mosaik-2.2.30 b/metadata/md5-cache/sci-biology/mosaik-2.2.30
index 64cbfd699276..4f23e5c6948e 100644
--- a/metadata/md5-cache/sci-biology/mosaik-2.2.30
+++ b/metadata/md5-cache/sci-biology/mosaik-2.2.30
@@ -2,9 +2,10 @@ DEFINED_PHASES=compile configure install unpack
 DESCRIPTION=A reference-guided aligner for next-generation sequencing technologies
 EAPI=7
 HOMEPAGE=https://github.com/wanpinglee/MOSAIK
+INHERIT=flag-o-matic toolchain-funcs vcs-snapshot
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=https://github.com/wanpinglee/MOSAIK/archive/5c25216d3522d6a33e53875cd76a6d65001e4e67.tar.gz -> mosaik-2.2.30.tar.gz
-_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-snapshot	19dc666868420457132a7514d4621476	wrapper	4a1902f969e5718126434fc35f3a0d9c
-_md5_=986f3a07cbf0dd1e4d247e0f7a43eb56
+_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-snapshot	19dc666868420457132a7514d4621476	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_md5_=b275a0e18dbe85d2a2e24cebc796c134
diff --git a/metadata/md5-cache/sci-biology/mothur-1.27.0-r1 b/metadata/md5-cache/sci-biology/mothur-1.27.0-r1
index 1d49d9fe90f4..2561ab88f887 100644
--- a/metadata/md5-cache/sci-biology/mothur-1.27.0-r1
+++ b/metadata/md5-cache/sci-biology/mothur-1.27.0-r1
@@ -4,11 +4,12 @@ DEPEND=sci-biology/uchime mpi? ( virtual/mpi ) virtual/fortran
 DESCRIPTION=A suite of algorithms for ecological bioinformatics
 EAPI=7
 HOMEPAGE=https://www.mothur.org/
+INHERIT=flag-o-matic fortran-2 toolchain-funcs
 IUSE=mpi +readline
 KEYWORDS=amd64 x86
 LICENSE=GPL-3
 RDEPEND=sci-biology/uchime mpi? ( virtual/mpi ) virtual/fortran
 SLOT=0
 SRC_URI=https://www.mothur.org/w/images/c/cb/Mothur.1.27.0.zip -> mothur-1.27.0.zip
-_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	fortran-2	72d28c6872beb1e7cb99684b0ae4715d	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	fortran-2	72d28c6872beb1e7cb99684b0ae4715d	multilib	4fbbbc98f236f1b43acd99476bc3cd85	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=2a931ea6d0536a0cb3441d235f5d2d6b
diff --git a/metadata/md5-cache/sci-biology/mrbayes-3.1.2-r2 b/metadata/md5-cache/sci-biology/mrbayes-3.1.2-r2
index f398cccd3eb9..ee556f278f9e 100644
--- a/metadata/md5-cache/sci-biology/mrbayes-3.1.2-r2
+++ b/metadata/md5-cache/sci-biology/mrbayes-3.1.2-r2
@@ -3,11 +3,12 @@ DEPEND=sys-libs/ncurses:= mpi? ( virtual/mpi ) readline? ( sys-libs/readline:= )
 DESCRIPTION=Bayesian Inference of Phylogeny
 EAPI=8
 HOMEPAGE=http://mrbayes.csit.fsu.edu/
+INHERIT=toolchain-funcs
 IUSE=debug mpi readline
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~ppc-macos ~sparc-solaris
 LICENSE=GPL-2
 RDEPEND=sys-libs/ncurses:= mpi? ( virtual/mpi ) readline? ( sys-libs/readline:= )
 SLOT=0
 SRC_URI=mirror://sourceforge/mrbayes/mrbayes-3.1.2.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=5905565f0c29b3c7b9098cfb7a50e760
diff --git a/metadata/md5-cache/sci-biology/mummer-3.23 b/metadata/md5-cache/sci-biology/mummer-3.23
index 3e7a9792fee2..d59cbf202c98 100644
--- a/metadata/md5-cache/sci-biology/mummer-3.23
+++ b/metadata/md5-cache/sci-biology/mummer-3.23
@@ -9,5 +9,5 @@ LICENSE=Artistic
 RDEPEND=app-shells/tcsh dev-lang/perl
 SLOT=0
 SRC_URI=mirror://sourceforge/mummer/MUMmer3.23.tar.gz
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=c256f298b416306c1be7005e7877f7b9
diff --git a/metadata/md5-cache/sci-biology/muscle-3.8.31 b/metadata/md5-cache/sci-biology/muscle-3.8.31
index 5786ad01aa84..322f200b500e 100644
--- a/metadata/md5-cache/sci-biology/muscle-3.8.31
+++ b/metadata/md5-cache/sci-biology/muscle-3.8.31
@@ -2,10 +2,11 @@ DEFINED_PHASES=configure install
 DESCRIPTION=Multiple sequence comparison by log-expectation
 EAPI=7
 HOMEPAGE=http://www.drive5.com/muscle/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 ~ppc x86
 LICENSE=public-domain
 RDEPEND=!sci-libs/libmuscle
 SLOT=0
 SRC_URI=http://www.drive5.com/muscle/downloads3.8.31/muscle3.8.31_src.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=70730a85bf27816f07c7b7498e5adc91
diff --git a/metadata/md5-cache/sci-biology/newick-utils-1.6-r1 b/metadata/md5-cache/sci-biology/newick-utils-1.6-r1
index ece92e43759f..87d1d473c1ac 100644
--- a/metadata/md5-cache/sci-biology/newick-utils-1.6-r1
+++ b/metadata/md5-cache/sci-biology/newick-utils-1.6-r1
@@ -4,11 +4,12 @@ DEPEND=xml? ( dev-libs/libxml2 )
 DESCRIPTION=Tools for processing phylogenetic trees
 EAPI=7
 HOMEPAGE=http://cegg.unige.ch/newick_utils
+INHERIT=autotools
 IUSE=xml
 KEYWORDS=~amd64 ~x86
 LICENSE=BSD
 RDEPEND=xml? ( dev-libs/libxml2 ) !dev-games/libnw
 SLOT=0
 SRC_URI=http://cegg.unige.ch/pub/newick-utils-1.6.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=fac40fe86b457a75883a5eb465ce18d8
diff --git a/metadata/md5-cache/sci-biology/pals-1.0-r1 b/metadata/md5-cache/sci-biology/pals-1.0-r1
index 157638f8ed9f..273273cafd60 100644
--- a/metadata/md5-cache/sci-biology/pals-1.0-r1
+++ b/metadata/md5-cache/sci-biology/pals-1.0-r1
@@ -2,9 +2,10 @@ DEFINED_PHASES=configure install
 DESCRIPTION=Pairwise Aligner for Long Sequences
 EAPI=6
 HOMEPAGE=http://www.drive5.com/pals/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 x86
 LICENSE=public-domain
 SLOT=0
 SRC_URI=http://www.drive5.com/pals/pals_source.tar.gz -> pals-1.0.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=b0df20d47905df6a290c5fe2f79fd48b
diff --git a/metadata/md5-cache/sci-biology/paml-4.9j b/metadata/md5-cache/sci-biology/paml-4.9j
index 533841ff6073..8dc4fa91e6d5 100644
--- a/metadata/md5-cache/sci-biology/paml-4.9j
+++ b/metadata/md5-cache/sci-biology/paml-4.9j
@@ -2,9 +2,10 @@ DEFINED_PHASES=compile configure install
 DESCRIPTION=Phylogenetic Analysis by Maximum Likelihood
 EAPI=7
 HOMEPAGE=http://abacus.gene.ucl.ac.uk/software/paml.html
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=free-noncomm
 SLOT=0
 SRC_URI=http://abacus.gene.ucl.ac.uk/software/paml4.9j.tgz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=236ce838eff8e04f8059e18110b3ff38
diff --git a/metadata/md5-cache/sci-biology/phrap-1.080812-r2 b/metadata/md5-cache/sci-biology/phrap-1.080812-r2
index 43b4d6b12397..6246c3cf8f92 100644
--- a/metadata/md5-cache/sci-biology/phrap-1.080812-r2
+++ b/metadata/md5-cache/sci-biology/phrap-1.080812-r2
@@ -2,11 +2,12 @@ DEFINED_PHASES=compile install nofetch
 DESCRIPTION=Shotgun assembly and alignment utilities
 EAPI=6
 HOMEPAGE=http://www.phrap.org/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=phrap
 RDEPEND=dev-lang/perl dev-perl/Tk
 RESTRICT=fetch
 SLOT=0
 SRC_URI=phrap-1.080812-distrib.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=8f5aa73e6a49ffbd5804d4ddea05b2b8
diff --git a/metadata/md5-cache/sci-biology/phred-071220-r1 b/metadata/md5-cache/sci-biology/phred-071220-r1
index bcd194a29355..5ecf5b9e49e8 100644
--- a/metadata/md5-cache/sci-biology/phred-071220-r1
+++ b/metadata/md5-cache/sci-biology/phred-071220-r1
@@ -2,10 +2,11 @@ DEFINED_PHASES=compile install nofetch
 DESCRIPTION=A base caller for Sanger DNA sequencing
 EAPI=6
 HOMEPAGE=http://phrap.org/phredphrapconsed.html
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=phrap
 RESTRICT=fetch
 SLOT=0
 SRC_URI=phred-dist-071220.b-acd.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=6cb07f602eee34da61fd893818f30936
diff --git a/metadata/md5-cache/sci-biology/phylip-3.698 b/metadata/md5-cache/sci-biology/phylip-3.698
index 52d5df364c4d..cc6a95422ee2 100644
--- a/metadata/md5-cache/sci-biology/phylip-3.698
+++ b/metadata/md5-cache/sci-biology/phylip-3.698
@@ -4,10 +4,11 @@ DEPEND=x11-libs/libXaw !dev-lang/elixir x11-base/xorg-proto
 DESCRIPTION=The PHYLogeny Inference Package
 EAPI=7
 HOMEPAGE=http://evolution.genetics.washington.edu/phylip.html
+INHERIT=flag-o-matic toolchain-funcs
 KEYWORDS=~amd64 ~ppc ~x86 ~amd64-linux ~x86-linux ~ppc-macos
 LICENSE=BSD-2
 RDEPEND=x11-libs/libXaw !dev-lang/elixir
 SLOT=0
 SRC_URI=http://evolution.gs.washington.edu/phylip/download/phylip-3.698.zip
-_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=b3a777c086ea4a6cd489efcb5bde7b66
diff --git a/metadata/md5-cache/sci-biology/phyml-2.4.5-r3 b/metadata/md5-cache/sci-biology/phyml-2.4.5-r3
index b23078a3db07..adea41dcfeca 100644
--- a/metadata/md5-cache/sci-biology/phyml-2.4.5-r3
+++ b/metadata/md5-cache/sci-biology/phyml-2.4.5-r3
@@ -2,9 +2,10 @@ DEFINED_PHASES=install prepare
 DESCRIPTION=Estimation of large phylogenies by maximum likelihood
 EAPI=6
 HOMEPAGE=http://atgc.lirmm.fr/phyml/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 ~ppc x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=http://www.lirmm.fr/~guindon/phyml_v2.4.5.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=8909f510fa1072825fa60fbc8a72920e
diff --git a/metadata/md5-cache/sci-biology/piler-1.0-r1 b/metadata/md5-cache/sci-biology/piler-1.0-r1
index 967645c3849c..37cefb4af481 100644
--- a/metadata/md5-cache/sci-biology/piler-1.0-r1
+++ b/metadata/md5-cache/sci-biology/piler-1.0-r1
@@ -2,10 +2,11 @@ DEFINED_PHASES=configure install
 DESCRIPTION=Analysis of repetitive DNA found in genome sequences
 EAPI=6
 HOMEPAGE=http://www.drive5.com/piler/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 x86
 LICENSE=public-domain
 RDEPEND=|| ( sci-biology/muscle sci-libs/libmuscle ) sci-biology/pals
 SLOT=0
 SRC_URI=http://www.drive5.com/piler/piler_source.tar.gz -> piler-1.0.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=7b5a6d618aac08240cf165a04509c319
diff --git a/metadata/md5-cache/sci-biology/pilercr-1.0-r1 b/metadata/md5-cache/sci-biology/pilercr-1.0-r1
index b9bfe498dc53..ab7fc7d1e02d 100644
--- a/metadata/md5-cache/sci-biology/pilercr-1.0-r1
+++ b/metadata/md5-cache/sci-biology/pilercr-1.0-r1
@@ -2,9 +2,10 @@ DEFINED_PHASES=configure install
 DESCRIPTION=Analysis of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs)
 EAPI=6
 HOMEPAGE=http://www.drive5.com/pilercr/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 x86
 LICENSE=public-domain
 SLOT=0
 SRC_URI=http://www.drive5.com/pilercr/pilercr1.06.tar.gz -> pilercr-1.0.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=d9f7901d3776c424cfb93782cc6ddafa
diff --git a/metadata/md5-cache/sci-biology/plink-1.90_pre140514 b/metadata/md5-cache/sci-biology/plink-1.90_pre140514
index 9600491b5af5..74341dca4cb6 100644
--- a/metadata/md5-cache/sci-biology/plink-1.90_pre140514
+++ b/metadata/md5-cache/sci-biology/plink-1.90_pre140514
@@ -4,10 +4,11 @@ DEPEND=sys-libs/zlib virtual/cblas virtual/lapack
 DESCRIPTION=Whole genome association analysis toolset
 EAPI=8
 HOMEPAGE=http://pngu.mgh.harvard.edu/~purcell/plink/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 RDEPEND=sys-libs/zlib virtual/cblas virtual/lapack
 SLOT=0
 SRC_URI=http://pngu.mgh.harvard.edu/~purcell/static/bin/plink140514/plink_src.zip -> plink-1.90_pre140514.zip
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=419587bbc06b4b3717534c9c0148238b
diff --git a/metadata/md5-cache/sci-biology/poa-2-r1 b/metadata/md5-cache/sci-biology/poa-2-r1
index e68887c13498..36af2d13a888 100644
--- a/metadata/md5-cache/sci-biology/poa-2-r1
+++ b/metadata/md5-cache/sci-biology/poa-2-r1
@@ -2,9 +2,10 @@ DEFINED_PHASES=compile configure install postinst
 DESCRIPTION=Fast multiple sequence alignments using partial-order graphs
 EAPI=7
 HOMEPAGE=http://bioinfo.mbi.ucla.edu/poa/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=mirror://sourceforge/poamsa/poaV2.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=d7bb9c94a05320cd21ff72a8beb56406
diff --git a/metadata/md5-cache/sci-biology/prank-140603 b/metadata/md5-cache/sci-biology/prank-140603
index ca924734e71f..466a5226a02e 100644
--- a/metadata/md5-cache/sci-biology/prank-140603
+++ b/metadata/md5-cache/sci-biology/prank-140603
@@ -2,9 +2,10 @@ DEFINED_PHASES=compile install prepare
 DESCRIPTION=Probabilistic Alignment Kit
 EAPI=6
 HOMEPAGE=http://wasabiapp.org/software/prank/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-3
 SLOT=0
 SRC_URI=http://wasabiapp.org/download/prank/prank.source.140603.tgz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=17023476000980284365a9c0ed04a6f0
diff --git a/metadata/md5-cache/sci-biology/primer3-2.3.7 b/metadata/md5-cache/sci-biology/primer3-2.3.7-r1
index 2273b4b32c0a..913fd7cdb093 100644
--- a/metadata/md5-cache/sci-biology/primer3-2.3.7
+++ b/metadata/md5-cache/sci-biology/primer3-2.3.7-r1
@@ -1,11 +1,12 @@
+BDEPEND=dev-lang/perl
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=dev-lang/perl
 DESCRIPTION=Primer Design for PCR reactions
-EAPI=6
+EAPI=8
 HOMEPAGE=http://primer3.sourceforge.net/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~ppc ~ppc64 ~sparc ~x86 ~amd64-linux ~x86-linux ~ppc-macos ~sparc-solaris
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=mirror://sourceforge/project/primer3/primer3/2.3.7/primer3-2.3.7.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
-_md5_=e79ee4774138e651c83467c2b2cb2926
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
+_md5_=f0e187a7011db2129b8874b8bf3e3496
diff --git a/metadata/md5-cache/sci-biology/prints-39.0-r1 b/metadata/md5-cache/sci-biology/prints-39.0-r2
index 31cee51db19f..23a0ba457da1 100644
--- a/metadata/md5-cache/sci-biology/prints-39.0-r1
+++ b/metadata/md5-cache/sci-biology/prints-39.0-r2
@@ -1,7 +1,7 @@
+BDEPEND=emboss? ( sci-biology/emboss )
 DEFINED_PHASES=compile install
-DEPEND=emboss? ( sci-biology/emboss )
 DESCRIPTION=A protein motif fingerprint database
-EAPI=6
+EAPI=8
 HOMEPAGE=http://www.bioinf.man.ac.uk/dbbrowser/PRINTS/
 IUSE=emboss minimal
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
@@ -9,4 +9,4 @@ LICENSE=public-domain
 RDEPEND=emboss? ( sci-biology/emboss )
 SLOT=0
 SRC_URI=mirror://gentoo/prints-39.0.tar.bz2
-_md5_=03843bbc5bed197d8df7a7bbc970230a
+_md5_=79d0547e585a924037242281d1a5469b
diff --git a/metadata/md5-cache/sci-biology/probcons-1.12-r1 b/metadata/md5-cache/sci-biology/probcons-1.12-r1
index 408ab32abf07..1e35053e9d95 100644
--- a/metadata/md5-cache/sci-biology/probcons-1.12-r1
+++ b/metadata/md5-cache/sci-biology/probcons-1.12-r1
@@ -2,10 +2,11 @@ DEFINED_PHASES=compile install postinst
 DESCRIPTION=Probabilistic Consistency-based Multiple Alignment of Amino Acid Sequences
 EAPI=7
 HOMEPAGE=http://probcons.stanford.edu/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 x86 ~amd64-linux ~x86-linux
 LICENSE=public-domain
 RDEPEND=!sci-geosciences/gmt sci-visualization/gnuplot
 SLOT=0
 SRC_URI=http://probcons.stanford.edu/probcons_v1_12.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=0f60285a7f7c2929aed4404425c3fc40
diff --git a/metadata/md5-cache/sci-biology/prodigal-2.6.3 b/metadata/md5-cache/sci-biology/prodigal-2.6.3
index 6adc2ba71741..c0ce255add3d 100644
--- a/metadata/md5-cache/sci-biology/prodigal-2.6.3
+++ b/metadata/md5-cache/sci-biology/prodigal-2.6.3
@@ -2,9 +2,10 @@ DEFINED_PHASES=configure
 DESCRIPTION=Prokaryotic Dynamic Programming Genefinding Algorithm
 EAPI=6
 HOMEPAGE=http://prodigal.ornl.gov/
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64
 LICENSE=GPL-3
 SLOT=0
 SRC_URI=https://github.com/hyattpd/Prodigal/archive/v2.6.3.tar.gz -> prodigal-2.6.3.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=9cea3bcc55e864076d7e4b542f657f96
diff --git a/metadata/md5-cache/sci-biology/prosite-2017.02 b/metadata/md5-cache/sci-biology/prosite-2017.02-r1
index ccabbc4a37bb..cef8da6a920b 100644
--- a/metadata/md5-cache/sci-biology/prosite-2017.02
+++ b/metadata/md5-cache/sci-biology/prosite-2017.02-r1
@@ -1,7 +1,7 @@
+BDEPEND=emboss? ( sci-biology/emboss )
 DEFINED_PHASES=compile install
-DEPEND=emboss? ( sci-biology/emboss )
 DESCRIPTION=A protein families and domains database
-EAPI=6
+EAPI=8
 HOMEPAGE=https://prosite.expasy.org/
 IUSE=emboss minimal
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
@@ -9,4 +9,4 @@ LICENSE=swiss-prot
 RDEPEND=emboss? ( sci-biology/emboss )
 SLOT=0
 SRC_URI=ftp://ftp.expasy.org/databases/prosite/old_releases/prosite2017_02.tar.bz2
-_md5_=e37bd9f81e9458715d22a6138fb2029a
+_md5_=05ff9ed4f5365bf3491e146b89f1aa5a
diff --git a/metadata/md5-cache/sci-biology/pysam-0.17.0 b/metadata/md5-cache/sci-biology/pysam-0.17.0
deleted file mode 100644
index 748745c88b61..000000000000
--- a/metadata/md5-cache/sci-biology/pysam-0.17.0
+++ /dev/null
@@ -1,17 +0,0 @@
-BDEPEND=test? ( =sci-biology/bcftools-1.13* =sci-biology/samtools-1.13* ) test? ( =sci-libs/htslib-1.13*:= >=dev-python/pytest-7.0.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 ) >=dev-python/setuptools-42.0.2[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
-DEFINED_PHASES=compile configure install prepare test
-DEPEND==sci-libs/htslib-1.13*:= dev-python/cython[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/setuptools[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
-DESCRIPTION=Python interface for the SAM/BAM sequence alignment and mapping format
-EAPI=8
-HOMEPAGE=https://github.com/pysam-developers/pysam https://pypi.org/project/pysam/
-INHERIT=distutils-r1
-IUSE=test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
-KEYWORDS=~amd64 ~x86
-LICENSE=MIT
-RDEPEND==sci-libs/htslib-1.13*:= python_targets_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 )
-REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
-RESTRICT=!test? ( test )
-SLOT=0
-SRC_URI=https://github.com/pysam-developers/pysam/archive/v0.17.0.tar.gz -> pysam-0.17.0.tar.gz
-_eclasses_=distutils-r1	3b871cf4724e3abc9b4ff059289f0d45	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-r1	8638751691200e941f26fe0ac3aef1d1	python-utils-r1	5dc84801daa87406aafaf535cb947a64	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
-_md5_=5afaf93aeaee2506b60aa22aac9b3a2c
diff --git a/metadata/md5-cache/sci-biology/pysam-0.19.1 b/metadata/md5-cache/sci-biology/pysam-0.19.1
new file mode 100644
index 000000000000..36eb5745fbdf
--- /dev/null
+++ b/metadata/md5-cache/sci-biology/pysam-0.19.1
@@ -0,0 +1,17 @@
+BDEPEND=test? ( =sci-biology/bcftools-1.15.1* =sci-biology/samtools-1.15.1* ) test? ( =sci-libs/htslib-1.15.1*:= >=dev-python/pytest-7.0.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.0_beta1-r1:3.11 ) >=dev-python/setuptools-42.0.2[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?]
+DEFINED_PHASES=compile configure install prepare test
+DEPEND==sci-libs/htslib-1.15.1*:= dev-python/cython[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] dev-python/setuptools[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?]
+DESCRIPTION=Python interface for the SAM/BAM sequence alignment and mapping format
+EAPI=8
+HOMEPAGE=https://github.com/pysam-developers/pysam https://pypi.org/project/pysam/
+INHERIT=distutils-r1
+IUSE=test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 python_targets_python3_11
+KEYWORDS=~amd64 ~x86
+LICENSE=MIT
+RDEPEND==sci-libs/htslib-1.15.1*:= python_targets_python3_8? ( >=dev-lang/python-3.8.12_p1-r1:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.9-r1:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.0_p1-r1:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.0_beta1-r1:3.11 )
+REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 python_targets_python3_11 )
+RESTRICT=!test? ( test )
+SLOT=0
+SRC_URI=https://github.com/pysam-developers/pysam/archive/v0.19.1.tar.gz -> pysam-0.19.1.gh.tar.gz
+_eclasses_=distutils-r1	10a93585889c3ca7651cbcd2ee831e47	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-r1	e2883e4f04f0503cdf7f2954e2bf5e15	python-utils-r1	648fe6a039e87233d7f48da72cadb76f	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
+_md5_=baed35c86cd8709cd139815786cd17ac
diff --git a/metadata/md5-cache/sci-biology/qrna-2.0.3c-r3 b/metadata/md5-cache/sci-biology/qrna-2.0.3c-r3
index c787cb0757f5..bbfa89a1231a 100644
--- a/metadata/md5-cache/sci-biology/qrna-2.0.3c-r3
+++ b/metadata/md5-cache/sci-biology/qrna-2.0.3c-r3
@@ -3,10 +3,11 @@ DEPEND=dev-lang/perl sci-biology/hmmer:2
 DESCRIPTION=Prototype ncRNA genefinder
 EAPI=7
 HOMEPAGE=http://selab.janelia.org/software.html
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 RDEPEND=dev-lang/perl sci-biology/hmmer:2
 SLOT=0
 SRC_URI=mirror://gentoo/qrna-2.0.3c.tar.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=fdc52d5355060d858ec78d793dc26d81
diff --git a/metadata/md5-cache/sci-biology/raxml-7.2.6 b/metadata/md5-cache/sci-biology/raxml-7.2.6
index a16a9fad80aa..2a45ddeeacb8 100644
--- a/metadata/md5-cache/sci-biology/raxml-7.2.6
+++ b/metadata/md5-cache/sci-biology/raxml-7.2.6
@@ -2,11 +2,12 @@ DEFINED_PHASES=compile configure install
 DESCRIPTION=Sequential, Parallel & Distributed Inference of Large Phylogenetic Trees
 EAPI=7
 HOMEPAGE=http://wwwkramer.in.tum.de/exelixis/software.html
+INHERIT=flag-o-matic toolchain-funcs
 IUSE=cpu_flags_x86_sse3 +threads
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 REQUIRED_USE=cpu_flags_x86_sse3
 SLOT=0
 SRC_URI=http://wwwkramer.in.tum.de/exelixis/software/RAxML-7.2.6.tar.bz2
-_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=14b77d8b019468c10a65f1358be0d8ae
diff --git a/metadata/md5-cache/sci-biology/rebase-1901 b/metadata/md5-cache/sci-biology/rebase-1901-r1
index b5a635750eee..592b54d4bf16 100644
--- a/metadata/md5-cache/sci-biology/rebase-1901
+++ b/metadata/md5-cache/sci-biology/rebase-1901-r1
@@ -1,13 +1,12 @@
+BDEPEND=emboss? ( sci-biology/emboss )
 DEFINED_PHASES=compile install
-DEPEND=emboss? ( >=sci-biology/emboss-5.0.0 )
 DESCRIPTION=A restriction enzyme database
-EAPI=6
+EAPI=8
 HOMEPAGE=http://rebase.neb.com
 IUSE=emboss minimal
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~ppc-macos ~sparc-solaris ~x86-solaris
 LICENSE=public-domain
-RDEPEND=emboss? ( >=sci-biology/emboss-5.0.0 )
 RESTRICT=binchecks strip
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/rebase-1901.tar.xz
-_md5_=af6eb0bdb9d763276057136d501fc836
+_md5_=0d6e32883752d19d6e086fd1a9f809ac
diff --git a/metadata/md5-cache/sci-biology/recon-1.08 b/metadata/md5-cache/sci-biology/recon-1.08
index abc3b0460186..569e69489aa4 100644
--- a/metadata/md5-cache/sci-biology/recon-1.08
+++ b/metadata/md5-cache/sci-biology/recon-1.08
@@ -2,11 +2,12 @@ DEFINED_PHASES=compile install prepare
 DESCRIPTION=Automated de novo identification of repeat families from genomic sequences
 EAPI=6
 HOMEPAGE=http://www.repeatmasker.org/RepeatModeler.html
+INHERIT=toolchain-funcs
 IUSE=examples
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 RDEPEND=dev-lang/perl
 SLOT=0
 SRC_URI=http://www.repeatmasker.org/RECON-1.08.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=2ddd537d912c7c88b6f0b0d203a51613
diff --git a/metadata/md5-cache/sci-biology/rnaview-20040713-r4 b/metadata/md5-cache/sci-biology/rnaview-20040713-r4
index bea36d173d13..dace43fe9f21 100644
--- a/metadata/md5-cache/sci-biology/rnaview-20040713-r4
+++ b/metadata/md5-cache/sci-biology/rnaview-20040713-r4
@@ -2,9 +2,10 @@ DEFINED_PHASES=install prepare
 DESCRIPTION=Generates 2D displays of RNA/DNA secondary structures with tertiary interactions
 EAPI=6
 HOMEPAGE=http://ndbserver.rutgers.edu/services/download/index.html
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~x86
 LICENSE=public-domain
 SLOT=0
 SRC_URI=mirror://gentoo/rnaview-20040713.tar.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=788c156d45287bef4f6aa876055bde4c
diff --git a/metadata/md5-cache/sci-biology/samtools-0.1.20-r4 b/metadata/md5-cache/sci-biology/samtools-0.1.20-r4
index 726f20a19c1e..b376261c3cd7 100644
--- a/metadata/md5-cache/sci-biology/samtools-0.1.20-r4
+++ b/metadata/md5-cache/sci-biology/samtools-0.1.20-r4
@@ -4,10 +4,11 @@ DEPEND=sys-libs/ncurses:0= dev-lang/perl
 DESCRIPTION=Utilities for analysing and manipulating the SAM/BAM alignment formats
 EAPI=7
 HOMEPAGE=http://samtools.sourceforge.net/
+INHERIT=multilib toolchain-funcs
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=MIT
 RDEPEND=sys-libs/ncurses:0= dev-lang/perl
 SLOT=0.1-legacy
 SRC_URI=https://github.com/samtools/samtools/archive/0.1.20.tar.gz -> samtools-0.1.20.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=89941c8b8d527ccc386063a3f533ef77
diff --git a/metadata/md5-cache/sci-biology/samtools-1.13 b/metadata/md5-cache/sci-biology/samtools-1.13
deleted file mode 100644
index 909a66a67260..000000000000
--- a/metadata/md5-cache/sci-biology/samtools-1.13
+++ /dev/null
@@ -1,13 +0,0 @@
-BDEPEND=virtual/pkgconfig
-DEFINED_PHASES=compile configure install prepare
-DEPEND=dev-lang/perl =sci-libs/htslib-1.13*:= sys-libs/ncurses:=[unicode(+)] sys-libs/zlib
-DESCRIPTION=Utilities for analysing and manipulating the SAM/BAM alignment formats
-EAPI=8
-HOMEPAGE=http://www.htslib.org/
-KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
-LICENSE=MIT
-RDEPEND=dev-lang/perl =sci-libs/htslib-1.13*:= sys-libs/ncurses:=[unicode(+)] sys-libs/zlib
-SLOT=0
-SRC_URI=mirror://sourceforge/samtools/samtools-1.13.tar.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
-_md5_=1319bb15b069d25fce506452f0b3a88f
diff --git a/metadata/md5-cache/sci-biology/samtools-1.15 b/metadata/md5-cache/sci-biology/samtools-1.15
deleted file mode 100644
index 6fff3a2de1a1..000000000000
--- a/metadata/md5-cache/sci-biology/samtools-1.15
+++ /dev/null
@@ -1,13 +0,0 @@
-BDEPEND=virtual/pkgconfig
-DEFINED_PHASES=compile configure install prepare
-DEPEND=dev-lang/perl =sci-libs/htslib-1.15*:= sys-libs/ncurses:=[unicode(+)] sys-libs/zlib
-DESCRIPTION=Utilities for analysing and manipulating the SAM/BAM alignment formats
-EAPI=8
-HOMEPAGE=http://www.htslib.org/
-KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
-LICENSE=MIT
-RDEPEND=dev-lang/perl =sci-libs/htslib-1.15*:= sys-libs/ncurses:=[unicode(+)] sys-libs/zlib
-SLOT=0
-SRC_URI=mirror://sourceforge/samtools/samtools-1.15.tar.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
-_md5_=8e65ef700f1f60118807cb5e9e36a185
diff --git a/metadata/md5-cache/sci-biology/samtools-1.15.1 b/metadata/md5-cache/sci-biology/samtools-1.15.1
new file mode 100644
index 000000000000..099c20673cd7
--- /dev/null
+++ b/metadata/md5-cache/sci-biology/samtools-1.15.1
@@ -0,0 +1,14 @@
+BDEPEND=virtual/pkgconfig
+DEFINED_PHASES=compile configure install prepare
+DEPEND=dev-lang/perl =sci-libs/htslib-1.15.1*:= sys-libs/ncurses:=[unicode(+)] sys-libs/zlib
+DESCRIPTION=Utilities for analysing and manipulating the SAM/BAM alignment formats
+EAPI=8
+HOMEPAGE=http://www.htslib.org/
+INHERIT=toolchain-funcs
+KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
+LICENSE=MIT
+RDEPEND=dev-lang/perl =sci-libs/htslib-1.15.1*:= sys-libs/ncurses:=[unicode(+)] sys-libs/zlib
+SLOT=0
+SRC_URI=https://github.com/samtools/samtools/releases/download/1.15.1/samtools-1.15.1.tar.bz2
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
+_md5_=c347f2e80f020ce72d8f21220d346f1f
diff --git a/metadata/md5-cache/sci-biology/seaview-4.6-r1 b/metadata/md5-cache/sci-biology/seaview-4.6-r1
index 7269d7a50790..3da7bfbc37d7 100644
--- a/metadata/md5-cache/sci-biology/seaview-4.6-r1
+++ b/metadata/md5-cache/sci-biology/seaview-4.6-r1
@@ -4,11 +4,12 @@ DEPEND=sci-biology/clustalw:2 sci-biology/phyml || ( sci-libs/libmuscle sci-biol
 DESCRIPTION=A graphical multiple sequence alignment editor
 EAPI=7
 HOMEPAGE=http://pbil.univ-lyon1.fr/software/seaview.html
+INHERIT=desktop toolchain-funcs
 IUSE=+xft
 KEYWORDS=~amd64 ~x86
 LICENSE=public-domain
 RDEPEND=sci-biology/clustalw:2 sci-biology/phyml || ( sci-libs/libmuscle sci-biology/muscle ) sys-libs/zlib x11-libs/fltk:1[xft?] x11-libs/libX11 xft? ( x11-libs/libXft )
 SLOT=0
 SRC_URI=ftp://pbil.univ-lyon1.fr/pub/mol_phylogeny/seaview/archive/seaview_4.6.tar.gz
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=desktop	22952d8f27cac191d75529d4c38e6bfa	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=a742711d8523a4e49524662c12d647c2
diff --git a/metadata/md5-cache/sci-biology/seqan-2.4.0-r1 b/metadata/md5-cache/sci-biology/seqan-2.4.0-r1
index 3f75013a34af..53d384d0619a 100644
--- a/metadata/md5-cache/sci-biology/seqan-2.4.0-r1
+++ b/metadata/md5-cache/sci-biology/seqan-2.4.0-r1
@@ -1,5 +1,5 @@
-BDEPEND=dev-util/ninja >=dev-util/cmake-3.20.5
-DEFINED_PHASES=compile configure install prepare setup test
+BDEPEND=>=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
+DEFINED_PHASES=compile configure install prepare pretend setup test
 DEPEND=app-arch/bzip2:= sys-libs/zlib !!sci-biology/seqan:2.0 !!sci-biology/seqan:2.1 !!sci-biology/seqan:2.2
 DESCRIPTION=C++ Sequence Analysis Library
 EAPI=7
@@ -12,5 +12,5 @@ RDEPEND=app-arch/bzip2:= sys-libs/zlib !!sci-biology/seqan:2.0 !!sci-biology/seq
 REQUIRED_USE=cpu_flags_x86_sse4_1
 SLOT=0
 SRC_URI=https://github.com/seqan/seqan/archive/seqan-v2.4.0.tar.gz
-_eclasses_=cmake	90e2b29417d53718328f3a95227137a0	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
-_md5_=8796fa7c1594d16d8a9b96920de5cf2b
+_eclasses_=cmake	44afbf15c35884f7c840470f1cf05d0d	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multibuild	d26d81f242cb193d899a72bca423d0bd	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
+_md5_=af3f619bf918af3c15697066b1de20bb
diff --git a/metadata/md5-cache/sci-biology/seqan-3.1.0 b/metadata/md5-cache/sci-biology/seqan-3.1.0
index ebec83050450..f3ec26ea8fbe 100644
--- a/metadata/md5-cache/sci-biology/seqan-3.1.0
+++ b/metadata/md5-cache/sci-biology/seqan-3.1.0
@@ -1,4 +1,4 @@
-BDEPEND=dev-util/ninja >=dev-util/cmake-3.20.5
+BDEPEND=>=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install prepare test
 DEPEND=app-arch/bzip2:= dev-cpp/range-v3 dev-libs/cereal sci-libs/lemon sys-libs/zlib:=
 DESCRIPTION=C++ Sequence Analysis Library
@@ -6,11 +6,11 @@ EAPI=8
 HOMEPAGE=https://www.seqan.de/
 INHERIT=cmake
 IUSE=cpu_flags_x86_sse4_2
-KEYWORDS=~amd64 ~amd64-linux
+KEYWORDS=~amd64 ~x86 ~amd64-linux
 LICENSE=BSD GPL-3
 RDEPEND=app-arch/bzip2:= dev-cpp/range-v3 dev-libs/cereal sci-libs/lemon sys-libs/zlib:=
 REQUIRED_USE=cpu_flags_x86_sse4_2
 SLOT=0
 SRC_URI=https://github.com/seqan/seqan3/releases/download/3.1.0/seqan3-3.1.0-Source.tar.xz
-_eclasses_=cmake	90e2b29417d53718328f3a95227137a0	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
-_md5_=79bf85e28c26de53181c27b102f90252
+_eclasses_=cmake	44afbf15c35884f7c840470f1cf05d0d	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
+_md5_=327a33751512d78b13d5acd641ba3385
diff --git a/metadata/md5-cache/sci-biology/sibsim4-0.20 b/metadata/md5-cache/sci-biology/sibsim4-0.20
index b469a92ad135..1f9f2f682070 100644
--- a/metadata/md5-cache/sci-biology/sibsim4-0.20
+++ b/metadata/md5-cache/sci-biology/sibsim4-0.20
@@ -2,9 +2,10 @@ DEFINED_PHASES=configure install
 DESCRIPTION=A rewrite and improvement upon sim4, a DNA-mRNA aligner
 EAPI=7
 HOMEPAGE=http://sibsim4.sourceforge.net/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=mirror://sourceforge/sibsim4/SIBsim4-0.20.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=da65f25e1cebcf8c22efbffb6b2b5c95
diff --git a/metadata/md5-cache/sci-biology/sim4-20030921-r2 b/metadata/md5-cache/sci-biology/sim4-20030921-r2
index efe443aca627..10919f85781a 100644
--- a/metadata/md5-cache/sci-biology/sim4-20030921-r2
+++ b/metadata/md5-cache/sci-biology/sim4-20030921-r2
@@ -2,9 +2,10 @@ DEFINED_PHASES=configure install
 DESCRIPTION=A program to align cDNA and genomic DNA
 EAPI=7
 HOMEPAGE=http://globin.cse.psu.edu/html/docs/sim4.html
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~ppc ~x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=mirror://gentoo/sim4-20030921.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=d9ac88a2e3ccc00187d880fcca7f5db2
diff --git a/metadata/md5-cache/sci-biology/stride-20011129-r1 b/metadata/md5-cache/sci-biology/stride-20011129-r1
index a493152a56b2..9d1d9a118b28 100644
--- a/metadata/md5-cache/sci-biology/stride-20011129-r1
+++ b/metadata/md5-cache/sci-biology/stride-20011129-r1
@@ -2,10 +2,11 @@ DEFINED_PHASES=configure install
 DESCRIPTION=Protein secondary structure assignment from atomic coordinates
 EAPI=7
 HOMEPAGE=http://webclu.bio.wzw.tum.de/stride/
+INHERIT=toolchain-funcs
 KEYWORDS=amd64 ~ppc x86 ~amd64-linux ~x86-linux
 LICENSE=STRIDE
 RESTRICT=mirror bindist
 SLOT=0
 SRC_URI=ftp://ftp.ebi.ac.uk/pub/software/unix/stride/src/stride.tar.gz -> stride-20011129.tar.gz https://dev.gentoo.org/~pacho/stride/stride-20060723-update.patch.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=9ec341e7ee97fc8fd15fa6e200e17bfd
diff --git a/metadata/md5-cache/sci-biology/t-coffee-11.00-r2 b/metadata/md5-cache/sci-biology/t-coffee-11.00-r2
index 45378df1b920..89baa6b4617c 100644
--- a/metadata/md5-cache/sci-biology/t-coffee-11.00-r2
+++ b/metadata/md5-cache/sci-biology/t-coffee-11.00-r2
@@ -2,10 +2,11 @@ DEFINED_PHASES=compile install prepare
 DESCRIPTION=A multiple sequence alignment package
 EAPI=6
 HOMEPAGE=http://www.tcoffee.org/Projects_home_page/t_coffee_home_page.html
+INHERIT=toolchain-funcs
 KEYWORDS=~amd64 ~ppc ~ppc64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-2
 RDEPEND=sci-biology/clustalw sci-chemistry/tm-align
 SLOT=0
 SRC_URI=http://www.tcoffee.org/Packages/Beta/Latest/T-COFFEE_distribution_Version_11.00.4466924.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=5c54b109c5b8bef93adbc5f99ddd7114
diff --git a/metadata/md5-cache/sci-biology/treeviewx-0.5.1-r3 b/metadata/md5-cache/sci-biology/treeviewx-0.5.1-r3
index 326322db07fa..f226841c1a25 100644
--- a/metadata/md5-cache/sci-biology/treeviewx-0.5.1-r3
+++ b/metadata/md5-cache/sci-biology/treeviewx-0.5.1-r3
@@ -4,10 +4,11 @@ DEPEND=x11-libs/wxGTK:3.0[X]
 DESCRIPTION=A phylogenetic tree viewer
 EAPI=7
 HOMEPAGE=http://darwin.zoology.gla.ac.uk/~rpage/treeviewx/
+INHERIT=autotools wxwidgets
 KEYWORDS=amd64 x86
 LICENSE=GPL-2
 RDEPEND=x11-libs/wxGTK:3.0[X]
 SLOT=0
 SRC_URI=http://darwin.zoology.gla.ac.uk/~rpage/treeviewx/download/0.5/tv-0.5.1.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c	wxwidgets	c09e9b94378cadaf6ef86ec1534c0fd6
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c	wxwidgets	c09e9b94378cadaf6ef86ec1534c0fd6
 _md5_=14493f936bb599dd7faec748cece70f3
diff --git a/metadata/md5-cache/sci-biology/trnascan-se-1.31 b/metadata/md5-cache/sci-biology/trnascan-se-1.31
index 93aa0bba4028..b0f8d68f6b93 100644
--- a/metadata/md5-cache/sci-biology/trnascan-se-1.31
+++ b/metadata/md5-cache/sci-biology/trnascan-se-1.31
@@ -2,9 +2,10 @@ DEFINED_PHASES=install prepare test
 DESCRIPTION=tRNA detection in large-scale genome sequences
 EAPI=6
 HOMEPAGE=http://lowelab.ucsc.edu/tRNAscan-SE/
+INHERIT=perl-functions toolchain-funcs
 KEYWORDS=amd64 x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=http://lowelab.ucsc.edu/software/tRNAscan-SE.tar.gz -> trnascan-se-1.31.tar.gz
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	perl-functions	fea344a91ebf37efadf172c6a3de5a72	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	perl-functions	fea344a91ebf37efadf172c6a3de5a72	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=3f4bcdf31fe276f90a95e2f4b311deae
diff --git a/metadata/md5-cache/sci-biology/uchime-4.2.40 b/metadata/md5-cache/sci-biology/uchime-4.2.40
index 30f1db729ec4..6be69463de41 100644
--- a/metadata/md5-cache/sci-biology/uchime-4.2.40
+++ b/metadata/md5-cache/sci-biology/uchime-4.2.40
@@ -1,4 +1,4 @@
-BDEPEND=dev-util/ninja >=dev-util/cmake-3.20.5
+BDEPEND=>=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install prepare test
 DESCRIPTION=Fast, accurate chimera detection
 EAPI=7
@@ -8,5 +8,5 @@ KEYWORDS=amd64 x86 ~amd64-linux ~x86-linux
 LICENSE=public-domain
 SLOT=0
 SRC_URI=https://www.drive5.com/uchime/uchime4.2.40_src.tar.gz
-_eclasses_=cmake	90e2b29417d53718328f3a95227137a0	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
+_eclasses_=cmake	44afbf15c35884f7c840470f1cf05d0d	edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	58ec4e54962bf45d065fb95030701514	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c	xdg-utils	fffb53a53cf17c9c0c998a3c0a590c7e
 _md5_=421c75fd545cd9d38575321e00aeab36
diff --git a/metadata/md5-cache/sci-biology/ucsc-genome-browser-260-r1 b/metadata/md5-cache/sci-biology/ucsc-genome-browser-260-r1
index 68bbd74a9ba9..5ea4d1250a30 100644
--- a/metadata/md5-cache/sci-biology/ucsc-genome-browser-260-r1
+++ b/metadata/md5-cache/sci-biology/ucsc-genome-browser-260-r1
@@ -11,5 +11,5 @@ RDEPEND=dev-libs/openssl:0= media-libs/libpng:0= !<sci-biology/ucsc-genome-brows
 REQUIRED_USE=server? ( mysql )
 SLOT=0
 SRC_URI=http://hgdownload.cse.ucsc.edu/admin/jksrc.v260.zip
-_eclasses_=desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	webapp	d872f28d7595b70dd46545199ef35fb0	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	webapp	d872f28d7595b70dd46545199ef35fb0	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=35cb93e40ad2d78c190e860dd3944557
diff --git a/metadata/md5-cache/sci-biology/unafold-3.8-r1 b/metadata/md5-cache/sci-biology/unafold-3.8-r1
index d349ddd0a54a..0232bb682abc 100644
--- a/metadata/md5-cache/sci-biology/unafold-3.8-r1
+++ b/metadata/md5-cache/sci-biology/unafold-3.8-r1
@@ -3,11 +3,12 @@ DEPEND=media-libs/freeglut media-libs/gd virtual/opengl
 DESCRIPTION=Unified Nucleic Acid Folding and hybridization package
 EAPI=7
 HOMEPAGE=http://mfold.rna.albany.edu/
+INHERIT=flag-o-matic
 IUSE=custom-cflags
 KEYWORDS=~amd64 ~x86
 LICENSE=unafold
 RDEPEND=media-libs/freeglut media-libs/gd virtual/opengl
 SLOT=0
 SRC_URI=http://dinamelt.bioinfo.rpi.edu/download/unafold-3.8.tar.bz2
-_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=edos2unix	33e347e171066657f91f8b0c72ec8773	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=140380fdaf468f37ce9bb27d0026ec8e
diff --git a/metadata/md5-cache/sci-biology/vcftools-0.1.14 b/metadata/md5-cache/sci-biology/vcftools-0.1.14
index d3eb09a79260..6378220f4ac9 100644
--- a/metadata/md5-cache/sci-biology/vcftools-0.1.14
+++ b/metadata/md5-cache/sci-biology/vcftools-0.1.14
@@ -10,5 +10,5 @@ LICENSE=LGPL-3
 RDEPEND=sys-libs/zlib dev-lang/perl:= lapack? ( virtual/lapack )
 SLOT=0
 SRC_URI=https://github.com/vcftools/vcftools/releases/download/v0.1.14/vcftools-0.1.14.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	perl-functions	fea344a91ebf37efadf172c6a3de5a72	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	perl-functions	fea344a91ebf37efadf172c6a3de5a72	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=82adffd84f2a93745e683b498b79fbe8
diff --git a/metadata/md5-cache/sci-biology/vcftools-0.1.16 b/metadata/md5-cache/sci-biology/vcftools-0.1.16
index de36683b071a..84542d84c101 100644
--- a/metadata/md5-cache/sci-biology/vcftools-0.1.16
+++ b/metadata/md5-cache/sci-biology/vcftools-0.1.16
@@ -4,11 +4,12 @@ DEPEND=sys-libs/zlib dev-lang/perl:= lapack? ( virtual/lapack )
 DESCRIPTION=Tools for working with VCF (Variant Call Format) files
 EAPI=8
 HOMEPAGE=http://vcftools.sourceforge.net/
+INHERIT=autotools flag-o-matic perl-functions toolchain-funcs
 IUSE=lapack
 KEYWORDS=~amd64 ~x86
 LICENSE=LGPL-3
 RDEPEND=sys-libs/zlib dev-lang/perl:= lapack? ( virtual/lapack )
 SLOT=0
 SRC_URI=https://github.com/vcftools/vcftools/releases/download/v0.1.16/vcftools-0.1.16.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	flag-o-matic	a500d7cc40da3de38c361e889153bdf7	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	perl-functions	fea344a91ebf37efadf172c6a3de5a72	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	multilib	4fbbbc98f236f1b43acd99476bc3cd85	perl-functions	fea344a91ebf37efadf172c6a3de5a72	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=faeb202e0aded0cb660ea87d6d7be81b
diff --git a/metadata/md5-cache/sci-biology/velvet-1.2.10 b/metadata/md5-cache/sci-biology/velvet-1.2.10
index f316c3bd4145..3948eb800c7c 100644
--- a/metadata/md5-cache/sci-biology/velvet-1.2.10
+++ b/metadata/md5-cache/sci-biology/velvet-1.2.10
@@ -3,10 +3,11 @@ DEFINED_PHASES=compile install prepare test
 DESCRIPTION=A sequence assembler for very short reads
 EAPI=8
 HOMEPAGE=https://www.ebi.ac.uk/~zerbino/velvet/
+INHERIT=flag-o-matic toolchain-funcs
 IUSE=doc openmp
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
 SLOT=0
 SRC_URI=https://www.ebi.ac.uk/~zerbino/velvet/velvet_1.2.10.tgz
-_eclasses_=flag-o-matic	a500d7cc40da3de38c361e889153bdf7	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=flag-o-matic	a3abd6002fafb3022597be6b8d01f88b	multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=f48eb0348a1ac91d41dde22d3ced2ea1
diff --git a/metadata/md5-cache/sci-biology/wise-2.4.0_alpha-r1 b/metadata/md5-cache/sci-biology/wise-2.4.0_alpha-r1
index 5298f6a800ea..1adb93b5dc73 100644
--- a/metadata/md5-cache/sci-biology/wise-2.4.0_alpha-r1
+++ b/metadata/md5-cache/sci-biology/wise-2.4.0_alpha-r1
@@ -4,11 +4,12 @@ DEPEND=~sci-biology/hmmer-2.3.2
 DESCRIPTION=Intelligent algorithms for DNA searches
 EAPI=8
 HOMEPAGE=http://www.ebi.ac.uk/Wise2/
+INHERIT=toolchain-funcs
 IUSE=doc
 KEYWORDS=~amd64 ~x86
 LICENSE=BSD
 RDEPEND=~sci-biology/hmmer-2.3.2
 SLOT=0
 SRC_URI=ftp://ftp.ebi.ac.uk/pub/software/wise2/wise2.4.0alpha.tar.gz https://dev.gentoo.org/~mgorny/dist/wise-2.4.0_alpha-patchset.tar.bz2
-_eclasses_=multilib	4a33c9008e5ee30cb8840a3fdc24df2b	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8
+_eclasses_=multilib	4fbbbc98f236f1b43acd99476bc3cd85	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb
 _md5_=34f9a1f8b8f239e402200b9b5cb4f3cc
diff --git a/metadata/md5-cache/sci-biology/yass-1.14-r2 b/metadata/md5-cache/sci-biology/yass-1.14-r2
index fb0a4b230fc0..0728a88ebf47 100644
--- a/metadata/md5-cache/sci-biology/yass-1.14-r2
+++ b/metadata/md5-cache/sci-biology/yass-1.14-r2
@@ -10,5 +10,5 @@ LICENSE=GPL-2
 RDEPEND=dmalloc? ( dev-libs/dmalloc )
 SLOT=0
 SRC_URI=http://bioinfo.lifl.fr/yass/files/yass-1.14.tar.gz
-_eclasses_=autotools	b46e8992a8126c894fbdc8084fc040c4	desktop	c0d27bf73aa08ca05b663dbd31fbef28	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	9f813bb3c47cf2e60619a663b87c5f4e	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4a33c9008e5ee30cb8840a3fdc24df2b	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	badd6e329e1f3e6bee99b35bf8763ce8	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
+_eclasses_=autotools	136117fb43a9bf5598530e9cc642f710	desktop	22952d8f27cac191d75529d4c38e6bfa	edos2unix	33e347e171066657f91f8b0c72ec8773	epatch	28f0f3c0226306ec5f49e13bf851f171	estack	055c42df72f76a4f45ec92b35e83cd56	eutils	dab5d8ec471d025b79c9e6906bcf3bff	gnuconfig	b6b3e92f8b8c996400074b5f61a59256	libtool	241a8f577b9781a42a7421e53448a44e	ltprune	97143780d341cc8d8f1d4c6187a36d29	multilib	4fbbbc98f236f1b43acd99476bc3cd85	preserve-libs	a8e50acee31b5759b4df1f7707cae54b	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	toolchain-funcs	e9da88162e7a3c60376e80c2c2adcdfb	vcs-clean	d271b7bc7e6a009758d7d4ef749174e3	wrapper	4a1902f969e5718126434fc35f3a0d9c
 _md5_=3a4ba9b4e7b8efec51cfc79d261fefd3
author	V3n3RiX <venerix@koprulu.sector>	2022-06-29 12:04:12 +0100
committer	V3n3RiX <venerix@koprulu.sector>	2022-06-29 12:04:12 +0100
commit	0f558761aa2dee1017b4751e4017205e015a9560 (patch)
tree	037df795519468a25d9362b4e95cdaeb84eb1cf9 /metadata/md5-cache/sci-biology
parent	752d6256e5204b958b0ef7905675a940b5e9172f (diff)